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HSP

HSP

HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.

Found 169 products of "HSP"

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  • HM03 trihydrochloride

    CAS:
    <p>HM03 trihydrochloride is a potent and selective inhibitor of HSPA5, also known as Bip or Grp78. It exhibits anticancer activity.</p>
    Formula:C26H30Cl4N4O2
    Color and Shape:Solid
    Molecular weight:572.35
  • DTHIB

    CAS:
    <p>DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.</p>
    Formula:C13H9ClFN3O3
    Purity:98.86% - 99.29%
    Color and Shape:Solid
    Molecular weight:309.68
  • TRC051384 HCl

    CAS:
    <p>TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.</p>
    Formula:C25H32ClN5O4
    Purity:97.55%
    Color and Shape:Solid
    Molecular weight:502.01
  • KNK437

    CAS:
    <p>KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).</p>
    Formula:C13H11NO4
    Purity:98.90%
    Color and Shape:Solid
    Molecular weight:245.23
  • Ganetespib

    CAS:
    <p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>
    Formula:C20H20N4O3
    Purity:98% - 99.95%
    Color and Shape:Solid
    Molecular weight:364.4
  • Pimitespib

    CAS:
    <p>Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).</p>
    Formula:C25H26N8O
    Purity:99.22% - 99.49%
    Color and Shape:Solid
    Molecular weight:454.53
  • HSP27 inhibitor J2

    CAS:
    <p>HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of</p>
    Formula:C13H12O4S
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:264.3
  • Palmitic acid

    CAS:
    <p>Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms.</p>
    Formula:C16H32O2
    Purity:99.17% - 99.67%
    Color and Shape:White Crystalline Scales Solid
    Molecular weight:256.42
  • Grp94 Inhibitor-1

    CAS:
    <p>Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).</p>
    Formula:C22H28N2O2
    Purity:97.02%
    Color and Shape:Solid
    Molecular weight:352.47
  • Geldanamycin

    CAS:
    <p>Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.</p>
    Formula:C29H40N2O9
    Purity:97.59% - 99.27%
    Color and Shape:Yellow To Orange Powder
    Molecular weight:560.64
  • Tanespimycin

    CAS:
    <p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>
    Formula:C31H43N3O8
    Purity:99.07% - 99.83%
    Color and Shape:Dark Purple Solid
    Molecular weight:585.69
  • Paeoniflorin

    CAS:
    <p>Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.</p>
    Formula:C23H28O11
    Purity:96.9% - 97.43%
    Color and Shape:White Fine Powder
    Molecular weight:480.46
  • Apoptozole

    CAS:
    <p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>
    Formula:C33H25F6N3O3
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:625.56
  • HA15

    CAS:
    <p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>
    Formula:C23H22N4O3S2
    Purity:99.77% - 99.86%
    Color and Shape:Solid
    Molecular weight:466.58
  • Eupalinolide A

    CAS:
    <p>Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.</p>
    Formula:C24H30O9
    Purity:98.82% - 99.22%
    Color and Shape:Solid
    Molecular weight:462.49
  • KW-2478

    CAS:
    <p>KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.</p>
    Formula:C30H42N2O9
    Purity:98.68% - 99.52%
    Color and Shape:Solid
    Molecular weight:574.66
  • Feretoside

    CAS:
    <p>Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).</p>
    Formula:C17H24O11
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:404.37
  • VER-49009

    CAS:
    <p>VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).</p>
    Formula:C19H18ClN3O4
    Purity:99.36% - 99.99%
    Color and Shape:Solid
    Molecular weight:387.82
  • DDO-5936

    CAS:
    <p>DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.</p>
    Formula:C25H29N5O4S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:495.59
  • NVP-HSP990

    CAS:
    <p>NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).</p>
    Formula:C20H18FN5O2
    Purity:98.03% - 99.32%
    Color and Shape:Solid
    Molecular weight:379.39