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c-Myc

c-Myc

c-Myc inhibitors target the c-Myc protein, a transcription factor that plays a pivotal role in cell growth, proliferation, and apoptosis. c-Myc regulates the expression of numerous genes involved in the cell cycle and is often overexpressed in various cancers, leading to uncontrolled cell proliferation and tumor growth. Inhibiting c-Myc can disrupt these processes, inducing cell cycle arrest and apoptosis in cancer cells. c-Myc inhibitors are important tools in cancer research and therapeutic development. At CymitQuimica, we offer a wide range of high-quality c-Myc inhibitors to support your research in oncology, cell cycle regulation, and transcriptional control.

Found 69 products of "c-Myc"

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  • c-Myc inhibitor 8

    CAS:
    <p>c-Myc inhibitor 8 suppresses cell growth in various cancers and is used in research.</p>
    Formula:C19H12BrClF3NO3S2
    Color and Shape:Solid
    Molecular weight:538.79
  • m-Se3

    CAS:
    <p>m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].</p>
    Formula:C29H23IN2Se
    Purity:98%
    Color and Shape:Solid
    Molecular weight:605.37
  • SYHA1815

    CAS:
    <p>SYHA1815, an orally active RET inhibitor (IC50=0.9 nmol/L), demonstrates antitumor activity. It exhibits greater selectivity for RET over KDR (IC50=15.9 nmol/L). SYHA1815 operates by downregulating c-Myc, arresting the G1 cell cycle, and inhibiting RET-driven cell proliferation.</p>
    Formula:C27H26ClF4N5O
    Color and Shape:Solid
    Molecular weight:547.98
  • KI-CDK9d-32

    CAS:
    <p>KI-CDK9d-32 is a CDK9 PROTAC degrader with a DC50 of 0.89 nM. It facilitates the ubiquitination and degradation of CDK9, inhibits the MYC pathway, and disrupts nucleolar homeostasis. KI-CDK9d-32 demonstrates anticancer activity.</p>
    Formula:C39H45N9O4
    Color and Shape:Solid
    Molecular weight:703.83
  • c-Myc inhibitor 4


    <p>Potent oral c-Myc inhibitor 4 reduces the proto-oncogene linked to tumor development.</p>
    Formula:C26H33FN6O3
    Color and Shape:Solid
    Molecular weight:496.58
  • BRD4 Inhibitor-40

    CAS:
    <p>BRD4 Inhibitor-40 (Compound 23) functions as an inhibitor of BRD, effectively targeting BRD4-BD1, BRD4-BD2, BRD2-BD1, and BRD2-BD2, with IC50 values of 16.1, 142.18, 29.35, and 302.35 nM, respectively. It modulates the expression of c-Myc and p21, induces cell cycle arrest in the G1 phase, and inhibits Pkd1-deficient (PN) renal cystic epithelial cells. Additionally, it prevents renal cyst formation in both Madin-Darby canine kidney and embryonic kidney cyst models, and demonstrates renal cyst inhibition activity in mouse models.</p>
    Formula:C27H32N8O
    Color and Shape:Solid
    Molecular weight:484.596
  • MY05

    CAS:
    <p>MY05 selectively targets c-MYC within cells and disrupts the interaction between MYC and MAX. It binds to intracellular c-MYC, modulating its thermal stability, reducing the transcriptional targets of c-MYC, and exhibiting anticancer activity (TNBC, triple-negative breast cancer).</p>
    Formula:C19H11ClN4O
    Color and Shape:Solid
    Molecular weight:346.77
  • JY-3-094

    CAS:
    <p>JY-3-094 is a selective Myc inhibitor that targets the hydrophobic domain of Myc and inhibits the formation of the Myc-Max heterodimer, with an IC50 of 33 μM, and can be used for cancer research.</p>
    Formula:C13H8N4O5
    Purity:98.72%
    Color and Shape:Solid
    Molecular weight:300.23
  • β-catenin-IN-8

    CAS:
    <p>β-catenin-IN-8 (Compound 25) is an inhibitor of β-catenin. It effectively lowers the levels of both β-catenin and c-Myc proteins and suppresses Wnt target genes (Fgf20 and Sall4). Additionally, β-catenin-IN-8 exhibits anticancer activity against colorectal cancer and possesses metabolic stability.</p>
    Formula:C15H12ClN3O2S
    Color and Shape:Solid
    Molecular weight:333.79