CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
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BMS-265246
CAS:582315-72-8
BMS-265246 is a potent and selective CDK1/2 inhibitor.
Formula:
C18H17F2N3O2
Purity:
98.77% - 99.55%
Color and Shape:
Solid
Molecular weight:
345.34
Ref: TM-T2679
| 1mg | 35.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 335.00 € | ||
| 100mg | 480.00 € | ||
| 200mg | 652.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
HQ461
CAS:1226443-41-9
HQ461, a molecular glue, boosts CDK12-DDB1 binding, lowers cyclin K, impedes CDK12 phosphorylation, hinders DNA …
Formula:
C15H15N5OS2
Purity:
98.11%
Color and Shape:
Liquid
Molecular weight:
345.44
Ref: TM-T9849
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 338.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 810.00 € | ||
| 500mg | 1,644.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
AT7519 Hydrochloride
CAS:902135-91-5
AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.
Formula:
C16H18Cl3N5O2
Purity:
99.66% - 99.9%
Color and Shape:
Solid
Molecular weight:
418.71
Ref: TM-T1778
| 5mg | 57.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 166.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
NG 52
CAS:212779-48-1
NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase …
Formula:
C16H19ClN6O
Purity:
98% - 99.36%
Color and Shape:
Solid
Molecular weight:
346.81
Ref: TM-T2028
| 1mg | 74.00 € | ||
| 2mg | 97.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 515.00 € | ||
| 50mg | 743.00 € | ||
| 100mg | 1,035.00 € | ||
| 500mg | 2,080.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
THZ1
CAS:1604810-83-4
THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located …
Formula:
C31H28ClN7O2
Purity:
95.09% - 99.27%
Color and Shape:
Solid
Molecular weight:
566.05
Ref: TM-T3664
| 5mg | 88.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 474.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Bromosporine
CAS:1619994-69-2
Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), …
Formula:
C17H20N6O4S
Purity:
99.4% - 99.65%
Color and Shape:
Solid
Molecular weight:
404.44
Ref: TM-T6255
| 1mg | 52.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 180.00 € | ||
| 25mg | 330.00 € | ||
| 50mg | 560.00 € | ||
| 100mg | 810.00 € | ||
| 500mg | 1,605.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Briciclib
CAS:865783-99-9
Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.
Formula:
C19H23O10PS
Purity:
98% - 99.84%
Color and Shape:
Solid
Molecular weight:
474.42
Ref: TM-T3207
| 1mg | 47.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 560.00 € | ||
| 500mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
RGB-286638 free base
CAS:784210-88-4
RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.
Formula:
C29H35N7O4
Purity:
97.29% - 99.91%
Color and Shape:
Solid
Molecular weight:
545.63
Ref: TM-T2378
| 1mg | 47.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 264.00 € | ||
| 50mg | 399.00 € | ||
| 100mg | 557.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
AG-494
CAS:133550-35-3
AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.
Formula:
C16H12N2O3
Purity:
98.69%
Color and Shape:
Solid
Molecular weight:
280.28
Ref: TM-T4205
| 10mg | 44.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 117.00 € | ||
| 100mg | 198.00 € | ||
| 200mg | 283.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
PHA-767491
CAS:845714-00-3
PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and …
Formula:
C12H11N3O
Purity:
100.00% - 99.49%
Color and Shape:
Solid
Molecular weight:
213.24
Ref: TM-T6206
| 2mg | 35.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 225.00 € | ||
| 100mg | 404.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
ON-013100
CAS:865783-95-5
ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit …
Formula:
C19H22O7S
Purity:
98.27%
Color and Shape:
Solid
Molecular weight:
394.44
Ref: TM-T16391
| 1mg | 50.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 283.00 € | ||
| 100mg | 425.00 € | ||
| 200mg | 602.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
MLS-573151
CAS:10179-57-4
MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).
Formula:
C21H19N3O2S
Purity:
98.80%
Color and Shape:
Solid
Molecular weight:
377.46
Ref: TM-T22106
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 383.00 € | ||
| 200mg | 545.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Senexin A
CAS:1366002-50-7
Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd …
Formula:
C17H14N4
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
274.32
Ref: TM-T5673
| 1mg | 37.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 340.00 € | ||
| 100mg | 485.00 € | ||
| 200mg | 657.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SU-9516
CAS:666837-93-0
SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.
Formula:
C13H11N3O2
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
241.25
Ref: TM-T8819
| 1mg | 90.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 248.00 € | ||
| 50mg | 321.00 € | ||
| 100mg | 419.00 € | ||
| 500mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
Formula:
C23H29ClN8O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
469.02
Ref: TM-T4417
| 1mg | 59.00 € | ||
| 2mg | 85.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 728.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
FIT-039
CAS:1113044-49-7
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin …
Formula:
C17H18FN3S
Purity:
98.61%
Color and Shape:
Solid
Molecular weight:
315.41
Ref: TM-T8972
| 5mg | 37.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 101.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 239.00 € | ||
| 200mg | 354.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
ON123300
CAS:1357470-29-1
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).
Formula:
C24H27N7O
Purity:
99.22% - 99.53%
Color and Shape:
Solid
Molecular weight:
429.52
Ref: TM-T6920
| 1mg | 47.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 265.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 628.00 € | ||
| 500mg | 1,301.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Ribociclib
CAS:1211441-98-3
Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50:10/39 nM).
Formula:
C23H30N8O
Purity:
100% - 99.96%
Color and Shape:
Solid
Molecular weight:
434.54
Ref: TM-T6199
| 2mg | 43.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 116.00 € | ||
| 100mg | 168.00 € | ||
| 500mg | 420.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Milciclib
CAS:802539-81-7
Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. …
Formula:
C25H32N8O
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
460.57
Ref: TM-T6081
| 1mg | 51.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 603.00 € | ||
| 100mg | 905.00 € | ||
| 200mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
YKL-5-124
CAS:1957203-01-8
YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 …
Formula:
C28H33N7O3
Purity:
99.5%
Color and Shape:
Solid
Molecular weight:
515.61
Ref: TM-T22461
| 1mg | 96.00 € | ||
| 2mg | 135.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 341.00 € | ||
| 25mg | 548.00 € | ||
| 50mg | 782.00 € | ||
| 100mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 225.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
