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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2238 products of "Chromatin/Epigenetics"

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  • Momelotinib
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    Momelotinib

    CAS:
    <p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>
    Formula:C23H22N6O2
    Purity:97.47% - 99.56%
    Color and Shape:Solid
    Molecular weight:414.46

    Ref: TM-T1849

  • 6-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
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    6-Bromo-3-methyl-1,4-dihydroquinazolin-2-one

    CAS:
    <p>CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).</p>
    Formula:C9H9BrN2O
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:241.08

    Ref: TM-T8609

  • OF-1
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    OF-1

    CAS:
    <p>OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.</p>
    Formula:C17H18BrN3O4S
    Purity:98.55% - ≥95%
    Color and Shape:Solid
    Molecular weight:440.31

    Ref: TM-T2127

  • SNS-314
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    SNS-314

    CAS:
    <p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>
    Formula:C18H15ClN6OS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.93

    Ref: TM-T21298

  • Abrocitinib
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    Abrocitinib

    CAS:
    <p>Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).</p>
    Formula:C14H21N5O2S
    Purity:99.09% - 99.91%
    Color and Shape:Solid
    Molecular weight:323.41

    Ref: TM-TQ0037

  • ZM39923 hydrochloride
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    ZM39923 hydrochloride

    CAS:
    <p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>
    Formula:C23H25NO·HCl
    Purity:98.05%
    Color and Shape:Solid
    Molecular weight:367.91

    Ref: TM-T6145

  • PF 477736
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    PF 477736

    CAS:
    <p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>
    Formula:C22H25N7O2
    Purity:97.58% - 99.94%
    Color and Shape:Solid
    Molecular weight:419.48

    Ref: TM-T6028

  • GSK 690 Hydrochloride
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    GSK 690 Hydrochloride

    CAS:
    <p>GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.</p>
    Formula:C24H24ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:405.92

    Ref: TM-T11503

  • 653-47
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    653-47

    CAS:
    <p>653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).</p>
    Formula:C20H19ClN2O3
    Color and Shape:Solid
    Molecular weight:370.83

    Ref: TM-T8889

  • CPI-1205
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    CPI-1205

    CAS:
    <p>CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。</p>
    Formula:C27H33F3N4O3
    Purity:98.71% - 99.7%
    Color and Shape:Solid
    Molecular weight:518.57

    Ref: TM-T8510

  • JQ-1 (carboxylic acid)
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    JQ-1 (carboxylic acid)

    CAS:
    <p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>
    Formula:C19H17ClN4O2S
    Purity:99.14% - 99.9%
    Color and Shape:Solid
    Molecular weight:400.88

    Ref: TM-T5443

  • PF-CBP1
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    PF-CBP1

    CAS:
    <p>PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).</p>
    Formula:C29H36N4O3
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:488.62

    Ref: TM-T3973

  • Aurora kinase inhibitor-3
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    Aurora kinase inhibitor-3

    CAS:
    <p>Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,</p>
    Formula:C21H18F3N5O
    Purity:98.91%
    Color and Shape:Solid
    Molecular weight:413.4

    Ref: TM-T5524

  • Daphnetin
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    Daphnetin

    CAS:
    <p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>
    Formula:C9H6O4
    Purity:97.47% - 99.8%
    Color and Shape:Solid
    Molecular weight:178.14

    Ref: TM-T2851

  • WHI-P97
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    WHI-P97

    CAS:
    <p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>
    Formula:C16H13Br2N3O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:455.1

    Ref: TM-T4657

  • GN44028
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    GN44028

    CAS:
    <p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>
    Formula:C18H15N3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:305.33

    Ref: TM-T15396

  • TCS7010
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    TCS7010

    CAS:
    <p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>
    Formula:C31H31ClFN7O2
    Purity:98.49% - 99.62%
    Color and Shape:Solid
    Molecular weight:588.07

    Ref: TM-T6767

  • Olaparib
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    Olaparib

    CAS:
    <p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>
    Formula:C24H23FN4O3
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:434.46

    Ref: TM-T3015

  • XAV-939
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    XAV-939

    CAS:
    <p>XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).</p>
    Formula:C14H11F3N2OS
    Purity:97.47% - 99.67%
    Color and Shape:Solid
    Molecular weight:312.31

    Ref: TM-T1878

  • Pyridone 6
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    Pyridone 6

    CAS:
    <p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>
    Formula:C18H16FN3O
    Purity:97.1% - 98.74%
    Color and Shape:Solid
    Molecular weight:309.34

    Ref: TM-T3080