Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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ZL0590
CAS:<p>ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.</p>Formula:C23H27F3N4O4SPurity:99.77%Color and Shape:SoildMolecular weight:512.55OKI-006
CAS:<p>OKI-006 is an oral HDAC inhibitor with potential for cancer research, derived from largazole.</p>Formula:C21H30N4O5S2Color and Shape:SolidMolecular weight:482.62JHDM-IN-1
CAS:<p>JHDM-IN-1 inhibits JHDMs; IC50: 3.4 μM JMJD2C, 4.3 μM JMJD2A, 5.9 μM JMJD2E, 10 μM PHF8, 43 μM JMJD3.</p>Formula:C27H29N3O6Color and Shape:SolidMolecular weight:491.54GSK040
CAS:<p>GSK040: Potent BET BD2 inhibitor, pIC50 8.3, 5000x selectivity over BD1, for oncology & immunology research.</p>Formula:C29H34N4O4Color and Shape:SolidMolecular weight:502.6SMD-3040 TFA
<p>SMD-3040 TFA is a selective SMARCA2 degrader comprising SMARCA2/4 ligands, a linker, and VHL ligands, utilized in PROTAC drug synthesis.</p>Purity:98%Color and Shape:Odour SolidPROTAC BRD4 Degrader-19
CAS:<p>PROTAC BRD4 Degrader-19 (compound 176) is a proteolysis-targeting chimera (PROTAC) designed to specifically degrade the BRD4 protein, offering potential utility</p>Formula:C44H38N8O5S2Color and Shape:SolidMolecular weight:822.95C 21
CAS:<p>PRMT1 inhibitor, IC50=1.8μM; 5x more selective than PRMT6; >250x over PRMT3, CARM1.</p>Formula:C90H161ClN36O24Purity:98%Color and Shape:SolidMolecular weight:2166.94GSK8573
CAS:<p>GSK8573 is an inactive control compound for GSK2801. GSK8573 has binding activity to BRD9 (Kd of 1.04 μM).</p>Formula:C20H21NO3Purity:99.81%Color and Shape:SolidMolecular weight:323.39BRD7-IN-1 free base
CAS:<p>BRD7-IN-1, a BI7273 derivative, transforms into PROTAC VZ185 (targets BRD7/9 with 4.5/1.8 nM DC50s) via a VHL linker.</p>Formula:C22H26N4O3Purity:98%Color and Shape:SolidMolecular weight:394.47dBAZ2
<p>dBAZ2 is a pioneering PROTAC degrader targeting BAZ2A and BAZ2B, with DC50 values of 180 nM for BAZ2A and 250 nM for BAZ2B.</p>Formula:C54H64FN11O5S2Color and Shape:SolidMolecular weight:1030.29HDAC-IN-68 hydrochloride
<p>HDAC-IN-68 (hydrochloride) (Compound 29) is an HDACs inhibitor with an IC50 value of 0.04 μM and induces microtubule fragmentation by activating katanin, a microtubule-severing protein. It is applicable in cancer research.</p>Formula:C27H25ClN8O6Molecular weight:592.15856MNK/PIM-IN-1
CAS:<p>MNK/PIM-IN-1 is a novel dual inhibitor targeting both MNK and PIM pathways, characterized by its favorable pharmacokinetic profile.</p>Formula:C27H27FN6O2Color and Shape:SolidMolecular weight:486.551TNKS-2-IN-2
CAS:<p>TNKS-2-IN-2 is a TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the study of colon cancer lung cancer and breast cancer.</p>Formula:C26H23N3O6Purity:99.45%Color and Shape:SoildMolecular weight:473.48LT-630
<p>LT-630 is an inhibitor of HDAC6. It alleviates liver damage by reducing oxidative stress injury.</p>Formula:C19H17FN4O3Molecular weight:368.128472-Methylquinazolin-4-ol
CAS:<p>Compound 1769-24-0 is a natural product for research related to life sciences. The catalog number is TPL0186 and the CAS number is 1769-24-0.</p>Formula:C9H8N2OPurity:99.98%Color and Shape:SolidMolecular weight:160.17α-Hydroxyglutaric Acid
CAS:<p>α-Hydroxyglutaric Acid is a natural product for research related to life sciences. The catalog number is T36624 and the CAS number is 2889-31-8.</p>Formula:C5H8O5Color and Shape:SolidMolecular weight:148.114CD532 hydrochloride
<p>CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.</p>Color and Shape:SolidHistone H3K9me3 (1-15) TFA
<p>Histone H3K9me3 (1-15) (H3(1-15)K9me3) TFA is used as a substrate. This post-translational modification (PTM) of histone H3K9me3 is indicative of heterochromatin surrounding the centromere.</p>Formula:C66H124N25O21·xC2HF3O2RJW100
CAS:<p>RJW100 is a potent LRH-1 & SF-1 agonist with pEC50 of 6.6 & 7.5, also activates miR-200c promoter.</p>Formula:C28H34OPurity:99.15%Color and Shape:SolidMolecular weight:386.57DNMT1/HDAC-IN-1
<p>DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory effects specifically on HDAC1 (HDAC1:IC50=0.05 μM), a major HDAC isoform that interacts with DNMT1 across multiple protein complexes involved in the transcriptional silencing of TSGs. This compound has been shown to remodel the tumor immune microenvironment and induce tumor regression, effectively reversing cancer-specific epigenetic abnormalities.</p>Color and Shape:Odour Solid
