HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 176 products for "HSP".
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Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Formula:C32H48N4O8·HClPurity:99.85% - 99.94%Color and Shape:Purple SolidMolecular weight:653.21Feretoside
CAS:Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).Formula:C17H24O11Purity:99.85%Color and Shape:SolidMolecular weight:404.37Ref: TM-TQ0280
1mg73.00€5mg167.00€1mL*10mM (DMSO)190.00€10mg260.00€25mg440.00€50mg628.00€100mg872.00€200mg1,153.00€Apoptozole
CAS:Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.Formula:C33H25F6N3O3Purity:99.75%Color and Shape:SolidMolecular weight:625.56Ref: TM-T3293
2mg34.00€5mg48.00€1mL*10mM (DMSO)63.00€10mg79.00€25mg130.00€50mg222.00€100mg331.00€200mg489.00€VER-50589
CAS:VER-50589 is a potent HSP90 inhibitor.Formula:C19H17ClN2O5Purity:99.96% - >99.99%Color and Shape:SolidMolecular weight:388.8Ref: TM-T2258
1mg39.00€5mg92.00€1mL*10mM (DMSO)92.00€10mg150.00€25mg250.00€50mg384.00€100mg557.00€200mg787.00€Teprenone
CAS:Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).Formula:C23H38OPurity:99.1% - 99.96%Color and Shape:SolidMolecular weight:330.55Alvespimycin
CAS:Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.Formula:C32H48N4O8Purity:99.88%Color and Shape:SolidMolecular weight:616.75Calenduloside E
CAS:Calenduloside E (Silphioside F) exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and byFormula:C36H56O9Purity:96.16% - 98.99%Color and Shape:SolidMolecular weight:632.82HSP90-IN-20
CAS:HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.Formula:C26H32N4O4Color and Shape:SolidMolecular weight:464.56HSP90-IN-12
CAS:VAC, a potent anti-cancer vibsanin A analog, inhibits cell proliferation and affects HSP90 protein levels.Formula:C25H36O4Color and Shape:SolidMolecular weight:400.55YM-01 Tosylate
CAS:YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.Formula:C27H27N3O4S3Color and Shape:SolidMolecular weight:553.72Displurigen
CAS:Displurigen is an inhibitor of ATPase activity of HSP70.Formula:C15H10O4SPurity:98%Color and Shape:SolidMolecular weight:286.36BrCaQ
CAS:6BrCaQ inhibits TRAP1, has antiproliferative effects, and is used in 6BrCaQ-TPP synthesis.Formula:C18H15BrN2O3Color and Shape:SolidMolecular weight:387.23PU3
CAS:PU3 is an inhibitor of Hsp90.Formula:C19H25N5O3Purity:98%Color and Shape:SolidMolecular weight:371.43SEW84
CAS:SEW84, an Aha1-stimulated Hsp90 inhibitor, has an IC50 of 0.3 μM, aiding protein deposition disease research.Formula:C19H14F4N4OSColor and Shape:SolidMolecular weight:422.4HSP90-IN-14
CAS:HSP90-IN-14 inhibits Hsp90 (Kd=0.26 μM) and fights influenza A/H3N2, A/H1N1, B with EC50 of 2.6, 3.9, 17 μM in MDCK cells.Formula:C14H8Cl2N4O4SColor and Shape:SolidMolecular weight:399.21CH5164840
CAS:CH5164840 is an HSP90 inhibitor; IC50=4.1 nM; oral active; degrades client proteins; cancer research tool.Formula:C19H23N5O2SPurity:99.80%Color and Shape:White SolidMolecular weight:385.48Hsp90-Cdc37-IN-1
CAS:Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.Formula:C43H57FN2O6SPurity:98%Color and Shape:SolidMolecular weight:748.99Vibsanin A
CAS:Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.Formula:C25H38O4Color and Shape:SolidMolecular weight:402.57YM-1
CAS:YM-1 is an HSP70 inhibitor; promotes client protein degradation; disrupts protein folding; cancer research tool.Formula:C20H20ClN3OS2Purity:99.58%Color and Shape:Red SolidMolecular weight:417.98BIIB028
CAS:BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.Formula:C19H21ClN5O5PColor and Shape:SolidMolecular weight:465.83Retaspimycin
CAS:Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).Formula:C31H45N3O8Purity:98%Color and Shape:SolidMolecular weight:587.7KUNB31
CAS:KUNB31 is a potent and selective inhibitor of Hsp90β.Formula:C19H18N2O3Color and Shape:SolidMolecular weight:322.36Hsp90-IN-17
CAS:Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.Formula:C21H20N4O7Color and Shape:SolidMolecular weight:440.41Heat Shock Protein Inhibitor II
CAS:Hsp inhibitor II, an active benzylidene lactam, blocks inducible Hsp synthesis, reduces tumor thermotolerance, and enhances AmB effects on A. fumigatus.Formula:C12H11NO3Color and Shape:SolidMolecular weight:217.22SW02
CAS:SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).Formula:C19H23BrN2O5Color and Shape:SolidMolecular weight:439.3PU24FCl
CAS:PU24FCl is a specific inhibitor of tumor Hsp90.Formula:C20H21ClFN5O3Color and Shape:SolidMolecular weight:433.86BMS-358233
CAS:BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.Formula:C25H25ClN6O2SColor and Shape:SolidMolecular weight:509.02CH5138303
CAS:CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.Formula:C19H18ClN5O2SPurity:98%Color and Shape:SolidMolecular weight:415.9JG-48
CAS:JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.Formula:C20H16F3N3OS2Color and Shape:SolidMolecular weight:435.49CCT251236
CAS:CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.Formula:C32H32N4O5Purity:98.82% - 99.89%Color and Shape:White SolidMolecular weight:552.62Ref: TM-T14905
1mg34.00€5mg105.00€1mL*10mM (DMSO)130.00€10mg200.00€25mg414.00€50mg662.00€100mg1,054.00€Icapamespib HCl
CAS:Icapamespib (PU-HZ151) is an HSP90 inhibitor; EC50 of 5 nM, logD of 2.37; targets epichaperomes, effective in cells, mice, and humans.Formula:C19H25Cl2IN6O2SColor and Shape:SolidMolecular weight:599.31CH5015765
CAS:CH5015765: potent, selective HSP90 inhibitor with high affinity and antitumor effects in human cancer mouse models.Formula:C16H13ClN4OSColor and Shape:SolidMolecular weight:344.82Grp94-IN-2
CAS:Grp94-IN-2 is a inhibitor of Grp94.Formula:C22H23ClN2O5Color and Shape:SolidMolecular weight:430.88BF844
CAS:BF844 chemical counters USH3-induced hearing loss by transporting mutated CLRN1 to cell membranes, effectively preserving hearing in vivo.Formula:C21H19ClN4OColor and Shape:SolidMolecular weight:378.85STA-2842
CAS:STA-2842 is an inhibitor of heat shock protein 90 (HSP90).Formula:C29H38N6O5Color and Shape:SolidMolecular weight:550.65EC 144
CAS:EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.Formula:C21H24ClN5O2Color and Shape:SolidMolecular weight:413.9Retaspimycin Hydrochloride
CAS:Retaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).Formula:C31H46ClN3O8Purity:98%Color and Shape:SolidMolecular weight:624.17MPC-3100
CAS:MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1].Formula:C22H25BrN6O4SColor and Shape:SolidMolecular weight:549.44HSP90-IN-22
CAS:HSP90-IN-22 is a potent HSP90 inhibitor; client protein degrader; blocks oncogenic signaling; cancer research tool.Formula:C25H30N4O3Purity:99.90%Color and Shape:SolidMolecular weight:434.53Bimoclomol
CAS:Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.Formula:C14H20ClN3O2Color and Shape:SolidMolecular weight:297.78Hsp90-IN-15
CAS:Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.Formula:C23H27F3N4Color and Shape:SolidMolecular weight:416.48SNX0723
CAS:SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.Formula:C22H26FN3O3Purity:99.85%Color and Shape:White SolidMolecular weight:399.46Ref: TM-T28824
500mgTo inquire1mg85.00€5mg178.00€1mL*10mM (DMSO)195.00€10mg299.00€25mg485.00€50mg665.00€100mg892.00€Arimoclomol
CAS:Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Formula:C14H20ClN3O3Purity:99.15%Color and Shape:SolidMolecular weight:313.78Iroxanadine
CAS:Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation inFormula:C14H20N4OPurity:98.04% - 99.04%Color and Shape:SolidMolecular weight:260.33Colletofragarone A2
CAS:Colletofragarone A2 from Colletotrichum sp. blocks mutant p53 and HSP90, aiding cancer treatment.Formula:C22H26O6Color and Shape:SolidMolecular weight:386.44MAO A/HSP90-IN-2
CAS:MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90.Formula:C25H31ClN2O4Purity:98%Color and Shape:SolidMolecular weight:458.98KU-177
CAS:KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Formula:C27H23NO8Purity:96.92% - 98.54%Color and Shape:SolidMolecular weight:489.47YM-08
CAS:YM-08 (Compound 7a), a brain-penetrant SIRT2 inhibitor, exhibits an IC50 of 19.9 μM. Additionally, it acts as an inhibitor of Hsp70 [1].Formula:C19H17N3OS2Purity:98%Color and Shape:SolidMolecular weight:367.49HSP90-IN-19
CAS:HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.Formula:C29H38O7Purity:98%Color and Shape:SolidMolecular weight:498.61MAO A/HSP90-IN-1
CAS:MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.Formula:C24H29ClN2O4Purity:98%Color and Shape:SolidMolecular weight:444.95
