CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Found 546 products of "CDK"
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CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurity:98.81%Color and Shape:SolidMolecular weight:355.82Ref: TM-T14943
1mg34.00€2mg46.00€5mg71.00€10mg92.00€25mg177.00€50mg314.00€100mg518.00€1mL*10mM (DMSO)78.00€CDK9-IN-15
CAS:CDK9-IN-15: potent CDK9 inhibitor, blocks P-TEFb phosphorylation, inhibits transcription, reduces mRNA, induces tumor cell apoptosis.Formula:C16H11N3OSPurity:99.32%Color and Shape:SolidMolecular weight:293.34Ref: TM-T60619
5mg46.00€10mg71.00€25mg126.00€50mg180.00€100mg260.00€200mg364.00€1mL*10mM (DMSO)44.00€Atuveciclib S-Enantiomer
CAS:Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.Formula:C18H18FN5O2SPurity:98%Color and Shape:SolidMolecular weight:387.43CDK2-IN-13
CAS:CDK2-IN-13: Potent CDK2 inhibitor, arrests cell cycle, induces apoptosis, IC50=12 µM, used in cancer research.Formula:C13H12ClN5Color and Shape:SoildMolecular weight:273.72NSC 625987
CAS:NSC 625987, Selective CDK4 inhibitor (IC50=0.2 μM), >500-fold selectivity over CDK2, used for p16-associated tumor studies.Formula:C15H13NO2SPurity:98%Color and Shape:SolidMolecular weight:271.33Ref: TM-T23092
1mg63.00€2mg105.00€5mg137.00€10mgTo inquire25mgTo inquire50mg595.00€100mg893.00€1mL*10mM (DMSO)To inquireARN22089
CAS:ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.Formula:C23H27N5Purity:98.37%Color and Shape:SolidMolecular weight:373.49Ref: TM-T85727
1mg109.00€5mg260.00€10mg385.00€25mg647.00€50mg964.00€100mg1,431.00€200mg1,963.00€1mL*10mM (DMSO)286.00€Cdc7-IN-4
CAS:Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.Formula:C22H24F3N5O4Purity:98%Color and Shape:SolidMolecular weight:479.45BAY-958
CAS:BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.Formula:C17H16FN5O3SPurity:98%Color and Shape:SolidMolecular weight:389.4TP1287
CAS:TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib.Formula:C21H21ClNO8PColor and Shape:SolidMolecular weight:481.82Aloisine A
CAS:Aloisine A, a CDK/GSK-3 inhibitor with IC50: Cdk1/B-150nM, Cdk2/A-120nM, Cdk2/E-400nM, Cdk5/25-200nM, Cdk5/35-160nM, GSK-3α-500nM, GSK-3β-650nM, JNK-3-10μM.Formula:C16H17N3OPurity:98%Color and Shape:SolidMolecular weight:267.33CLK1-IN-2
CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.Formula:C16H12Cl2N2O2SColor and Shape:SolidMolecular weight:367.25CDK4/6-IN-8
CAS:CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).Formula:C18H18N6O5Color and Shape:SolidMolecular weight:398.37NSC 693868
CAS:CDKs and GSK-3 inhibitorFormula:C9H7N5Purity:98%Color and Shape:SolidMolecular weight:185.19(E/Z)-BIO-acetoxime
CAS:(E/Z)-BIO-acetoxime: potent GSK-3 α/β inhibitor; IC50: GSK-3α/β 10nM, CDK5/p25 2.4μM, CDK2/A 4.3μM, CDK1/B 63μM.Formula:C18H12BrN3O3Color and Shape:SolidMolecular weight:398.21MFH290
CAS:MFH290 is a selective CDK12/13 inhibitor, covalently bonding with CDK12 Cys-1039, blocks Pol II CTD phosphorylation, and enhances olaparib's efficacy.Formula:C26H31N5O3S2Color and Shape:SolidMolecular weight:525.69RP-106
CAS:RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3.Formula:C17H19N3OPurity:98%Color and Shape:SolidMolecular weight:281.35CDK8-IN-10
CAS:CDK8-IN-10 is a selective and potent inhibitor of cell cycle protein-dependent kinase (CDK8) (IC50: 8.25 nM) that can be used to study cancer.Formula:C25H15ClF3N5O3Color and Shape:SolidMolecular weight:525.87CDK4/6-IN-12
CAS:CDK4/6-IN-12 inhibits CDK4/6 with IC50s of 592.3 nM & 3090 nM, useful in cancer research.Formula:C12H10N6Color and Shape:SolidMolecular weight:238.25CCT068127
CAS:CCT068127 is a potent CDK2 and CDK9 inhibitor.Formula:C19H27N7OColor and Shape:SolidMolecular weight:369.46(S)-CR8
CAS:(S)-CR8 is an effective second-generation cyclin-dependent kinase inhibitor.Formula:C24H29N7OColor and Shape:SolidMolecular weight:431.53
