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c-Myc

c-Myc

c-Myc inhibitors target the c-Myc protein, a transcription factor that plays a pivotal role in cell growth, proliferation, and apoptosis. c-Myc regulates the expression of numerous genes involved in the cell cycle and is often overexpressed in various cancers, leading to uncontrolled cell proliferation and tumor growth. Inhibiting c-Myc can disrupt these processes, inducing cell cycle arrest and apoptosis in cancer cells. c-Myc inhibitors are important tools in cancer research and therapeutic development. At CymitQuimica, we offer a wide range of high-quality c-Myc inhibitors to support your research in oncology, cell cycle regulation, and transcriptional control.

Found 69 products of "c-Myc"

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  • CSI86


    <p>CSI86 is a PROTAC degrader targeting MYC, exhibiting antiproliferative activity (IC50: 13-18 μM).</p>
    Formula:C48H50F9N7O7S
    Color and Shape:Solid
    Molecular weight:1040
  • WBC100

    CAS:
    <p>WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathway</p>
    Formula:C25H33NO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:459.53
  • Anticancer agent 263


    <p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>
    Formula:C13H20N2O6
    Color and Shape:Solid
    Molecular weight:300.308
  • c-Myc inhibitor 7

    CAS:
    <p>c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.</p>
    Formula:C35H30N6O5
    Color and Shape:Soild
    Molecular weight:614.65
  • Anticancer agent 84

    CAS:
    <p>Anticancer agent 84 inhibits c-MYC transcription by stabilizing G4 structures, aiding cancer research.</p>
    Formula:C57H67N7O9
    Color and Shape:Solid
    Molecular weight:994.18
  • VGN50


    <p>VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.</p>
    Formula:C121H218N46O32
    Molecular weight:2827.68453
  • c-Myc inhibitor 13


    <p>c-Myc inhibitor13 (compound A6) is an inhibitor of c-MYC transcription. It selectively stabilizes c-MYCG4 and inhibits G4-related c-MYC transcription.</p>
    Formula:C30H39N9O
    Molecular weight:541.32776
  • Cotylenin A

    CAS:
    <p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>
    Formula:C33H50O11
    Color and Shape:Solid
    Molecular weight:622.744
  • H122


    <p>H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)</p>
    Formula:C45H45ClFN5O8
    Color and Shape:Solid
    Molecular weight:838.319
  • PROTAC LZK-IN-1

    CAS:
    <p>PROTAC LZK-IN-1 (Compound 21A) is a PROTAC molecule that targets the degradation of LZK (leucine zipper kinase, encoded by MAP3K13). At a concentration of 10 μM, PROTAC LZK-IN-1 facilitates the degradation of LZK and inhibits the expression of p53 and c-MYC, leading to reduced viability of global head and neck squamous cell carcinoma (HNSCC) cell lines. This compound is applicable in anticancer research.</p>
    Formula:C51H64F2N10O5S
    Color and Shape:Solid
    Molecular weight:967.18
  • KL4-219A


    <p>KL4-219A is a selective covalent degrader of the MYC, inhibiting MYC transcriptional activity and degrading MYC in a proteasome-dependent manner .</p>
    Formula:C20H24N2O2S
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:356.48
  • VPC-70063

    CAS:
    <p>VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.</p>
    Formula:C16H12F6N2S
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:378.34
  • sAJM589

    CAS:
    <p>sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels and inhibiting the cellular proliferation.</p>
    Formula:C16H10N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:246.26
  • IRES-C11

    CAS:
    <p>IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.</p>
    Formula:C13H11Cl2NO4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:316.14
  • Mycro 3

    CAS:
    <p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>
    Formula:C24H17ClF2N6O4
    Purity:99.51% - 99.61%
    Color and Shape:Solid
    Molecular weight:526.88
  • Saxagliptin

    CAS:
    <p>Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.</p>
    Formula:C18H25N3O2
    Purity:99.17% - 99.95%
    Color and Shape:Solid
    Molecular weight:315.41
  • (S)-10-Hydroxycamptothecin

    CAS:
    <p>(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.</p>
    Formula:C20H16N2O5
    Purity:99.09% - 99.81%
    Color and Shape:Solid
    Molecular weight:364.35
  • Mollugin

    CAS:
    <p>Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.</p>
    Formula:C17H16O4
    Purity:99.87% - ≥95%
    Color and Shape:Solid
    Molecular weight:284.31
  • ML327

    CAS:
    <p>ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).</p>
    Formula:C19H18N4O4
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:366.37
  • 10074-G5

    CAS:
    <p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>
    Formula:C18H12N4O3
    Purity:99.51% - 99.67%
    Color and Shape:Solid
    Molecular weight:332.31