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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2242 products of "Chromatin/Epigenetics"

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  • A-966492

    CAS:
    <p>A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.</p>
    Formula:C18H17FN4O
    Purity:98.53% - 99.27%
    Color and Shape:Solid
    Molecular weight:324.35
  • GSK503

    CAS:
    <p>GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.</p>
    Formula:C31H38N6O2
    Purity:98% - 99.89%
    Color and Shape:Solid
    Molecular weight:526.67
  • PFI-4

    CAS:
    <p>PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.</p>
    Formula:C21H24N4O3
    Purity:99.53% - ≥95%
    Color and Shape:Solid
    Molecular weight:380.44
  • NI-57

    CAS:
    <p>NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).</p>
    Formula:C19H17N3O4S
    Purity:99.88% - >99.99%
    Color and Shape:Solid
    Molecular weight:383.42
  • Menin-MLL inhibitor MI-2

    CAS:
    <p>Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.</p>
    Formula:C18H25N5S2
    Purity:97.46%
    Color and Shape:Solid
    Molecular weight:375.55
  • Molibresib besylate

    CAS:
    <p>Molibresib besylate (GSK 525762C) is a BET protein family inhibitor used in the study of refractory hematologic malignant diseases.</p>
    Formula:C28H28ClN5O5S
    Purity:99.64% - 99.64%
    Color and Shape:Solid
    Molecular weight:582.07
  • Oroxylin A

    CAS:
    <p>Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.</p>
    Formula:C16H12O5
    Purity:98.72% - 99.55%
    Color and Shape:Solid
    Molecular weight:284.26
  • Tofacitinib

    CAS:
    <p>Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.</p>
    Formula:C16H20N6O
    Purity:99% - >99.99%
    Color and Shape:Solid
    Molecular weight:312.37
  • GSK126

    CAS:
    <p>GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).</p>
    Formula:C31H38N6O2
    Purity:98% - 99.67%
    Color and Shape:Solid
    Molecular weight:526.67
  • Seclidemstat

    CAS:
    <p>Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.</p>
    Formula:C20H23ClN4O4S
    Purity:98.28% - 99.76%
    Color and Shape:Solid
    Molecular weight:450.94
  • Veliparib dihydrochloride

    CAS:
    <p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>
    Formula:C13H18Cl2N4O
    Purity:98% - 99.81%
    Color and Shape:Solid
    Molecular weight:317.21
  • Remodelin

    CAS:
    <p>Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.</p>
    Formula:C15H14N4S
    Purity:99.39% - 99.83%
    Color and Shape:Solid
    Molecular weight:282.363
  • PT-2385

    CAS:
    <p>PT-2385 is a selective HIF-2α inhibitor (Kd&lt;50 nM).</p>
    Formula:C17H12F3NO4S
    Purity:98.91% - 99.55%
    Color and Shape:Solid
    Molecular weight:383.34
  • Venadaparib

    CAS:
    <p>Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.</p>
    Formula:C23H23FN4O2
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:406.45
  • RN-1 dihydrochloride

    CAS:
    <p>RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).</p>
    Formula:C23H31Cl2N3O2
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:452.42
  • Ruxolitinib

    CAS:
    <p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>
    Formula:C17H18N6
    Purity:99.4% - >99.99%
    Color and Shape:Solid
    Molecular weight:306.36
  • GSK2801

    CAS:
    <p>GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.</p>
    Formula:C20H21NO4S
    Purity:97.78% - 99.45%
    Color and Shape:Solid
    Molecular weight:371.45
  • 5-Methyl-2'-deoxycytidine

    CAS:
    <p>5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.</p>
    Formula:C10H15N3O4
    Purity:99.18% - 99.69%
    Color and Shape:Solid
    Molecular weight:241.24
  • 2-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one

    CAS:
    <p>2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.</p>
    Formula:C10H11NOS
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:193.27
  • 5-Fluoro-2'-deoxycytidine

    CAS:
    <p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>
    Formula:C9H12FN3O4
    Purity:97.91%
    Color and Shape:Fine White Powder
    Molecular weight:245.21