Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
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Carotegrast methyl
CAS:401905-67-7
Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is …
Formula:
C28H26Cl2N4O5
Purity:
99.40%
Color and Shape:
Solid
Molecular weight:
569.44
Ref: TM-T30751
| 1mg | 85.00 € | ||
| 5mg | 180.00 € | ||
| 10mg | 297.00 € | ||
| 25mg | 590.00 € | ||
| 50mg | 906.00 € | ||
| 100mg | 1,319.00 € | ||
| 1mL*10mM (DMSO) | 215.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Irigenin
CAS:548-76-5
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin …
Formula:
C18H16O8
Purity:
99.71% - 99.85%
Color and Shape:
Solid
Molecular weight:
360.31
Ref: TM-T3862
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 180.00 € | ||
| 100mg | 271.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
A-286982
CAS:280749-17-9
A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.
Formula:
C24H27N3O4S
Purity:
97.81%
Color and Shape:
Solid
Molecular weight:
453.55
Ref: TM-T21781
| 1mg | 35.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 515.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Leukadherin-1
CAS:344897-95-6
Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.
Formula:
C22H15NO4S2
Purity:
98% - 98.49%
Color and Shape:
Solid
Molecular weight:
421.49
Ref: TM-T3638
| 5mg | 46.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 116.00 € | ||
| 50mg | 200.00 € | ||
| 100mg | 324.00 € | ||
| 200mg | 485.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Cyclo(RGDyK) trifluoroacetate
CAS:250612-42-1
Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
Formula:
C31H43F6N9O12
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
847.72
Ref: TM-T6813
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 454.00 € | ||
| 100mg | 661.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Cyclo(-RGDfK) TFA
CAS:500577-51-5
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
Formula:
C29H42F3N9O9
Purity:
99.54%
Color and Shape:
Solid
Molecular weight:
717.69
Ref: TM-T6812L
| 1mg | 51.00 € | ||
| 5mg | 98.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 384.00 € | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
GLPG0187
CAS:1320346-97-1
GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).
Formula:
C29H37N7O5S
Purity:
100% - 99.12%
Color and Shape:
Solid
Molecular weight:
595.71
Ref: TM-T4259
| 1mg | 46.00 € | ||
| 5mg | 101.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 538.00 € | ||
| 500mg | 1,170.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Natalizumab
CAS:189261-10-7
Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.
Purity:
98.00%
Color and Shape:
Liquid
Molecular weight:
N/A
Ref: TM-T12177
| 1mg | 163.00 € | ||
| 2mg | 233.00 € | ||
| 5mg | 396.00 € | ||
| 10mg | 637.00 € | ||
| 25mg | 926.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
LXW7
CAS:1313004-77-1
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent …
Formula:
C29H48N12O12S2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
820.89
Ref: TM-TP1474
| 1mg | 85.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
ILK-IN-2
CAS:1333146-24-9
ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of …
Formula:
C30H30F3N5O
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
533.59
Ref: TM-T5488
| 1mg | 47.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 274.00 € | ||
| 200mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 133.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
CWHM-12
CAS:1564286-55-0
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).
Formula:
C26H32BrN5O6
Purity:
98.05% - 98.5%
Color and Shape:
Solid
Molecular weight:
590.47
Ref: TM-TQ0250
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 538.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
BIO-1211
CAS:187735-94-0
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 …
Formula:
C36H48N6O9
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
708.8
Ref: TM-T21868
| 1mg | 110.00 € | ||
| 2mg | 163.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 435.00 € | ||
| 25mg | 702.00 € | ||
| 50mg | 926.00 € | ||
| 100mg | 1,295.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Cyclo(-RGDfK)
CAS:161552-03-0
Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of …
Formula:
C27H41N9O7
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
603.67
Ref: TM-T6812
| 1mg | 46.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 272.00 € | ||
| 50mg | 378.00 € | ||
| 100mg | 530.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
PND-1186
CAS:1061353-68-1
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
Formula:
C25H26F3N5O3
Purity:
99.14% - ≥98%
Color and Shape:
Solid
Molecular weight:
501.5
Ref: TM-T1950
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 199.00 € | ||
| 100mg | 289.00 € | ||
| 500mg | 696.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
OSU-T315
CAS:2070015-22-2
OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.
Formula:
C30H30F3N5O
Purity:
98.03%
Color and Shape:
Solid
Molecular weight:
533.59
Ref: TM-T5485
| 1mg | 96.00 € | ||
| 2mg | 143.00 € | ||
| 5mg | 232.00 € | ||
| 10mg | 373.00 € | ||
| 25mg | 640.00 € | ||
| 50mg | 909.00 € | ||
| 100mg | 1,210.00 € | ||
| 500mg | 2,452.00 € | ||
| 1mL*10mM (DMSO) | 303.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Lifitegrast
CAS:1025967-78-5
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
Formula:
C29H24Cl2N2O7S
Purity:
99.39% - 99.66%
Color and Shape:
Solid
Molecular weight:
615.48
Ref: TM-T3977
| 5mg | 39.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 142.00 € | ||
| 100mg | 222.00 € | ||
| 500mg | 546.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
ILK-IN-3
CAS:6975-75-3
ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.
Formula:
C10H12N6O
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
232.24
Ref: TM-T8523
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 322.00 € | ||
| 100mg | 513.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
SB273005
CAS:205678-31-5
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for …
Formula:
C22H24F3N3O4
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
451.44
Ref: TM-T6657
| 1mg | 147.00 € | ||
| 2mg | 208.00 € | ||
| 5mg | 350.00 € | ||
| 10mg | 519.00 € | ||
| 25mg | 847.00 € | ||
| 50mg | 1,443.00 € | ||
| 1mL*10mM (DMSO) | 376.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Tirofiban
CAS:144494-65-5
Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 …
Formula:
C22H36N2O5S
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
440.6
Ref: TM-T6182
| 5mg | 53.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 190.00 € | ||
| 100mg | 313.00 € | ||
| 500mg | 740.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Firategrast
CAS:402567-16-2
Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport …
Formula:
C27H27F2NO6
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
499.5
Ref: TM-TQ0291
| 1mg | 46.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 139.00 € | ||
| 25mg | 279.00 € | ||
| 50mg | 458.00 € | ||
| 100mg | 738.00 € | ||
| 200mg | 1,004.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
