
HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 169 products of "HSP"
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HM03 trihydrochloride
CAS:<p>HM03 trihydrochloride is a potent and selective inhibitor of HSPA5, also known as Bip or Grp78. It exhibits anticancer activity.</p>Formula:C26H30Cl4N4O2Color and Shape:SolidMolecular weight:572.35DTHIB
CAS:<p>DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.</p>Formula:C13H9ClFN3O3Purity:98.86% - 99.29%Color and Shape:SolidMolecular weight:309.68TRC051384 HCl
CAS:<p>TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.</p>Formula:C25H32ClN5O4Purity:97.55%Color and Shape:SolidMolecular weight:502.01KNK437
CAS:<p>KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).</p>Formula:C13H11NO4Purity:98.90%Color and Shape:SolidMolecular weight:245.23Ganetespib
CAS:<p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>Formula:C20H20N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:364.4Pimitespib
CAS:<p>Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).</p>Formula:C25H26N8OPurity:99.22% - 99.49%Color and Shape:SolidMolecular weight:454.53HSP27 inhibitor J2
CAS:<p>HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of</p>Formula:C13H12O4SPurity:99.51%Color and Shape:SolidMolecular weight:264.3Palmitic acid
CAS:<p>Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.</p>Formula:C16H32O2Purity:99.17% - 99.67%Color and Shape:White Crystalline Scales SolidMolecular weight:256.42Grp94 Inhibitor-1
CAS:<p>Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).</p>Formula:C22H28N2O2Purity:97.02%Color and Shape:SolidMolecular weight:352.47Geldanamycin
CAS:<p>Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.</p>Formula:C29H40N2O9Purity:97.59% - 99.27%Color and Shape:Yellow To Orange PowderMolecular weight:560.64Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Formula:C31H43N3O8Purity:99.07% - 99.83%Color and Shape:Dark Purple SolidMolecular weight:585.69Paeoniflorin
CAS:<p>Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.</p>Formula:C23H28O11Purity:96.9% - 97.43%Color and Shape:White Fine PowderMolecular weight:480.46Apoptozole
CAS:<p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>Formula:C33H25F6N3O3Purity:99.75%Color and Shape:SolidMolecular weight:625.56HA15
CAS:<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Formula:C23H22N4O3S2Purity:99.77% - 99.86%Color and Shape:SolidMolecular weight:466.58Eupalinolide A
CAS:<p>Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.</p>Formula:C24H30O9Purity:98.82% - 99.22%Color and Shape:SolidMolecular weight:462.49KW-2478
CAS:<p>KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.</p>Formula:C30H42N2O9Purity:98.68% - 99.52%Color and Shape:SolidMolecular weight:574.66Feretoside
CAS:<p>Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).</p>Formula:C17H24O11Purity:99.85%Color and Shape:SolidMolecular weight:404.37VER-49009
CAS:<p>VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).</p>Formula:C19H18ClN3O4Purity:99.36% - 99.99%Color and Shape:SolidMolecular weight:387.82DDO-5936
CAS:<p>DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.</p>Formula:C25H29N5O4SPurity:99.81%Color and Shape:SolidMolecular weight:495.59NVP-HSP990
CAS:<p>NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).</p>Formula:C20H18FN5O2Purity:98.03% - 99.32%Color and Shape:SolidMolecular weight:379.39
