Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2611 products of "Chromatin/Epigenetics"
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Nicotinamide riboside tartrate
CAS:NRT is an oral NAD+ precursor, boosts NAD+, activates SIRT1/3, provides vitamin B3, enhances metabolism, and may mitigate Alzheimer's.Formula:C15H20N2O11Color and Shape:SolidMolecular weight:404.33dBET23
CAS:dBET23 is a BRD4 degrader.Formula:C43H45ClN8O9SColor and Shape:SolidMolecular weight:885.38HDAC6-IN-42
HDAC6-IN-42 (compound 2b) is an HDAC6 inhibitor with an IC50 of 0.009 μM, demonstrating significant anti-leukemia activity and synergistic effects with Decitabine, indicating its potential use in the research of Acute Myeloid Leukemia (AML).Formula:C24H28FN3O4Molecular weight:441.20638EPZ-719
CAS:EPZ-719 is a selective and orally available SETD2 inhibitor (IC50 = 0.005 μM), with anti-cancer activity, and can be used for hematological malignancies.Formula:C22H31FN4O3SPurity:99.95%Color and Shape:SolidMolecular weight:450.57Ref: TM-T40318
1mg177.00€5mg385.00€10mg618.00€25mg1,305.00€50mg2,088.00€100mg5,670.00€1mL*10mM (DMSO)383.00€PRMT1-IN-1
CAS:PRMT1-IN-1 is a PRMT1 inhibitor.
Formula:C20H7Br6NO5Color and Shape:SolidMolecular weight:820.702CPI-268456
CAS:CPI-268456 is a compound which has bioactive.Formula:C20H15Cl2N3O2Color and Shape:SolidMolecular weight:400.26PROTAC SMARCA2/4-degrader-29
CAS:PROTAC SMARCA2/4-degrader-29 (Compound I-279) serves as a degrader for the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. In A549 cells, this compound effectively degrades SMARCA2 with a DC50 value of less than 100 nM, and similarly degrades SMARCA4 in MV411 cells with a DC50 under 100 nM.Formula:C44H51N11O4Color and Shape:SolidMolecular weight:797.95ACBI2
CAS:ACBI2: potent, oral VHL PROTAC, EC50=7nM; degrades SMARCA2, DC50=1nM in RKO cells; for lung cancer research.Formula:C56H68BrFN8O5SColor and Shape:SolidMolecular weight:1064.16Bisindolylmaleimide XI hydrochloride
CAS:Bisindolylmaleimide XI hydrochloride (Ro 32-0432) is an orally active pan-PKC inhibitor that inhibits PKCα, PKCβI, PKCβII, and PKCγ.Formula:C28H29ClN4O2Purity:99.45%Color and Shape:SolidMolecular weight:489.01RX-37
CAS:RX-37, a potent BET inhibitor (Ki: 3.2-24.7 nM for BRD2/3/4), selectively hinders growth in leukemia cells with MLL1 gene rearrangement.Formula:C24H23N5O2Purity:98%Color and Shape:SolidMolecular weight:413.47HIF-PHD-IN-4
HIF-PHD-IN-4 (Compound 13) is an orally active PHD2 inhibitor with an IC50 of 100 nM. At a dose of 2 mg/kg, it effectively enhances G-CSF-induced mobilization of hematopoietic stem cells in mice. HIF-PHD-IN-4 is suitable for research in the oncology field.Color and Shape:Odour SolidTAS-119
CAS:TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95Formula:C23H22Cl2FN5O3Purity:99.65%Color and Shape:SolidMolecular weight:506.36Ref: TM-T34787
1mg97.00€5mg235.00€10mg378.00€25mg748.00€50mg1,169.00€100mg1,644.00€1mL*10mM (DMSO)261.00€Protein Kinase C (19-36)
CAS:Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.Formula:C93H159N35O24Purity:98%Color and Shape:SolidMolecular weight:2151.48R8-T198wt
CAS:Cell-permeable peptide blocking Pim-1 kinase, halts DU145 cell growth, causes G1 arrest and apoptosis, inert to RPWE-1 cells at 10-20 μM.Formula:C111H211N59O26SPurity:98%Color and Shape:SolidMolecular weight:2820.33HDAC11-IN-1
HDAC11-IN-1 (Compound 14-NC6OH) is a macrocyclic inhibitor that selectively targets HDAC11 with a Ki of 40 nM. It demonstrates effective cell permeability and suppresses the expression of YAP1 and SOX2.Formula:C43H63F3N6O6S2Color and Shape:SolidMolecular weight:881.12CARM1/IKZF3 ligand 1
CARM1/IKZF3 ligand 1 functions as an inhibitor of CARM1 and serves as a target protein ligand for the synthesis of PROTAC CARM1/IKZF3 degrader-1.Formula:C27H35ClN6O3Color and Shape:SolidMolecular weight:527.06Nicotinamide riboside malate
CAS:Orally active NAD+ booster, NR malate enhances metabolism, supports cognitive function, and is a vitamin B3 source.Formula:C15H20N2O10Color and Shape:SolidMolecular weight:388.33PIM-IN-1
CAS:PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC 50 = 61 nM; pS6, EC 50 = 71 nM).Formula:C15H18ClFN4OColor and Shape:SolidMolecular weight:324.78PARP/HDAC-IN-1
PARP/HDAC-IN-1 is a PARP and HDAC inhibitor that inhibits PARP1, PARP2, and HDAC1, and may be used to study pancreatic cancer.Formula:C36H32F2N6O3Purity:95.00%Color and Shape:SolidMolecular weight:634.67BBDDL2204
BBDDL2204 (compound 13) is a potent and selective covalent inhibitor of EZH2, demonstrating an IC50 of 2.5 nM against EZH2Y641F.Formula:C37H47N5O5SColor and Shape:SolidMolecular weight:673.32979
