HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 180 products of "HSP"
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HSP90-IN-22
CAS:HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM inFormula:C25H30N4O3Purity:98%Color and Shape:SolidMolecular weight:434.53Bimoclomol
CAS:Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.Formula:C14H20ClN3O2Color and Shape:SolidMolecular weight:297.78Hsp90-IN-15
CAS:Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.Formula:C23H27F3N4Color and Shape:SolidMolecular weight:416.48AMP-PCP disodium
CAS:AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM.Formula:C11H16N5Na2O12P3Purity:99.32% - 99.32%Color and Shape:SolidMolecular weight:549.17JG-231
CAS:JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.
Formula:C22H18BrCl2N3OS4Purity:99.79%Color and Shape:SolidMolecular weight:619.47SNX0723
CAS:SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.Formula:C22H26FN3O3Purity:99.85%Color and Shape:SolidMolecular weight:399.46Ref: TM-T28824
1mg85.00€5mg178.00€10mg299.00€25mg485.00€50mg665.00€100mg892.00€500mgTo inquire1mL*10mM (DMSO)195.00€Arimoclomol
CAS:Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Formula:C14H20ClN3O3Purity:99.15%Color and Shape:SolidMolecular weight:313.78Iroxanadine
CAS:Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation inFormula:C14H20N4OPurity:98.04% - 99.04%Color and Shape:SolidMolecular weight:260.33KU-177
CAS:KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Formula:C27H23NO8Purity:96.92% - 98.54%Color and Shape:SolidMolecular weight:489.47Flavokawain 1i
CAS:Flavokawain 1i, a derivative of chalcones flavokawain A, flavokawain B, and flavokawain C, exhibits anticancer and antiviral properties.Formula:C21H18O4Color and Shape:SolidMolecular weight:334.37MAO A/HSP90-IN-2
CAS:MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90.Formula:C25H31ClN2O4Purity:98%Color and Shape:SolidMolecular weight:458.98GRP78-IN-2
CAS:GRP78-IN-2 inhibits surface GRP78, showing anti-angiogenic and anti-cancer properties, sparing normal cells.Formula:C29H29NO6Color and Shape:SolidMolecular weight:487.54Iroxanadine sulfate
CAS:Iroxanadine sulfate is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.Formula:C14H22N4O5SColor and Shape:SolidMolecular weight:358.41MAO A/HSP90-IN-1
CAS:MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.Formula:C24H29ClN2O4Purity:98%Color and Shape:SolidMolecular weight:444.95Colletofragarone A2
CAS:Colletofragarone A2 from Colletotrichum sp. blocks mutant p53 and HSP90, aiding cancer treatment.Formula:C22H26O6Color and Shape:SolidMolecular weight:386.44YM-08
CAS:YM-08 (Compound 7a), a brain-penetrant SIRT2 inhibitor, exhibits an IC50 of 19.9 μM. Additionally, it acts as an inhibitor of Hsp70 [1].Formula:C19H17N3OS2Purity:98%Color and Shape:SolidMolecular weight:367.49HSP90-IN-29
CAS:HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].Formula:C19H20ClN3O4Color and Shape:SolidMolecular weight:389.83HSP90-IN-27
CAS:HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].Formula:C18H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:343.44BX-2819
CAS:BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .Formula:C21H24N4O4SPurity:98%Color and Shape:SolidMolecular weight:428.51HSP90-IN-19
CAS:HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.Formula:C29H38O7Purity:98%Color and Shape:SolidMolecular weight:498.61
