Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2613 products of "Chromatin/Epigenetics"
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PROTAC PARP1 degrader
CAS:PROTAC PARP1 degrader suppresses MDA-MB-231 cells at 10 μM, IC50: 6.12 μM in 24h.Formula:C58H63Cl2N11O10Purity:98%Color and Shape:SolidMolecular weight:1145.1T-448
CAS:T-448 is a lysine-specific demethylase 1 inhibitor (IC50: 22 nM) that improves learning function in mice.T-448 can be used to study memory deficits.Formula:C19H22N4O3SPurity:97% - 98.63%Color and Shape:SolidMolecular weight:386.47JET-209
JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) valuesFormula:C46H47N9O6Purity:98%Color and Shape:SolidMolecular weight:821.92Atinvicitinib
CAS:Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.Formula:C16H17FN6O3Purity:99.36%Color and Shape:SolidMolecular weight:360.35Ref: TM-T39646
1mg138.00€1mL*10mM (DMSO)264.00€5mg334.00€10mg550.00€25mg1,063.00€50mg1,738.00€100mg2,547.00€2'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS:2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.Formula:C9H13ClFN3O4Purity:99.43%Color and Shape:SolidMolecular weight:281.67Pim-1/2 kinase inhibitor 1
CAS:Orally active Pim-1/2 inhibitor blocks kinase phosphorylation; used in prostate cancer research.Formula:C11H9NO3SPurity:99.78%Color and Shape:SolidMolecular weight:235.26PKC-θ inhibitor
CAS:PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.Formula:C20H25F3N6O3Purity:99.46%Color and Shape:SolidMolecular weight:454.45Ref: TM-T5423
1mg101.00€5mg236.00€1mL*10mM (DMSO)259.00€10mg313.00€25mg442.00€50mg580.00€100mg893.00€200mg1,198.00€HDAC-IN-4
CAS:HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Formula:C14H19Cl2N3O2SPurity:99.81%Color and Shape:White Crystalline SolidMolecular weight:364.29SIRT5 inhibitor 3
CAS:SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .Formula:C22H12FN3O4Purity:98%Color and Shape:SolidMolecular weight:401.35MS8511 hydrochloride
CAS:MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics.Formula:C28H42ClN5O3Color and Shape:SolidMolecular weight:532.12(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Formula:C39H72O5Color and Shape:SolidMolecular weight:620.99O6BTG-octylglucoside
CAS:O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).Formula:C24H34BrN5O7SPurity:98%Color and Shape:SolidMolecular weight:616.531,4-DPCA ethyl ester
CAS:1,4-DPCA ethyl ester is a form of 1,4-DPCA modified, which has potential anticancer activity based on growth inhibition assays with the mlh1 rad18 yeast strain.Formula:C15H12N2O3Purity:99.54%Color and Shape:SolidMolecular weight:268.27Ref: TM-T36796
2mg37.00€5mg54.00€1mL*10mM (DMSO)59.00€10mg90.00€25mg157.00€50mg256.00€100mg434.00€200mg623.00€Ilunocitinib
CAS:Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.Formula:C17H17N7O2SPurity:99.88%Color and Shape:SolidMolecular weight:383.43Ref: TM-T38571
1mg92.00€5mg230.00€1mL*10mM (DMSO)251.00€10mg356.00€25mg713.00€50mg1,189.00€100mg1,791.00€200mg2,412.00€GSK-J2
CAS:GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.Formula:C22H23N5O2Purity:97.55%Color and Shape:SolidMolecular weight:389.45Ref: TM-T11476
1mg34.00€5mg71.00€10mg92.00€1mL*10mM (DMSO)101.00€25mg157.00€50mg222.00€100mg329.00€200mg487.00€DA-3003-1
CAS:DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.Formula:C15H16ClN3O3Purity:99.27% - 99.79%Color and Shape:SolidMolecular weight:321.76CHZ868
CAS:CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Formula:C22H19F2N5O2Purity:99.38%Color and Shape:SolidMolecular weight:423.42BAY-850
CAS:BAY-850 is ainhibitor of adenosine triphosphatase family protein 2 that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.Formula:C38H44ClN5O3Purity:98% - 98%Color and Shape:SolidMolecular weight:654.24SIRT-IN-3
CAS:SIRT-IN-3: potent SIRT1 inhibitor (IC50=17μM), 4x selective over SIRT2, 14x over SIRT3 (IC50s: 74μM & 235μM).Formula:C13H12N2OColor and Shape:SolidMolecular weight:212.25
