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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2238 products of "Chromatin/Epigenetics"

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  • (R)-(-)-JQ1 Enantiomer

    CAS:
    <p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>
    Formula:C23H25ClN4O2S
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:456.99
  • JQEZ5

    CAS:
    <p>JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).</p>
    Formula:C30H38N8O2
    Purity:98.14% - ≥98%
    Color and Shape:Solid
    Molecular weight:542.68
  • Rucaparib hydrochloride

    CAS:
    <p>Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.</p>
    Formula:C19H19ClFN3O
    Color and Shape:Solid
    Molecular weight:359.83
  • WHI-P97

    CAS:
    <p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>
    Formula:C16H13Br2N3O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:455.1
  • NU1025

    CAS:
    <p>NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.</p>
    Formula:C9H8N2O2
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:176.17
  • XMD8-92

    CAS:
    <p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>
    Formula:C26H30N6O3
    Purity:98.21%
    Color and Shape:Solid
    Molecular weight:474.55
  • Rucaparib acetate

    CAS:
    <p>Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.</p>
    Formula:C21H22FN3O3
    Color and Shape:Solid
    Molecular weight:383.423
  • Phthalazinone pyrazole

    CAS:
    <p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>
    Formula:C18H15N5O
    Purity:97.03%
    Color and Shape:Solid
    Molecular weight:317.34
  • GN44028

    CAS:
    <p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>
    Formula:C18H15N3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:305.33
  • Menin-MLL inhibitor 20

    CAS:
    <p>Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.</p>
    Formula:C33H40N8O4
    Purity:97.77%
    Color and Shape:Solid
    Molecular weight:612.72
  • JQ-1 (carboxylic acid)

    CAS:
    <p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>
    Formula:C19H17ClN4O2S
    Purity:99.14% - 99.9%
    Color and Shape:Solid
    Molecular weight:400.88
  • Peficitinib

    CAS:
    <p>Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.</p>
    Formula:C18H22N4O2
    Purity:98.67% - 99.4%
    Color and Shape:Solid
    Molecular weight:326.39
  • Ethyl 3,4-dihydroxybenzoate

    CAS:
    <p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>
    Formula:C9H10O4
    Purity:99.88%
    Color and Shape:White Crystal Or Powder
    Molecular weight:182.17
  • 1,5-Isoquinolinediol

    CAS:
    <p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>
    Formula:C9H7NO2
    Purity:98.29% - 99.35%
    Color and Shape:Of White To White Powder
    Molecular weight:161.16
  • Ruboxistaurin

    CAS:
    <p>Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.</p>
    Formula:C28H28N4O3
    Color and Shape:Solid
    Molecular weight:468.55
  • Upadacitinib

    CAS:
    <p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>
    Formula:C17H19F3N6O
    Purity:98.96% - 99.94%
    Color and Shape:Solid
    Molecular weight:380.37
  • 666-15

    CAS:
    <p>666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.</p>
    Formula:C33H31Cl2N3O5
    Purity:99.41% - 99.88%
    Color and Shape:Solid
    Molecular weight:620.52
  • EB-47 dihydrochloride

    CAS:
    <p>EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).</p>
    Formula:C24H29Cl2N9O6
    Color and Shape:Solid
    Molecular weight:610.45
  • SC-43

    CAS:
    <p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>
    Formula:C21H13ClF3N3O2
    Purity:98.44%
    Color and Shape:Solid
    Molecular weight:431.8
  • Naphthol AS-E

    CAS:
    <p>Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.</p>
    Formula:C17H12ClNO2
    Purity:99.33%
    Color and Shape:Grey Solid Powder
    Molecular weight:297.74