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Microtubule Associated

Microtubule Associated

Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.

Found 285 products of "Microtubule Associated"

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  • CymitQuimica logo
    Targetmol
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    Anticancer agent 139

    Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high
    Formula:C16H12F3N3O
    Color and Shape:Solid
    Molecular weight:319.28

    Ref: TM-T78780

  • Phomopsin A
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    Phomopsin A

    CAS:
    Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.
    Formula:C36H45ClN6O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:789.23

    Ref: TM-T12448

  • KIF18A-IN-2
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    KIF18A-IN-2

    CAS:
    <p>KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.</p>
    Formula:C25H34N4O5S2
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:534.69

    Ref: TM-T60026

  • 7-Epi-10-oxo-docetaxel
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    7-Epi-10-oxo-docetaxel

    CAS:
    7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.
    Formula:C43H51NO14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:805.86

    Ref: TM-T19163

  • Vinzolidine
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    Vinzolidine

    CAS:
    Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.
    Formula:C48H58ClN5O9
    Color and Shape:Solid
    Molecular weight:884.46

    Ref: TM-T88270

  • CymitQuimica logo
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    Tubulin inhibitor 50

    Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.
    Formula:C16H10ClFN2O2
    Color and Shape:Solid
    Molecular weight:316.04148

    Ref: TM-T207405

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    Tubulin inhibitor 45

    Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.
    Formula:C19H18N2O2S
    Molecular weight:338.1089

    Ref: TM-T210235

  • PhosTAC7
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    PhosTAC7

    CAS:
    PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.
    Formula:C58H87ClN2O17
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:1119.77

    Ref: TM-T77934

  • Tirbanibulin dihydrochloride
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    Tirbanibulin dihydrochloride

    CAS:
    Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).
    Formula:C26H31Cl2N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:504.45

    Ref: TM-T15674

  • Trifluralin
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    Trifluralin

    CAS:
    <p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>
    Formula:C13H16F3N3O4
    Purity:99.84%
    Color and Shape:Yellow-Orange Crystalline Solid
    Molecular weight:335.28

    Ref: TM-T17163

  • Ombrabulin hydrochloride
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    Ombrabulin hydrochloride

    CAS:
    <p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>
    Formula:C21H27ClN2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.9

    Ref: TM-T16386

  • colchiceine
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    colchiceine

    CAS:
    colchiceine has a wide range of applications in life science related research.
    Formula:C21H23NO6
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:385.41

    Ref: TM-TC0037

  • BSc3094
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    BSc3094

    CAS:
    BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.
    Formula:C17H12N6O3S
    Color and Shape:Solid
    Molecular weight:380.38

    Ref: TM-T41102

  • Amiprofos methyl
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    Amiprofos methyl

    CAS:
    Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.
    Formula:C11H17N2O4PS
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:304.30

    Ref: TM-T35486

  • Oryzalin
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    Oryzalin

    CAS:
    Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.
    Formula:C12H18N4O6S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:346.36

    Ref: TM-T65381

  • TTBK1-IN-1
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    TTBK1-IN-1

    CAS:
    TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.
    Formula:C18H19N5O2
    Color and Shape:Solid
    Molecular weight:337.38

    Ref: TM-T40348

  • Avanbulin
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    Avanbulin

    CAS:
    Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.
    Formula:C20H17N7O2
    Color and Shape:Solid
    Molecular weight:387.39

    Ref: TM-T21317

  • TN-16
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    TN-16

    CAS:
    TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)
    Formula:C19H18N2O2
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:306.36

    Ref: TM-T7800

  • Vindesine sulfate
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    Vindesine sulfate

    CAS:
    Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.
    Formula:C43H57N5O11S
    Purity:97.51%
    Color and Shape:Amorphous Solid
    Molecular weight:852

    Ref: TM-T22455

  • N-Phenylbenzylamine
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    N-Phenylbenzylamine

    CAS:
    A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
    Formula:C13H13N
    Purity:98.75%
    Color and Shape:Colorless To Pale Yellow Crystalline Powder
    Molecular weight:183.25

    Ref: TM-T0651