Ferroptosis
Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.
Found 227 products of "Ferroptosis"
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ZX703
ZX703 is a protein hydrolysis-targeting chimera (PROTAC) that mediates the degradation of GPX4 through the ubiquitin-proteasome and autophagy-lysosome pathways, with a DC50 of 0.315 µM. It induces the accumulation of lipid reactive oxygen species (ROS), thereby promoting ferroptosis in cancer cells.Formula:C54H67ClN8O9SMolecular weight:1039.69Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:Iron(III) compound induces ferroptosis in NB1 cells at 3μM, not apoptosis/necroptosis; inhibits various cancers, effective against drug-resistant NALM-6.Formula:C20H14ClFeN2O2Color and Shape:SolidMolecular weight:405.64CQ-ER
CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).Formula:C33H33N7O6SColor and Shape:SolidMolecular weight:655.72W1131 TFA
W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.Formula:C25H20F3N5O6Purity:98.1%Color and Shape:SolidMolecular weight:543.45Ref: TM-T80847
1mg92.00€5mg188.00€10mg311.00€25mg628.00€50mg1,008.00€100mg1,596.00€1mL*10mM (DMSO)To inquire84-B10
CAS:84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.Formula:C25H22F3NO5Purity:99.76%Color and Shape:SolidMolecular weight:473.44Ref: TM-T75268
1mg47.00€5mg92.00€10mg152.00€25mg289.00€50mg447.00€100mg670.00€200mg888.00€1mL*10mM (DMSO)92.00€Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Purity:98%Color and Shape:Odour SolidGPX4-IN-7
GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.Formula:C25H23ClN4O4Purity:98%Color and Shape:SolidMolecular weight:478.93Ferroptosis-IN-1
Ferroptosis-IN-1, a diterpene derived from A.Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.5Idebenone
CAS:Formula:C19H30O5Purity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:338.44Cerivastatin sodium
CAS:Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.Formula:C26H33FNNaO5Purity:98.50% - 99.67%Color and Shape:SolidMolecular weight:481.53CuATSP
CAS:CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.Formula:C18H18CuN6S2Purity:97.09%Color and Shape:SolidMolecular weight:446.05CuATSM
CAS:Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.Formula:C8H14CuN6S2Color and Shape:SolidMolecular weight:321.92CCW16
CAS:CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.Formula:C22H20ClNO3Purity:97%Color and Shape:SolidMolecular weight:381.85BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formula:C26H26F3N7O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:525.53Ref: TM-T2488
1mg34.00€2mg40.00€5mg59.00€10mg96.00€25mg200.00€50mg334.00€100mg557.00€1mL*10mM (DMSO)70.00€UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Formula:C25H38ClN5O2SPurity:99.62%Color and Shape:SolidMolecular weight:508.12Ref: TM-T8662
1mgTo inquire2mg49.00€5mg80.00€10mg111.00€25mg160.00€50mg202.00€100mg283.00€200mg419.00€1mL*10mM (DMSO)89.00€Baicalein monohydrate
CAS:Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.Formula:C15H12O6Color and Shape:SolidMolecular weight:288.25TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purity:99.17% - 99.53%Color and Shape:White Solid PowderMolecular weight:166.22Ferrostatin-1
CAS:Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!Formula:C15H22N2O2Purity:96.1% - 99.68%Color and Shape:SolidMolecular weight:262.35Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormula:C21H26N7Na4O17P3Purity:97.15% - >99.99%Color and Shape:SolidMolecular weight:833.35
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