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ROCK

ROCK

ROCK (Rho-associated protein kinase) inhibitors target ROCK kinases, which are involved in the regulation of the cytoskeleton, cell shape, and motility. ROCK plays a significant role in the control of cell division, particularly in processes such as cytokinesis. Inhibiting ROCK can lead to changes in cell cycle dynamics, cell motility, and apoptosis, making these inhibitors valuable in cancer research, neurobiology, and cardiovascular studies. At CymitQuimica, we provide a selection of high-quality ROCK inhibitors to support your research in cell biology, cytoskeletal dynamics, and disease mechanisms.

Found 62 products of "ROCK"

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  • ROCK-IN-7
    Targetmol
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    ROCK-IN-7

    CAS:
    ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].
    Formula:C17H17N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:327.4

    Ref: TM-T79080

    5mg
    To inquire
    50mg
    To inquire
  • ROCK-IN-9
    Targetmol
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    ROCK-IN-9

    CAS:
    ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM.
    Formula:C20H20FN5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:381.4

    Ref: TM-T79833

    5mg
    To inquire
    50mg
    To inquire
  • ROCK2-IN-6 hydrochloride
    Targetmol
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    ROCK2-IN-6 hydrochloride

    CAS:
    ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂，适用于研究ROCK介导的疾病、自身免疫性病症与炎症。
    Formula:C26H22ClF2N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:521.95

    Ref: TM-T78205

    2mg
    278.00€
  • Chroman 1
    Targetmol
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    Chroman 1

    CAS:
    Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).
    Formula:C24H28N4O4
    Purity:99.67% - 99.84%
    Color and Shape:Solid
    Molecular weight:436.5

    Ref: TM-T14960

    1mg
    73.00€
    5mg
    160.00€
    10mg
    250.00€
    25mg
    430.00€
    50mg
    645.00€
    100mg
    888.00€
    1mL*10mM (DMSO)
    173.00€
  • ROCK2-IN-2
    Targetmol
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    ROCK2-IN-2

    CAS:
    ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).
    Formula:C18H12N6OS
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:360.39

    Ref: TM-T12747

    1mg
    50.00€
    5mg
    111.00€
    10mg
    177.00€
    25mg
    304.00€
    50mg
    447.00€
    100mg
    692.00€
    200mg
    888.00€
    1mL*10mM (DMSO)
    136.00€
  • ROCK-IN-1
    Targetmol
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    ROCK-IN-1

    CAS:
    ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological
    Formula:C20H18FN3O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:335.37

    Ref: TM-T13419

    1mg
    115.00€
    5mg
    274.00€
  • H-1152 dihydrochloride
    Targetmol
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    H-1152 dihydrochloride

    CAS:
    H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.
    Formula:C16H23Cl2N3O2S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:392.34

    Ref: TM-T35328

    1mg
    60.00€
    5mg
    135.00€
    10mg
    215.00€
    25mg
    415.00€
    50mg
    655.00€
    100mg
    888.00€
    1mL*10mM (DMSO)
    147.00€
  • ROCK-IN-11
    Targetmol
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    ROCK-IN-11

    CAS:
    ROCK-IN-11 (example 94) is an effective inhibitor of ROCK1 and ROCK2, with an IC50 of ≤ 5 μM, and plays a significant role in cancer research.
    Formula:C22H20N4O4S
    Color and Shape:Solid
    Molecular weight:436.484

    Ref: TM-T204468

    10mg
    To inquire
    50mg
    To inquire
  • Rhodblock 1a
    Targetmol
    + Info

    Rhodblock 1a

    CAS:

    Rhodblock 1a is an inhibitor of the Rho kinase signaling pathway, which disrupts the localization and function of proteins within the Rho pathway. This interference hinders the proper formation of the cleavage furrow during cell division, leading to some cells either failing to form the cleavage furrow or forming a ruptured furrow, resulting in binucleated cells. Rhodblock 1a can be utilized for investigating cell division mechanisms and holds potential for research into cardiovascular diseases and cancer.

    Formula:C20H16N2O2
    Color and Shape:Solid
    Molecular weight:316.353

    Ref: TM-T206882

    10mg
    To inquire
    50mg
    To inquire
  • Zelasudil
    Targetmol
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    Zelasudil

    CAS:
    Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.
    Formula:C22H21F2N7O
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:437.445

    Ref: TM-T69665

    1mg
    96.00€
    5mg
    172.00€
    10mg
    261.00€
    25mg
    444.00€
    50mg
    620.00€
    100mg
    865.00€
    1mL*10mM (DMSO)
    178.00€
  • ROCK2-IN-6
    Targetmol
    + Info

    ROCK2-IN-6

    CAS:

    ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].

    Formula:C26H21F2N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:485.49

    Ref: TM-T79832

    ne
    Discontinued
    5mg
    Discontinued
    50mg
    Discontinued
    Discontinued product
  • ROCK-IN-6
    Targetmol
    + Info

    ROCK-IN-6

    CAS:

    ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1

    Formula:C19H19N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:477.45

    Ref: TM-T79077

    5mg
    Discontinued
    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product