CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
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ON123300
CAS:1357470-29-1
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
Formula:
C24H27N7O
Purity:
99.22% - 99.53%
Color and Shape:
Solid
Molecular weight:
429.52
Ref: TM-T6920
| 1mg | 46.00 € | ||
| 2mg | 61.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 146.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 437.00 € | ||
| 100mg | 635.00 € | ||
| 200mg | 515.00 € | ||
| 500mg | 1,291.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ribociclib
CAS:1211441-98-3
Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50:10/39 nM).
Formula:
C23H30N8O
Purity:
100% - 99.96%
Color and Shape:
Solid
Molecular weight:
434.54
Ref: TM-T6199
| 2mg | 42.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 116.00 € | ||
| 100mg | 168.00 € | ||
| 500mg | 412.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Milciclib
CAS:802539-81-7
Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. …
Formula:
C25H32N8O
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
460.57
Ref: TM-T6081
| 1mg | 91.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 307.00 € | ||
| 25mg | 519.00 € | ||
| 50mg | 748.00 € | ||
| 100mg | 1,025.00 € | ||
| 200mg | 807.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
YKL-5-124
CAS:1957203-01-8
YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 …
Formula:
C28H33N7O3
Purity:
99.5%
Color and Shape:
Solid
Molecular weight:
515.61
Ref: TM-T22461
| 1mg | 94.00 € | ||
| 2mg | 132.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 334.00 € | ||
| 25mg | 536.00 € | ||
| 50mg | 764.00 € | ||
| 100mg | 1,019.00 € | ||
| 1mL*10mM (DMSO) | 224.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BGG463
CAS:890129-26-7
BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 …
Formula:
C30H29F3N6O3
Purity:
100% - 95.05%
Color and Shape:
Solid
Molecular weight:
578.58
Ref: TM-T4618
| 1mg | 61.00 € | ||
| 2mg | 85.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 345.00 € | ||
| 50mg | 494.00 € | ||
| 100mg | 716.00 € | ||
| 1mL*10mM (DMSO) | 153.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ro-3306
CAS:872573-93-8
RO-3306: ATP-competitive CDK1 inhibitor, Ki 20 nM, >15x more selective than other human kinases.
Formula:
C18H13N3OS2
Purity:
97.67% - 99.74%
Color and Shape:
Solid
Molecular weight:
351.45
Ref: TM-T2356
| 1mg | 38.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 153.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 346.00 € | ||
| 200mg | 510.00 € | ||
| 500mg | 812.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KenPaullone
CAS:142273-20-9
KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell …
Formula:
C16H11BrN2O
Purity:
97.92% - 98.99%
Color and Shape:
Tan Solid
Molecular weight:
327.18
Ref: TM-T2247
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 314.00 € | ||
| 100mg | 465.00 € | ||
| 500mg | 1,056.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NU6027
CAS:220036-08-8
NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 …
Formula:
C11H17N5O2
Purity:
98.36%
Color and Shape:
Solid
Molecular weight:
251.29
Ref: TM-T6612
| 5mg | 43.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 271.00 € | ||
| 200mg | 391.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Abemaciclib
CAS:1231929-97-7
Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.
Formula:
C27H32F2N8
Purity:
99.39% - 99.87%
Color and Shape:
Solid
Molecular weight:
506.59
Ref: TM-T2381
| 5mg | 52.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 121.00 € | ||
| 200mg | 154.00 € | ||
| 500mg | 268.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NSC23005 Sodium
CAS:1796596-46-7
NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem …
Formula:
C13H16NNaO4S
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
305.32
Ref: TM-T3589
| 1mg | 46.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 611.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BSJ-4-116
CAS:2519823-34-6
BSJ-4-116: potent, selective CDK12 PROTAC, IC50 = 6 nM; downregulates DDR genes, induces premature transcription …
Formula:
C40H49ClN8O8S
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
837.38
Ref: TM-T9117
| 1mg | 54.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 591.00 € | ||
| 100mg | 884.00 € | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ALSTERPAULLONE
CAS:237430-03-4
Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec
Formula:
C16H11N3O3
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
293.28
Ref: TM-T7426
| 1mg | 56.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 598.00 € | ||
| 200mg | 805.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BS-181 hydrochloride
CAS:1397219-81-6
BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.
Formula:
C22H32N6·HCl
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
416.99
Ref: TM-T6162
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 643.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
JNJ-7706621
CAS:443797-96-4
JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.
Formula:
C15H12F2N6O3S
Purity:
99.1% - 99.66%
Color and Shape:
Solid
Molecular weight:
394.36
Ref: TM-T6126
| 1mg | 51.00 € | ||
| 2mg | 66.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 277.00 € | ||
| 50mg | 508.00 € | ||
| 100mg | 713.00 € | ||
| 500mg | 1,448.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Toyocamycin
CAS:606-58-6
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits …
Formula:
C12H13N5O4
Purity:
98.1% - 98.17%
Color and Shape:
Solid
Molecular weight:
291.26
Ref: TM-T17143
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 199.00 € | ||
| 100mg | 347.00 € | ||
| 500mg | 810.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SR-4835
CAS:2387704-62-1
SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; …
Formula:
C21H20Cl2N10O
Purity:
100% - 98.87%
Color and Shape:
Solid
Molecular weight:
499.36
Ref: TM-T8325
| 1mg | 55.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 381.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 807.00 € | ||
| 500mg | 1,643.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SU-9516
CAS:666837-93-0
SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.
Formula:
C13H11N3O2
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
241.25
Ref: TM-T8819
| 1mg | 90.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 317.00 € | ||
| 100mg | 413.00 € | ||
| 200mg | 353.00 € | ||
| 500mg | 920.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Purvalanol A
CAS:212844-53-6
Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM …
Formula:
C19H25ClN6O
Purity:
98.13% - 98.91%
Color and Shape:
Powder
Molecular weight:
388.89
Ref: TM-T2059
| 5mg | 39.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 193.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Senexin B
CAS:1449228-40-3
Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of …
Formula:
C27H26N6O
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
450.53
Ref: TM-T8430
| 1mg | 96.00 € | ||
| 2mg | 130.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 304.00 € | ||
| 25mg | 484.00 € | ||
| 50mg | 650.00 € | ||
| 100mg | 899.00 € | ||
| 1mL*10mM (DMSO) | 214.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Fadraciclib
CAS:1070790-89-4
Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).
Formula:
C21H31N7O
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
397.52
Ref: TM-TQ0053
| 1mg | 47.00 € | ||
| 5mg | 98.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 293.00 € | ||
| 50mg | 422.00 € | ||
| 100mg | 593.00 € | ||
| 200mg | 799.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
