Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2612 products of "Chromatin/Epigenetics"
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PRMT5-IN-10
CAS:PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex.Formula:C13H17N5O4Color and Shape:SolidMolecular weight:307.31Depudecin
CAS:Depudecin, a polyketide from Alternaria brassicicola, has an 11-carbon chain with two epoxides and six stereocenters, inhibits HDAC, and is anti-angiogenic.Formula:C11H16O4Color and Shape:SolidMolecular weight:212.24NSD3-IN-2
CAS:NSD3-IN-2: Potent NSD3 inhibitor, IC50 17.97μM, halts NSCLC growth (H460, H1299, H1650) with anticancer effects.Formula:C17H15N5OSColor and Shape:SolidMolecular weight:337.4MAT2A-IN-4
CAS:MAT2A-IN-4 can be used for the cancer research that is an inhibitor of methionine adenosyltransferase 2A (MAT2A)[1].Formula:C18H16ClN3OColor and Shape:SolidMolecular weight:325.79NSD3-IN-3
CAS:"NSD3-IN-3, a potent anticancer agent, inhibits NSD3 (IC50: 1.86 μM) and hampers H460 lung cancer cell growth."Formula:C15H17N5O2SColor and Shape:SolidMolecular weight:331.39SYK/JAK-IN-1
CAS:SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.Formula:C24H26N8O3Color and Shape:SolidMolecular weight:474.52HDAC-IN-43
CAS:HDAC-IN-43: potent HDAC 1/3/6 inhibitor (IC50: 82 nM HDAC1, 45 nM HDAC3, 24 nM HDAC6); weak PI3K/mTOR (IC50: 3.6μM, 3.7μM); anti-proliferative.Formula:C22H28N6O4Color and Shape:SolidMolecular weight:440.5NC-III-49-1
CAS:NC-III-49-1: potent BET inhibitor, binds BRD4/BRDT, inhibits cell growth, reduces c-Myc expression.Formula:C44H50N4O11S2Color and Shape:SoildMolecular weight:875.02HDAC-IN-44
CAS:HDAC-IN-44 is an HDAC inhibitor (IC50: 61.2 nM) with strong anti-cancer effects.Formula:C26H27BrN4O4Color and Shape:SolidMolecular weight:539.42SIRT1-IN-2
CAS:SIRT1-IN-2 (compound 3h) is a potent and selective inhibitor of SIRT1 (silent information regulator 1) with an IC 50 of 1.6 μM [1].Formula:C13H15ClN2OColor and Shape:SolidMolecular weight:250.72BET bromodomain inhibitor 2
CAS:BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).Formula:C23H30N2O5SColor and Shape:SolidMolecular weight:446.56GDC-4379
CAS:GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Formula:C21H18ClF2N7O3Color and Shape:SolidMolecular weight:489.86HDAC6-IN-10
CAS:HDAC6-IN-10 is a potent HDAC6 inhibitor with 0.73 nM IC50, highly selective, and hinders multiple myeloma cell growth.Formula:C21H20N4O4Color and Shape:SolidMolecular weight:392.41HDAC6-IN-46
CAS:HDAC6-IN-46 (compound 12) is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 6.2 nM. It is utilized in research related to Alzheimer's disease.Formula:C26H21N3O4Color and Shape:SolidMolecular weight:439.46MAT2A-IN-5
CAS:MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.Formula:C17H12ClF3N2OColor and Shape:SolidMolecular weight:352.74SIRT6-IN-1
CAS:SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.Formula:C19H14N4O5SColor and Shape:SolidMolecular weight:410.4EZH2-IN-7
CAS:EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.Formula:C31H37D2N5O3SColor and Shape:SolidMolecular weight:563.755-Aza-4'-thio-2'-deoxycytidine
CAS:5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].Formula:C8H12N4O3SColor and Shape:SolidMolecular weight:244.27G9a-IN-2
CAS:G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).Formula:C30H42N4O4Color and Shape:SolidMolecular weight:522.68FAK/aurora kinase-IN-1
CAS:FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Formula:C23H24ClN7O3Color and Shape:SolidMolecular weight:481.93HDAC-IN-30
CAS:HDAC-IN-30 is a potent HDAC inhibitor targeting HDAC1, 2, 3, 6, and 8 with strong antitumor efficacy.
Formula:C22H23N5O3Color and Shape:SolidMolecular weight:405.45ML753286
CAS:ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.Formula:C20H25N3O3Purity:98%Color and Shape:SolidMolecular weight:355.43EZM 2302
CAS:EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).Cost-effective and quality-assured.Formula:C29H37ClN6O5Purity:97.47% - ≥98%Color and Shape:SolidMolecular weight:585.09NSC 698600
CAS:NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].Formula:C14H12N2O2SColor and Shape:SolidMolecular weight:272.32SPC-180002
CAS:SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.Formula:C18H23NO4Purity:98%Color and Shape:SolidMolecular weight:317.38HPCG
CAS:HPCG is an inhibitor of HIF-1α prolyl hydroxylase.Formula:C8H8N2O4Color and Shape:SolidMolecular weight:196.16Sirtuin modulator 4
CAS:Sirtuin modulator 4 inhibits SIRT1 (EC50: 51-100 μM), may extend cell life and prevent diseases like diabetes and cancer.Formula:C18H10N2O2SColor and Shape:SolidMolecular weight:318.35KU-0058684
CAS:KU-0058684 is a potent PARP and DNA-PK inhibitors.Formula:C19H14FN3O3Color and Shape:SolidMolecular weight:351.33ZIKV-IN-2
CAS:ZIKV-IN-2 blocks ZIKV replication, is a strong NS5 MTase inhibitor (IC50: 38.86 μM), and aids Zika virus research.Formula:C39H42O4Color and Shape:SolidMolecular weight:574.75iBRD4-BD1
CAS:iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.Formula:C29H30F3N5OColor and Shape:SolidMolecular weight:521.58GNA002
CAS:GNA002 is a highly potent, specific, and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor (IC50: 1.1 μM).Formula:C42H55NO8Purity:98%Color and Shape:SolidMolecular weight:701.89CPI-905
CAS:CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.Formula:C18H20N2O5Color and Shape:SolidMolecular weight:344.36ZLD1039
CAS:ZLD1039, an oral EZH2 inhibitor, shows strong PRC2 inhibition at low nanomolar IC50s, and halts breast cancer growth and spread.Formula:C36H48N6O3Purity:99.5%Color and Shape:SolidMolecular weight:612.8Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Formula:C13H11ClFN5Color and Shape:SolidMolecular weight:291.71UMB-32
CAS:UMB-32: Potent, selective BRD4 inhibitor, Kd 550 nM, IC50 637 nM, also targets TAF1.Formula:C21H23N5OColor and Shape:SolidMolecular weight:361.44Bromodomain inhibitor-10
CAS:Bromodomain inhibitor-10 (compound 128) suppresses BRD4-1/2 with Kd 15 nM/2.5 μM and curbs IL12p40 production.Formula:C20H20N4O3Color and Shape:SolidMolecular weight:364.4FNDR-20123 free base
CAS:FNDR-20123 is a safe, oral first-in-class anti-malarial HDAC inhibitor with low IC50s against Plasmodium and human HDACs.Formula:C21H23N5O2Color and Shape:SolidMolecular weight:377.44CAY10669
CAS:CAY10669 inhibits PCAF (IC50 = 662 μM), is twice as potent as anacardic acid, and reduces H4 acetylation in HepG2 cells at 30-60 μM.Formula:C20H22O4Color and Shape:SolidMolecular weight:326.39OM-137
CAS:OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Formula:C13H14N4O3SColor and Shape:SolidMolecular weight:306.34UNC6212 (Kme2)
UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM .Formula:C39H53N7O11Color and Shape:SolidMolecular weight:795.88TC-E 5001
CAS:dual tankyrase (TNKS) inhibitorFormula:C20H19N5O3SPurity:98%Color and Shape:SolidMolecular weight:409.46BET-BAY 002 (S enantiomer)
CAS:The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).Formula:C22H18ClN5OPurity:98%Color and Shape:SolidMolecular weight:403.86Bromodomain IN-1
CAS:Bromodomain IN-1 is an inhibitor of Bromodomain.Formula:C22H23ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:458.96BAY-598 R-isomer
CAS:BAY-598 R-isomer, a SMYD2-selective inhibitor, is the R-enantiomer of BAY589, not targeting PAR1.Formula:C22H20Cl2F2N6O3Color and Shape:SolidMolecular weight:525.34JAK3/BTK-IN-2
CAS:JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Formula:C25H32N8O2Purity:99.64% - 99.87%Color and Shape:SolidMolecular weight:476.57HDAC/CK2-IN-1
CAS:HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Formula:C15H18Br4N4O2Color and Shape:SolidMolecular weight:605.95PARP-2/1-IN-2
CAS:PARP-2/1-IN-2, Veliparib's enantiomer, inhibits PARP-1/2 (Ki: 5/2 nM) with 3 nM EC50 in cell assay.Formula:C13H16N4OColor and Shape:SolidMolecular weight:244.29HDAC/NAMPT-IN-1
CAS:HDAC/NAMPT-IN-1 (compound 39h) simultaneously inhibits HDAC and NAMPT, exhibiting IC 50 values ranging from 0.72 to 37081 nM for HDAC and 1618 nM for NAMPT [1].Formula:C19H21N5O2Color and Shape:SolidMolecular weight:351.4Tyk2-IN-5
CAS:Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).Formula:C21H19FN8O2Purity:98%Color and Shape:SolidMolecular weight:434.43DDO-2093 dihydrochloride
DDO-2093 dihydrochloride: potent MLL1-WDR5 inhibitor, IC50=8.6 nM, Kd=11.6 nM, antitumor.Formula:C29H39Cl3FN9O3Color and Shape:SolidMolecular weight:687.04UNC0379 TFA
CAS:UNC0379 TFA inhibits SETD8 (IC50: 7.3 μM), selective for 15+ methyltransferases.Formula:C25H36F3N5O4Color and Shape:SolidMolecular weight:527.589IACS-9571
CAS:IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).Formula:C32H42N4O8SPurity:98%Color and Shape:SolidMolecular weight:642.76YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formula:C21H22ClFN2OPurity:99.65%Color and Shape:SolidMolecular weight:372.86MI-2-2
CAS:MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.Formula:C17H20F3N5S2Purity:99.65%Color and Shape:SolidMolecular weight:415.5CX-6258
CAS:CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.Formula:C26H24ClN3O3Purity:97.46%Color and Shape:SolidMolecular weight:461.94Ref: TM-T1834
1mg34.00€5mg75.00€10mg101.00€25mg197.00€50mg295.00€100mg447.00€200mg623.00€1mL*10mM (DMSO)77.00€Furamidine dihydrochloride
CAS:Furamidine dihydrochloride is a cell-permeable, selective PRMT1 inhibitor that also binds AT-rich DNA. It blocks proliferation in leukemia cell lines.Formula:C18H18Cl2N4OPurity:98.16%Color and Shape:SolidMolecular weight:377.27F-amidine
CAS:F-amidine is a bioavailable irreversible PAD4 inactivator.Formula:C14H19FN4O2Color and Shape:SolidMolecular weight:294.32KD 5170
CAS:KD 5170, a pan inhibitor of histone deacetylases (HDACs), demonstrates widespread antitumor activity both in vitro and in vivo [1].Formula:C20H25N3O5S2Color and Shape:SolidMolecular weight:451.56PI3K/Akt/CREB activator 1
CAS:PI3K/Akt/CREB activator 1 (AE-18) is an iNOS inhibitor that can be used to study vascular dementia and Parkinson's.Formula:C19H15F4NO3Color and Shape:SolidMolecular weight:381.32JAK3-IN-1
CAS:JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Formula:C26H30ClN7O2Color and Shape:SolidMolecular weight:508.02TAK-418
CAS:TAK-418 is an orally active LSD1/KDM1A inhibitor with a 2.9 nM IC50, potential for autism therapy.Formula:C17H25ClN2O2SPurity:99.69%Color and Shape:SolidMolecular weight:356.91Ref: TM-T39252
1mg131.00€5mg313.00€10mg494.00€25mg1,009.00€50mg1,359.00€100mg1,818.00€200mg2,457.00€1mL*10mM (DMSO)366.00€TUL01101
CAS:TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.Formula:C22H25F2N5O2Color and Shape:SolidMolecular weight:429.46LSD1-IN-13
CAS:LSD1-IN-13, an oral LSD1 blocker (IC50: 24.43 nM), boosts CD86 (EC50: 470 nM), and triggers AML cell line differentiation.Formula:C23H29N3O2SColor and Shape:SolidMolecular weight:411.56SIRT5 inhibitor 4
CAS:SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.Formula:C18H15N3O4SPurity:99.97%Color and Shape:SolidMolecular weight:369.39WD2000-012547
CAS:WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).Formula:C17H14N2OPurity:98%Color and Shape:SolidMolecular weight:262.31BI-9321
CAS:BI-9321: Selective NSD3-PWWP1 antagonist, Kd 166 nM. Inactive against NSD2-PWWP1/NSD3-PWWP2.Formula:C22H21FN4Purity:98%Color and Shape:SolidMolecular weight:360.43SIRT5 inhibitor 6
CAS:SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.Formula:C21H28N6O4SPurity:99.84%Color and Shape:SolidMolecular weight:460.55SHP2/HDAC-IN-1
CAS:SHP2/HDAC-IN-1: dual SHP2/HDAC inhibitor, IC50: 20.4 nM/25.3 nM, boosts antitumor immunity, aids cancer immunotherapy research.Formula:C34H35Cl2N7O3Color and Shape:SolidMolecular weight:660.59BiBET
CAS:BiBET is a potent, selective, bivalent inhibitor of BET bromodomains.Formula:C26H30N10O3Color and Shape:SolidMolecular weight:530.58NSD3-IN-1
CAS:NSD3-IN-1, a histone methyltransferase NSD3 inhibitor, demonstrates an IC50 of 28.58 μM.Formula:C13H13N5OSColor and Shape:SolidMolecular weight:287.34PF-249
CAS:PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.Formula:C17H16ClN3O3Purity:97.01%Color and Shape:SolidMolecular weight:345.78Ref: TM-T24626
1mg46.00€5mg92.00€10mg147.00€25mg236.00€50mg344.00€100mg482.00€200mg662.00€1mL*10mM (DMSO)100.00€Izencitinib
CAS:Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.Formula:C22H26N8Purity:99.82%Color and Shape:SolidMolecular weight:402.50Ref: TM-T35898
1mg84.00€5mg177.00€10mg281.00€25mg567.00€50mg888.00€100mg1,431.00€200mg1,963.00€1mL*10mM (DMSO)195.00€ACY-957
CAS:ACY-957: Oral HDAC1/2 inhibitor (IC50: HDAC1=7nM, HDAC2=18nM, HDAC3=1300nM); inactive on HDAC4/5/6/7/8/9.Formula:C24H23N5OSPurity:99.79%Color and Shape:SolidMolecular weight:429.54Ref: TM-T10245
1mg90.00€2mg136.00€5mg230.00€10mg281.00€25mg432.00€50mg612.00€100mg802.00€1mL*10mM (DMSO)251.00€β-NF-JQ1
CAS:β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins.Formula:C45H42ClN5O6SPurity:97.58% - 99.15%Color and Shape:SolidMolecular weight:816.36EB-47
CAS:EB-47 imitates NAD+, spans nicotinamide to adenosine sites, inhibits PARP-1 (IC50: 45 nM) and is less effective on ARTD5 (IC50: 410 nM).Formula:C24H27N9O6Purity:99.81%Color and Shape:SolidMolecular weight:537.53PARP10-IN-2
CAS:PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and
Formula:C14H10N2O2Purity:99.27%Color and Shape:SolidMolecular weight:238.24JAK-STAT-IN-1
CAS:JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.Formula:C21H21N5O2Purity:99.59%Color and Shape:SolidMolecular weight:375.42CD532
CAS:CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Formula:C26H25F3N8OPurity:99.99%Color and Shape:SolidMolecular weight:522.52LSD1-IN-20
CAS:LSD1-IN-20: Dual LSD1/G9a inhibitor, Ki 0.44/0.68 μM; hampers THP-1, MDA-MB-231 cell growth with IC50 0.51/1.60 μM at 72h.Formula:C27H38N6O2Purity:97.17% - 99.57%Color and Shape:SolidMolecular weight:478.63ZEN-3411
CAS:ZEN-3411 is an BET inhibitor that inhibits BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2) and suppresses the growth of tumor cells overproducing BET proteins.Formula:C21H20N4O2Purity:97.51% - 98.84%Color and Shape:SolidMolecular weight:360.41ZEN-2759
CAS:ZEN-2759 is a potent BET small molecule inhibitor of BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).Formula:C17H16N2O2Purity:99.36%Color and Shape:SolidMolecular weight:280.32TM2-115
CAS:TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].Formula:C28H38N6O2Purity:97.67%Color and Shape:SolidMolecular weight:490.64ACY-1083
CAS:ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.Formula:C17H18F2N4O2Purity:99.19% - 99.43%Color and Shape:SolidMolecular weight:348.35Ref: TM-T10244
1mg144.00€5mg295.00€10mg504.00€25mg795.00€50mg1,108.00€100mg1,494.00€500mg2,997.00€1mL*10mM (DMSO)326.00€R 59-022 hydrochloride
CAS:R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.
Formula:C27H27ClFN3OSPurity:97.7%Color and Shape:SolidMolecular weight:496.04SIRT5 inhibitor 1
CAS:SIRT5 inhibitor 1 targets human Sirtuin 5 deacylase, with an IC50 of 0.11 μM, linked to aging diseases.Formula:C31H39FN6O6S2Purity:97.8%Color and Shape:SolidMolecular weight:674.81Ref: TM-T12921
1mg138.00€2mg197.00€5mg334.00€10mg502.00€25mg884.00€50mg1,288.00€100mg1,728.00€1mL*10mM (DMSO)442.00€Bobcat339 hydrochloride
CAS:Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.Formula:C16H13Cl2N3OPurity:99.22%Color and Shape:SolidMolecular weight:334.2Ref: TM-T61012
2mg34.00€5mg50.00€10mg80.00€25mg152.00€50mg236.00€100mg353.00€200mg517.00€1mL*10mM (DMSO)55.00€SS-208
CAS:SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.Formula:C13H11Cl2N3O4Purity:99.69%Color and Shape:SolidMolecular weight:344.15Butyrolactone 3
CAS:Butyrolactone 3 (MB-3) is a Gcn5 inhibitor with weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and can be used in cancer.Formula:C9H12O4Purity:98.99% - 99.5%Color and Shape:SolidMolecular weight:184.19KRH102140
CAS:KRH102140 is a PHD2 activator that reduces angiogenesis by inhibiting HIF-1alpha, used in cardiovascular disease research.Formula:C25H24FNOPurity:98.31% - 99.61%Color and Shape:SolidMolecular weight:373.46NSC668394
CAS:NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.Formula:C17H12Br2N2O3Purity:99.29% - 99.29%Color and Shape:SolidMolecular weight:452.1ZEN-3862
CAS:ZEN-3862, a BET inhibitor, blocks BRD4(BD1) at 0.16 μM & BRD4(BD2) at 0.13 μM; usable in PROTACs for BRD4 degradation.Formula:C19H17FN2O3Purity:97.1%Color and Shape:SolidMolecular weight:340.35HDAC8-IN-20a
CAS:HDAC8-IN-20a (HDAC8 inhibitor-20a) is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM.Formula:C15H15NO4Purity:98.24% - 99.22%Color and Shape:SolidMolecular weight:273.28Ref: TM-T24133
1mg173.00€5mg424.00€10mg585.00€25mg873.00€50mg1,134.00€100mg1,468.00€200mg1,963.00€1mL*10mM (DMSO)380.00€CARM1-IN-1
CAS:CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.Formula:C26H21Br2NO3Purity:98.24%Color and Shape:SolidMolecular weight:555.26Ref: TM-T10682L
1mg34.00€5mg84.00€10mg120.00€25mg236.00€50mg385.00€100mg600.00€200mg837.00€1mL*10mM (DMSO)92.00€CPUY074020
CAS:CPUY074020 is a potent and orally bioavailable inhibitor of histone methyltransferase G9a (IC50: 2.18 μM) with anti-proliferative activity.Formula:C25H28N4O2Purity:98.64%Color and Shape:SolidMolecular weight:416.52Ref: TM-T10882
1mg71.00€5mg147.00€10mg205.00€25mg319.00€50mg450.00€100mg587.00€200mg803.00€1mL*10mM (DMSO)159.00€MAT2A-IN-9
CAS:MAT2A-IN-9, a 2-oxoquinazoline, inhibits MAT2A with antitumor effects on lymphomas and solid cancers.Formula:C14H8ClF3N4OPurity:99.17%Color and Shape:SolidMolecular weight:340.69CMP-5
CAS:CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.Formula:C21H21N3Purity:98.68%Color and Shape:SolidMolecular weight:315.41Ref: TM-T10850
1mg44.00€5mg92.00€10mg137.00€25mg225.00€50mg334.00€100mg494.00€500mg1,054.00€1mL*10mM (DMSO)101.00€Butyzamide
CAS:Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.Formula:C29H32Cl2N2O5SPurity:99.39% - 99.83%Color and Shape:SoildMolecular weight:591.55Ref: TM-T67894
1mg149.00€5mg253.00€10mg371.00€25mg573.00€50mg862.00€100mg1,305.00€200mg1,755.00€1mL*10mM (DMSO)329.00€BRD4 Inhibitor-20
CAS:BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity.
Formula:C18H18N2O4SPurity:99.84%Color and Shape:SolidMolecular weight:358.41Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.
Formula:C27H21N3O3Purity:99.22%Color and Shape:SolidMolecular weight:435.47ML192
CAS:ML192 (CID1434953) is a selective GPR55 ligand antagonist.Formula:C20H22N4O2SPurity:99.17%Color and Shape:SolidMolecular weight:382.48Ref: TM-T33452
1mg34.00€5mg71.00€10mg104.00€25mg172.00€50mg249.00€100mg350.00€200mg480.00€1mL*10mM (DMSO)92.00€
