Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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(Z)-SMI-4a
CAS:<p>(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.</p>Formula:C11H6F3NO2SPurity:97.66% - 99.93%Color and Shape:SolidMolecular weight:273.23Oclacitinib
CAS:<p>Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000</p>Formula:C15H23N5O2SPurity:98% - 98.45%Color and Shape:White To Off-White SolidMolecular weight:337.44lutidinic acid
CAS:<p>lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.</p>Formula:C7H5NO4Purity:98.06%Color and Shape:White To Off-White Crystalline PowderMolecular weight:167.12RG108
CAS:<p>RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).</p>Formula:C19H14N2O4Purity:98% - 99.43%Color and Shape:SolidMolecular weight:334.33SGC-CBP30
CAS:<p>SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).</p>Formula:C28H33ClN4O3Purity:99.05% - >99.99%Color and Shape:SolidMolecular weight:509.04AZD-1480
CAS:<p>AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.</p>Formula:C14H14ClFN8Purity:98.25% - 99.47%Color and Shape:SolidMolecular weight:348.77JAK-IN-5 hydrochloride
CAS:<p>JAK-IN-5 hydrochloride is a JAK inhibitor [1].</p>Formula:C27H32ClFN6OColor and Shape:SolidMolecular weight:511.03Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Formula:C26H30FN7O3Purity:98.43% - 99.29%Color and Shape:SolidMolecular weight:507.56ARV-825
CAS:<p>ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.</p>Formula:C46H47ClN8O9SPurity:97.15% - 98%Color and Shape:SolidMolecular weight:923.43UNC6934
CAS:<p>UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.</p>Formula:C24H21N5O4Purity:98.67%Color and Shape:SolidMolecular weight:443.45Annaosanchun
CAS:<p>Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).</p>Formula:C19H32O3Purity:99.58%Color and Shape:SolidMolecular weight:308.46GS-829845
CAS:<p>GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life</p>Formula:C17H19N5O2SPurity:99.93%Color and Shape:SolidMolecular weight:357.43CX-6258 hydrochloride
CAS:<p>CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).</p>Formula:C26H24ClN3O3·HClPurity:96.03% - 98.60%Color and Shape:SolidMolecular weight:498.4CBHcy
CAS:<p>CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.</p>Formula:C9H17NO4SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:235.3TNG-462
CAS:<p>TNG-462 is a oral, potent and selective PRMT5 inhibitor for the treatment of MTAP-deficient and/or MTA-accumulating cancers (e.g., pancreatic & bladder).</p>Formula:C28H36N6O2SPurity:98.7%Color and Shape:SolidMolecular weight:520.69MIV-6R
CAS:<p>MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.</p>Formula:C27H35N3OPurity:99.81% - 99.88%Color and Shape:SolidMolecular weight:417.59Talazoparib tosylate
CAS:<p>PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.</p>Formula:C26H22F2N6O4SPurity:99.79%Color and Shape:SolidMolecular weight:552.55Zavondemstat
CAS:<p>Zavondemstat (QC8222 free base) is a KDM4 inhibitor with anticancer and antitumor activity for the study of triple-negative and breast cancers.</p>Formula:C26H29N3O3Purity:99.43% - 99.53%Color and Shape:SolidMolecular weight:431.53MS023 dihydrochloride
CAS:<p>MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.</p>Formula:C17H27Cl2N3OPurity:99.52%Color and Shape:SolidMolecular weight:360.32Cerdulatinib hydrochloride
CAS:<p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.</p>Formula:C20H28ClN7O3SPurity:99.85%Color and Shape:SolidMolecular weight:482Chromium(III) acetate
CAS:<p>Chromium(III) acetate （Chromium acetate） is a small molecule ionic crosslinker that is used as a feedstock for the synthesis of other compounds.</p>Formula:C2H3O2CrPurity:99.9%Color and Shape:Blue-Green Powder Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment It Is Used InMolecular weight:76.37(S)-HH2853
CAS:<p>(S)-HH2853 is a potent EZH1/2 inhibitor, aromatic, <100 nM IC50 for EZH2_Y641F, promising for anti-tumor/autoimmune research.</p>Formula:C31H36F3N7O3Purity:97.18% - 99.74%Color and Shape:SolidMolecular weight:611.66MRK-740
CAS:<p>MRK-740 is a PRDM9 histone methyltransferase inhibitor that inhibits H3K4 methylation.</p>Formula:C25H32N6O3Purity:99.66%Color and Shape:SolidMolecular weight:464.56BI-9321 trihydrochloride
CAS:<p>BI-9321 trihydrochloride (BI9321 trihydrochloride) is an NSD3-PWWP1 antagonist that downregulates Myc messenger RNA expression.</p>Formula:C22H24Cl3FN4Purity:99.12% - 99.34%Color and Shape:SolidMolecular weight:469.81R 59-022
CAS:<p>R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.</p>Formula:C27H26FN3OSPurity:98.55%Color and Shape:SolidMolecular weight:459.58PFI-2
CAS:<p>PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other</p>Formula:C23H25F4N3O3SPurity:99.38%Color and Shape:SolidMolecular weight:499.52NVP-BSK805
CAS:<p>NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.</p>Formula:C27H28F2N6OPurity:98%Color and Shape:SolidMolecular weight:490.55MK-5108
CAS:<p>MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.</p>Formula:C22H21ClFN3O3SPurity:99.22%Color and Shape:SolidMolecular weight:461.94Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44SCH-1473759 hydrochloride
CAS:<p>SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).</p>Formula:C20H27ClN8OSPurity:98.29%Color and Shape:SolidMolecular weight:463GSK2807 Trifluoroacetate
CAS:<p>GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).</p>Formula:C21H33F3N8O7Purity:99.95%Color and Shape:SolidMolecular weight:566.53(R)-Dihydrolipoic acid
CAS:<p>(R)-Dihydrolipoic acid, the biochemically significant R-enantiomer, partakes in biochemical transformations.</p>Formula:C8H16O2S2Purity:98%Color and Shape:SolidMolecular weight:208.33Solrikitug
CAS:<p>Solrikitug,Anti-CRLF2 humanized IgG1κ monoclonal antibody.</p>Purity:95%Color and Shape:LiquidTazemetostat trihydrochloride
CAS:<p>Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.</p>Formula:C34H47Cl3N4O4Purity:98%Color and Shape:SolidMolecular weight:682.12Acedapsone
CAS:<p>Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.</p>Formula:C16H16N2O4SPurity:98%Color and Shape:SolidMolecular weight:332.37Diethyl bipy55'DC
CAS:<p>"Diethyl bipy55'DC blocks CP4H, crucial for collagen stability via hydroxylation in cells."</p>Formula:C16H16N2O4Purity:98%Color and Shape:SolidMolecular weight:300.312-PADQZ
CAS:<p>DPQ is an antiviral compound.</p>Formula:C14H19N5O2Purity:98%Color and Shape:White PowderMolecular weight:289.33Nicotinamide-d4
CAS:<p>Nicotinamide-d4 is a deuterium-labelled compound of nicotinamide for isotope tracing. Nicotinamide, a vitamin B3 derivative, inhibits SIRT1 and SIRT2.</p>Formula:C6H2D4N2OPurity:99.746%Color and Shape:SolidMolecular weight:126.15193 D7
CAS:<p>193 D7 is an inhibitor of histone demethylase JMJD1C (IC50= 0.59 μM in in vitro demethylation assay). In vivo, 193 D7 suppresses tumors by targeting intratumoral Treg cells in mouse tumor models.</p>Formula:C16H15NO4SColor and Shape:SolidMolecular weight:317.36GSK 4027
CAS:<p>GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.</p>Formula:C17H21BrN4OColor and Shape:SolidMolecular weight:377.28I-BET787
CAS:<p>I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.</p>Formula:C16H20ClN3O2Color and Shape:SolidMolecular weight:321.80CrBKA
CAS:<p>CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .</p>Formula:C28H31N3O6Color and Shape:SolidMolecular weight:505.56AdipoR agonist 1
CAS:<p>AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.</p>Formula:C26H35N3O3Color and Shape:SolidMolecular weight:437.57HDAC6-IN-27
CAS:<p>HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].</p>Formula:C15H15N3O4Color and Shape:SolidMolecular weight:301.3BG47
CAS:<p>BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.</p>Formula:C25H22N4O2SColor and Shape:SolidMolecular weight:442.54Guanosine-5'-triphosphate disodium salt
CAS:<p>5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.</p>Formula:C10H14N5Na2O14P3Purity:95.69% - 99.96%Color and Shape:Odorless White SolidMolecular weight:567.14GSK-J1 lithium salt
CAS:<p>GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.</p>Formula:C22H22LiN5O2Purity:98%Color and Shape:SolidMolecular weight:395.38BG14
CAS:<p>BG14: High-res optical epigenetic control; photo-inhibits human histone deacetylases with visible light.</p>Formula:C21H21N5OColor and Shape:SolidMolecular weight:359.433KAT6-IN-1
CAS:<p>KAT6-IN-1 is a potent KAT6 inhibitor. KAT6-IN-1 can be used in research of cancer [1] .</p>Formula:C19H18N4O5SColor and Shape:SolidMolecular weight:414.43ZM39923
CAS:<p>ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM).</p>Formula:C23H25NOPurity:98%Color and Shape:SolidMolecular weight:331.45KR-39038
CAS:<p>KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.</p>Formula:C24H32ClFN6OColor and Shape:SolidMolecular weight:475.00BChE/HDAC6-IN-2
CAS:<p>BChE/HDAC6-IN-2 is an inhibitor of BChE and HDAC6 with neuroprotective and ROS scavenging activity and a metal ion co-agonist and inhibits tau phosphorylation.</p>Formula:C27H30N4O4Purity:98.47%Color and Shape:SoildMolecular weight:474.55BG48
CAS:<p>BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.</p>Formula:C25H23N5OSColor and Shape:SolidMolecular weight:441.55(3S,4S)-Tofacitinib
CAS:<p>(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.</p>Formula:C16H20N6OPurity:98%Color and Shape:SolidMolecular weight:312.37Asteltoxin
CAS:<p>Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.</p>Formula:C23H30O7Color and Shape:SolidMolecular weight:418.486HDAC2-IN-2
CAS:<p>HDAC2-IN-2 (compound 124) acts as an HDAC2 inhibitor, exhibiting a Kd value ranging from 0.1-1 μM.</p>Formula:C18H15N3O3SColor and Shape:SolidMolecular weight:353.40E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46TMPA
CAS:<p>TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.</p>Formula:C21H32O6Purity:99.21%Color and Shape:SolidMolecular weight:380.48GSK-1268997
CAS:<p>GSK-1268997 is a bio-active chemical.</p>Formula:C21H23N7O3SPurity:99.33% - 99.81%Color and Shape:SolidMolecular weight:453.52UNC0224
CAS:<p>UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.</p>Formula:C26H43N7O2Purity:99.80%Color and Shape:SolidMolecular weight:485.67MY-1B
CAS:<p>MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.</p>Formula:C22H18BrN3O2Purity:99.81% - >99.99%Color and Shape:SoildMolecular weight:436.3JAK-IN-30
CAS:<p>JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50</p>Formula:C19H26N8SPurity:98%Color and Shape:SolidMolecular weight:398.53ZYJ-34c
CAS:<p>ZYJ-34c is a potent oral antitumor activities histone deacetylase inhibitor (HDACi).</p>Formula:C31H42N4O7Purity:98%Color and Shape:SolidMolecular weight:582.69SIRT1-IN-3
CAS:<p>SIRT1-IN-3 (compound 3j) is a potent and selective inhibitor of silent information regulator 1 (SIRT1) with an IC 50 of 4.2 μM [1].</p>Formula:C13H15BrN2OColor and Shape:SolidMolecular weight:295.17Eleven-Nineteen-Leukemia Protein IN-1
CAS:<p>ENL-IN-1: Potent ENL YEATS domain inhibitor with 14.5 nM IC50, enhances thermal stability in vitro.</p>Formula:C27H33N7O2Purity:98%Color and Shape:SolidMolecular weight:487.6Angiogenesis agent 1
CAS:<p>Compound C-31, a salidroside-based glycoside, activates HIF-1α and may aid in diabetic limb ischemia studies.</p>Formula:C20H24O7Purity:98%Color and Shape:SolidMolecular weight:376.4LSD1-IN-5
CAS:<p>LSD1-IN-5, a reversible LSD1 inhibitor, boosts H3K4me2 without affecting LSD1 expression; IC50: 121 nM.</p>Formula:C15H13BrN2O3Purity:98%Color and Shape:SolidMolecular weight:349.18EZH2-IN-7
CAS:<p>EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.</p>Formula:C31H37D2N5O3SColor and Shape:SolidMolecular weight:563.75CM-579
CAS:<p>CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.</p>Formula:C29H40N4O3Purity:99.23%Color and Shape:SolidMolecular weight:492.655-Aza-4'-thio-2'-deoxycytidine
CAS:<p>5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].</p>Formula:C8H12N4O3SColor and Shape:SolidMolecular weight:244.27Tripolin A
CAS:<p>Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)</p>Formula:C15H11NO3Purity:98%Color and Shape:SolidMolecular weight:253.25DC_C66
CAS:<p>DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.</p>Formula:C28H22NO2Purity:98%Color and Shape:SolidMolecular weight:404.48Aurora kinase inhibitor-9
CAS:<p>Aurora kinase inhibitor-9 (9d) targets AURKA/B with IC50: 0.093 μM for A and 0.09 μM for B, with wide anti-proliferative effects.</p>Formula:C19H17Cl2N3O4SColor and Shape:SolidMolecular weight:454.33G9a-IN-2
CAS:<p>G9a-IN-2 (Compound 7i) is an inhibitor of the histone methyltransferase G9a, with an IC50 of 0.024 μM. It can reduce the levels of H3K9me2 and induce the expression of γ-globin mRNA. G9a-IN-2 shows potential for improving Sickle Cell Disease (SCD).</p>Formula:C30H42N4O4Color and Shape:SolidMolecular weight:522.68HDAC1/MAO-B-IN-1
CAS:<p>HDAC1/MAO-B-IN-1 is a selective Alzheimer’s research inhibitor with IC50s: HDAC1 (21.4 nM) & MAO-B (99 nM); crosses the blood-brain barrier.</p>Formula:C18H17ClN2O2Color and Shape:SolidMolecular weight:328.79Tankyrase-IN-4
<p>Tankyrase-IN-4 is a potent inhibitor of tankyrase 1 (TNKS1), exhibiting an IC50 of 0.8 nM, and is utilized in cancer research.</p>Formula:C25H24N6O5Color and Shape:SolidMolecular weight:488.5LP99
CAS:<p>LP99 is an epigenetic probe.</p>Formula:C26H30ClN3O4SPurity:99.74%Color and Shape:SolidMolecular weight:516.05TM6089
CAS:<p>TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.</p>Formula:C13H14N4O3SPurity:99.70%Color and Shape:SolidMolecular weight:306.34FAK/aurora kinase-IN-1
CAS:<p>FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].</p>Formula:C23H24ClN7O3Color and Shape:SolidMolecular weight:481.93BET bromodomain inhibitor 3
CAS:<p>BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT.</p>Formula:C18H17N3O4Purity:98%Color and Shape:SolidMolecular weight:339.35PRMT4-IN-1
CAS:<p>PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].</p>Formula:C23H28FN3OPurity:98%Color and Shape:SolidMolecular weight:381.49PARP11 inhibitor ITK7
CAS:<p>ITK7 is a potent, selective PARP11 inhibitor with an IC50 of 14 nM, useful for cellular localization research.</p>Formula:C17H14N4OSColor and Shape:SolidMolecular weight:322.38HDAC-IN-41
CAS:<p>HDAC-IN-41 is a selective class I HDAC inhibiting HDAC1, 2, & 3 with IC50: 0.62-1.46 µM; oral use; has NO-release.</p>Formula:C20H22N4O6SColor and Shape:SolidMolecular weight:446.48BI-831266
CAS:<p>BI-831266 is a potent and selective Aurora kinase B inhibitor.</p>Formula:C27H38ClN7O2Color and Shape:SolidMolecular weight:528.09KF 13218
CAS:<p>KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.</p>Formula:C20H20N2O3Purity:98%Color and Shape:SolidMolecular weight:336.38YUKA1
CAS:<p>YUKA1, a cell-permeable KDM5A inhibitor with a weak effect on KDM5C, increase H3K4me3 and inhibit the proliferation, prevent drug-resistant.</p>Formula:C13H16N4O2SPurity:99.85%Color and Shape:SolidMolecular weight:292.36HDAC-IN-30
CAS:<p>HDAC-IN-30 is a potent HDAC inhibitor targeting HDAC1, 2, 3, 6, and 8 with strong antitumor efficacy.</p>Formula:C22H23N5O3Color and Shape:SolidMolecular weight:405.45HDAC6-IN-14
<p>HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1,</p>Formula:C24H30FN3O4Color and Shape:SolidMolecular weight:443.51JFD00244
CAS:<p>JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.</p>Formula:C30H26N2O4Purity:98%Color and Shape:SolidMolecular weight:478.54Y06036
CAS:<p>Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).</p>Formula:C16H15BrN2O5SPurity:99.97%Color and Shape:SolidMolecular weight:427.27PRMT5-IN-2
CAS:<p>PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.</p>Formula:C17H16ClFN4O4Purity:98%Color and Shape:SolidMolecular weight:394.78NCD38
CAS:<p>NCD38 is a potent, selective LSD1 inhibitor.</p>Formula:C37H37ClF3N3O4Purity:98.21% - 98.86%Color and Shape:SolidMolecular weight:680.16(Rac)-BAY1238097
CAS:<p>(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.</p>Formula:C25H33N5O3Purity:98%Color and Shape:SolidMolecular weight:451.56JAK-2/3-IN-2
CAS:<p>JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 & JAK3 inhibitor with IC50s of 23.85 nM (JAK2) & 18.9 nM (JAK3).</p>Formula:C19H19ClN2OSColor and Shape:SolidMolecular weight:358.89EZM 2302
CAS:<p>EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).Cost-effective and quality-assured.</p>Formula:C29H37ClN6O5Purity:97.47% - ≥98%Color and Shape:SolidMolecular weight:585.09HDAC6-IN-11
CAS:<p>HDAC6-IN-11 (Compound 9) is a cancer cell growth blocker, selectively inhibiting HDAC6 (>300-fold) with an IC50 of 20.7 nM.</p>Formula:C19H16N2O4Color and Shape:SolidMolecular weight:336.34HDAC8/BRPF1-IN-1
CAS:<p>Compound 23a, dual HDAC8/BRPF1 inhibitor: IC50 HDAC8 = 443 nM, Kd BRPF1 = 67 nM; weak against HDAC1/6.</p>Formula:C19H19N3O6SColor and Shape:SolidMolecular weight:417.44OHM1
CAS:<p>OHM1, an analog of HIF1α CTAD, effectively inhibits the interaction between HIF1α CTAD and p300/CBP by targeting the CH1 domain with a binding affinity of 0.53</p>Formula:C24H42N6O5Color and Shape:SolidMolecular weight:494.63J1038
CAS:<p>J1038 is a novel Histone Deacetylase 8 (HDAC8) Inhibitor .</p>Formula:C10H10N2O3SColor and Shape:SolidMolecular weight:238.26A2B57
CAS:<p>A2B57 is a selective SIRT2 inhibitor.</p>Formula:C22H19N5OPurity:98%Color and Shape:SolidMolecular weight:369.42BRD4-BD1-IN-1
CAS:<p>BRD4-BD1-IN-1 (Compound 9a) is a BRD4-BD1 inhibitor(IC50= 38.20 μM).</p>Formula:C16H15BrN4O4Color and Shape:SolidMolecular weight:407.22A2AAR/HDAC-IN-1
CAS:<p>A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.</p>Formula:C24H21N7O2Color and Shape:SolidMolecular weight:439.47ARTD10/PARP10-IN-2
CAS:<p>ARTD10/PARP10-IN-2: A potent, non-selective PARP inhibitor, IC50: ARTD10/PARP10 (2.0μM), ARTD1/PARP1 (9.7μM).</p>Formula:C12H13N3O3Color and Shape:SolidMolecular weight:247.25BNS
CAS:<p>BNS is a potent, prolyl-hydroxylase 2 (PHD2)-selective inhibitor.</p>Formula:C18H16N2O6S2Purity:98%Color and Shape:SolidMolecular weight:420.46MARK-IN-4
CAS:<p>MARK-IN-4 inhibits microtubule kinase (MARK) effectively (IC50: 1 nM), a target for Alzheimer's therapy.</p>Formula:C21H23N7OSColor and Shape:SolidMolecular weight:421.52DCE_42
CAS:<p>DCE_42 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.</p>Formula:C22H19N9O2SPurity:98%Color and Shape:SolidMolecular weight:473.51JAK-IN-11
CAS:<p>JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.</p>Formula:C23H22FN5O4SPurity:99.75%Color and Shape:SolidMolecular weight:483.52PARP1-IN-9
CAS:<p>PARP1-IN-9, potent PARP1 inhibitor with 30.51 nM IC50, outperforms Olaparib in anticancer efficacy.</p>Formula:C18H21N3O5Color and Shape:SolidMolecular weight:359.38BRD4 Inhibitor-25
<p>BRD4 Inhibitor-25 blocks BRD4 (BD1: IC50 0.82 μM, BD2: 1.94 μM), induces cell death in ovarian cancer, used in cancer research.</p>Formula:C29H27N5O6SColor and Shape:SolidMolecular weight:573.62CAY10685
CAS:<p>CAY10685, a CPTH2 analog with an alkyne for click reactions, inhibits NAT10 to study cancer-related chromatin changes.</p>Formula:C17H16ClN3SColor and Shape:SolidMolecular weight:329.85DNMT3A-IN-1
CAS:<p>DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).</p>Formula:C30H38N6O4Color and Shape:SolidMolecular weight:546.66NCDM-32B
CAS:<p>NCDM-32B, a novel potent and selective KDM4 inhibitor, impairs viability and transforms phenotypes of basal breast cancer.</p>Formula:C15H30N2O4Purity:98%Color and Shape:SolidMolecular weight:302.41AChE/HDAC-IN-1
CAS:<p>COX-2-IN-23 (A10) inhibits AChE & HDAC (IC50s: 0.12 & 0.23 nM), has antioxidant/metal-binding traits, and is used in Alzheimer's research.</p>Formula:C26H27ClN4O3Color and Shape:SolidMolecular weight:478.97TYK2-IN-11
CAS:<p>TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.</p>Formula:C18H17N5O3SColor and Shape:SolidMolecular weight:383.42SGC6870
CAS:<p>SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.</p>Formula:C23H21BrN2O2SColor and Shape:SolidMolecular weight:469.39BRD4 Inhibitor-26
<p>BRD4 Inhibitor-26: blocks BRD4 (BD1 and BD2) with IC50 of 0.82 μM & 1.94 μM; used in ovarian cancer research.</p>Formula:C29H27N5O6SColor and Shape:SolidMolecular weight:573.62103D5R
CAS:<p>103D5R selectively inhibits hif-1α, reducing its levels in hypoxia or with cobalt ions, dose- and time-dependently.</p>Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4MAT2A-IN-6
CAS:<p>MAT2A-IN-6 inhibits MAT2A, may slow MTAP-deficient cancer cell growth, has research value in cancer.</p>Formula:C18H13ClF3N3O3Color and Shape:SolidMolecular weight:411.76CP-690550A
CAS:<p>Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.</p>Formula:C15H21N5O2Color and Shape:SolidMolecular weight:303.36MZ-242
CAS:<p>MZ-242 is an effective and selective inhibitor of Sirt2.</p>Formula:C24H27N7O3S2Purity:98%Color and Shape:SolidMolecular weight:525.65Antiproliferative agent-17
CAS:<p>Antiproliferative Agent-17 exhibits both antimicrobial properties against Gram-positive bacteria and anticancer activity [1].</p>Formula:C26H28N2OSColor and Shape:SolidMolecular weight:416.58KDOAM-25
CAS:<p>KDOAM-25, a potent KDM5 inhibitor, enhances H3K4 methylation, hampers MM1S cell growth; IC50: 71 nM (5A), 19 nM (5B), 69 nM (5C/D).</p>Formula:C15H25N5O2Purity:98%Color and Shape:SolidMolecular weight:307.39HDAC6/8/BRPF1-IN-1
CAS:<p>HDAC6/8/BRPF1-IN-1 is a cancer-research inhibitor for HDAC6, HDAC8, BRPF1 with IC50: 344-908 nM and Kd: 175.2 nM.</p>Formula:C18H17N3O5SColor and Shape:SolidMolecular weight:387.41UNC2327
CAS:<p>UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).</p>Formula:C14H17N5O2SPurity:98%Color and Shape:SolidMolecular weight:319.38AA-CW236
CAS:<p>AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).</p>Formula:C17H16ClF3N4O2Color and Shape:SolidMolecular weight:400.78NN-390
CAS:<p>NN-390: selective HDAC6 inhibitor, IC50 9.8 μM, blood-brain barrier penetrant, potential for metastatic group 3 neural tube cancer research.</p>Formula:C17H16F4N2O4SColor and Shape:SolidMolecular weight:420.38EZH2-IN-9
CAS:<p>EZH2-IN-9 inhibits EZH2, targeting SET mutations linked to cancer by reducing H3K27me3 levels.</p>Formula:C28H32ClF2N3O5SColor and Shape:SolidMolecular weight:596.09EZH2-IN-11
CAS:<p>EZH2-IN-11, a potent E2HZ inhibitor with potential for cancer treatment, is highlighted in patent WO2019204490A1.</p>Formula:C28H36ClN3O5SColor and Shape:SolidMolecular weight:562.12Aurora Kinases-IN-2
CAS:<p>Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.</p>Formula:C22H18ClN5O3Color and Shape:SolidMolecular weight:435.86DC-BPi-11
CAS:<p>DC-BPi-11 inhibits BPTF at IC50 698 nM and significantly reduces leukemia cell growth.</p>Formula:C20H23N5O2SColor and Shape:SolidMolecular weight:397.49JS1310
CAS:<p>JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.</p>Formula:C23H22FN5O3Color and Shape:SolidMolecular weight:435.45CypD inhibitor C-9
CAS:<p>CypD inhibitor C-9 is a CypD inhibitor, it attenuates mitochondrial and cellular perturbation insulted by Aß and calcium stress.</p>Formula:C22H22N4O4S2Color and Shape:SolidMolecular weight:470.56BET-IN-2
CAS:<p>BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).</p>Formula:C23H29N3OPurity:98%Color and Shape:SolidMolecular weight:363.5PIM1-IN-6
CAS:<p>PIM1-IN-6 (5h) inhibits PIM-1 (IC50: 0.60 μM) and is cytotoxic to HCT-116 (IC50: 1.51 μM) and MCF-7 cells (IC50: 15.2 μM).</p>Formula:C21H18N6O4Color and Shape:SolidMolecular weight:418.41TNKS-IN-41
CAS:<p>TNKS-IN-41 highly potent and selective inhibitor of tankyrase.</p>Formula:C24H22N10O2Purity:98%Color and Shape:SolidMolecular weight:482.5K00135
CAS:<p>K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics.</p>Formula:C18H18N4OPurity:98.16%Color and Shape:SolidMolecular weight:306.36MC-1353
CAS:<p>MC-1353 is a potent, selective inhibitor of HDAC class I.</p>Formula:C16H16N2O3Color and Shape:SolidMolecular weight:284.31PBRM1-BD2-IN-1
CAS:<p>PBRM1-BD2-IN-1: Selective PBRM1 inhibitor with Kd 0.7μM, IC50 0.2μM, useful in cancer research.</p>Formula:C17H19ClN2OColor and Shape:SolidMolecular weight:302.84-iodo-SAHA
CAS:<p>4-Iodo-SAHA (1k), an oral HDAC inhibitor for cancer research, has EC50s from 0.12 to 1.3 μM across various cell lines.</p>Formula:C14H19IN2O3Color and Shape:SolidMolecular weight:390.22HDAC1-IN-4
CAS:<p>HDAC1-IN-4 is a potent inhibitor of Plasmodium falciparum HDAC1 (PfHDAC1) with low cytotoxicity and antimalarial effects (IC50<5 nM).</p>Formula:C21H24BrClN6O2Color and Shape:SolidMolecular weight:507.82JAK-IN-20
CAS:<p>JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.</p>Formula:C28H30FN7O2Color and Shape:SolidMolecular weight:515.58PIM1-IN-7
CAS:<p>PIM1-IN-7 inhibits PIM-1 (IC50: 0.67μM), toxic to HCT-116/MCF-7 cells (IC50: 42.9/7.68μM).</p>Formula:C23H23N5OColor and Shape:SolidMolecular weight:385.46HDAC/CK2-IN-1
CAS:<p>HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.</p>Formula:C15H18Br4N4O2Color and Shape:SolidMolecular weight:605.95BRD4-BD1/2-IN-1
CAS:<p>BRD4-BD1/2-IN-1 efficiently blocks BRD4 BD-1/2 under 100 nM IC50 (US20150148375A1, cmpd 5).</p>Formula:C21H14F2N4O2Color and Shape:SolidMolecular weight:392.36DPQ
CAS:<p>DPQ inhibits PARP-1, aids in neuroprotection, restores ATP, and lessens neuronal injury from NMDA.</p>Formula:C18H26N2O2Purity:98%Color and Shape:SolidMolecular weight:302.41AMPK activator 9
CAS:<p>AMPK activator 9 (ZM-6) is a potent α2β1γ1 agonist with an EC50 of 1.1 µM, potential for type 2 diabetes research.</p>Formula:C31H28F4N4O4Color and Shape:SolidMolecular weight:596.57ART-IN-1
CAS:<p>ART-IN-1 (compound 7) is a selective inhibitor of PARP with IC 50 s of 19, 22, 2.4, >100, 1.1 μM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively [1].</p>Formula:C14H13NO2SColor and Shape:SolidMolecular weight:259.32Peficitinib hydrochloride
CAS:<p>Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).</p>Formula:C18H23ClN4O2Color and Shape:SolidMolecular weight:362.86VE-465
CAS:<p>VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.</p>Formula:C22H28N8OSColor and Shape:SolidMolecular weight:452.58PRMT5-IN-17
CAS:<p>PRMT5-IN-17 is a PRMT5-blocking compound with anticancer properties, linked to epigenetic changes.</p>Formula:C26H33N7O2Color and Shape:SolidMolecular weight:475.59HDAC/NAMPT-IN-1
CAS:<p>HDAC/NAMPT-IN-1 (compound 39h) simultaneously inhibits HDAC and NAMPT, exhibiting IC 50 values ranging from 0.72 to 37081 nM for HDAC and 1618 nM for NAMPT [1].</p>Formula:C19H21N5O2Color and Shape:SolidMolecular weight:351.4IACS-9571 hydrochloride
CAS:<p>IACS-9571 hydrochloride: potent TRIM24/BRPF1 inhibitor; IC50 = 8 nM (TRIM24); Kd = 31 nM (TRIM24), 14 nM (BRPF1).</p>Formula:C32H43ClN4O8SColor and Shape:SolidMolecular weight:679.22KDM2B-IN-4
CAS:<p>KDM2B-IN-4, from patent WO2016112284A1 as 182b, is a potent KDM2B inhibitor used in cancer research.</p>Formula:C24H28N2O2Color and Shape:SolidMolecular weight:376.49CEP-8983
CAS:<p>CEP-8983 is a PARP inhibitor potentially for the treatment of solid tumours.</p>Formula:C18H14N2O3Purity:98%Color and Shape:SolidMolecular weight:306.32BRM/BRG1 ATP Inhibitor-4
CAS:<p>BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders.</p>Formula:C25H32N6O3SColor and Shape:SolidMolecular weight:496.62MAT2A-IN-7
CAS:<p>MAT2A-IN-7 inhibits MAT2A in various cancers, especially MTAP-deficient cancer cells, with potential for research use.</p>Formula:C17H13ClF3N3O2Color and Shape:SolidMolecular weight:383.75Dihydro-5-azacytidine acetate
CAS:<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Formula:C10H18N4O7Purity:98%Color and Shape:SolidMolecular weight:306.27LT052
CAS:<p>LT052 is a BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 signaling inflammatory pathway.</p>Formula:C22H19N5O4SPurity:98.82%Color and Shape:SolidMolecular weight:449.48Sirt2-IN-6
CAS:<p>Sirt2-IN-6 is a potent and selective inhibitor of SIRT2 (IC50: 0.815 μM) and can be used to study cancer.</p>Formula:C26H26N6O3SColor and Shape:SolidMolecular weight:502.59BRD4884
CAS:<p>BRD4884 is a highly selective and efficient HDAC1 and HDAC2 inhibitor that also inhibits HDAC3, used in research on neurological disorders.</p>Formula:C18H19FN2O2Purity:99.19% - 99.21%Color and Shape:SolidMolecular weight:314.35Lorpucitinib
CAS:<p>Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.</p>Formula:C22H28N6O2Purity:99.72%Color and Shape:SolidMolecular weight:408.5KDM2/7-IN-1
CAS:<p>KDM2/7-IN-1 is a selective histone demethylase inhibitor (IC50s: 0.2–>120 μM) that inhibits HeLa and KYSE-150 cell proliferation, epigenetic and cancer.</p>Formula:C15H27NO4Purity:99.87%Color and Shape:SolidMolecular weight:285.38BETi-211
CAS:<p>BETi-211 is a selective inhibitor BET bromodomain.</p>Formula:C26H29N7O3Color and Shape:SolidMolecular weight:487.55ZYJ-25e
CAS:<p>ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.</p>Formula:C30H40N4O8Purity:98%Color and Shape:SolidMolecular weight:584.66IND 1316
CAS:<p>IND 1316 is an activator of AMP-activated protein kinase (AMPK).</p>Formula:C22H17NO3Color and Shape:SolidMolecular weight:343.38CCT077791
CAS:<p>CCT077791 is a potent inhibitor of p300 and PCAF histone acetyltransferase activity for cancer research.</p>Formula:C9H5ClN2O3SPurity:98.60%Color and Shape:SolidMolecular weight:256.67ZIKV-IN-2
CAS:<p>ZIKV-IN-2 blocks ZIKV replication, is a strong NS5 MTase inhibitor (IC50: 38.86 μM), and aids Zika virus research.</p>Formula:C39H42O4Color and Shape:SolidMolecular weight:574.75KU-0058684
CAS:<p>KU-0058684 is a potent PARP and DNA-PK inhibitors.</p>Formula:C19H14FN3O3Color and Shape:SolidMolecular weight:351.33ML753286
CAS:<p>ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.</p>Formula:C20H25N3O3Purity:98%Color and Shape:SolidMolecular weight:355.43Trotabresib
CAS:<p>Trotabresib (CC-90010) is an orally active inhibitor of BET and can be used in studies about advanced solid tumors.</p>Formula:C21H21NO4SPurity:99.86%Color and Shape:SolidMolecular weight:383.46JAK1-IN-4
CAS:<p>JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).</p>Formula:C26H32FN9O2Purity:98%Color and Shape:SolidMolecular weight:521.59Y02224
CAS:<p>Y02224 is a BET inhibitor. It shows the reasonable antiproliferative effect on leukemia cells.</p>Formula:C20H17BrN2O4SPurity:98%Color and Shape:SolidMolecular weight:461.33Dot1L-IN-5
CAS:<p>Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein ( DOT1L ) with an IC 50 SPA DOT1L of 0.17 nM [1].</p>Formula:C23H19ClF2N8O5SColor and Shape:SolidMolecular weight:592.96HAT-IN-1
CAS:<p>HAT-IN-1 is an inhibitor of HAT used in the research of cancer.</p>Formula:C23H18BrF4N3O4Purity:98%Color and Shape:SolidMolecular weight:556.3Helenalin Acetate
CAS:<p>Helenalin Acetate: anti-inflammatory, anti-cancer, hinders C/EBPß and p300 cooperation.</p>Formula:C17H20O5Purity:98%Color and Shape:SolidMolecular weight:304.34HDAC-IN-45
CAS:<p>HDAC-IN-45, a small HDAC blocker, forms H-bonds with Y303 and shows anticancer properties; IC50 for HDAC1/2/3: 0.108/0.585/0.563 μM.</p>Formula:C25H20ClFN8OColor and Shape:SolidMolecular weight:502.93DM-01
CAS:<p>DM-01 is a potent and selective inhibitor of EZH2.</p>Formula:C23H24F3N3O2Color and Shape:SolidMolecular weight:431.45dBRD9-A
CAS:<p>Potent BRD9 degrader that binds selectively, fully degrades BRD9 at low doses, and hinders synovial sarcoma growth in vitro and in mice.</p>Formula:C42H49N7O8Color and Shape:SolidMolecular weight:779.88PB118
<p>PB118 clears Aβ, boosts phagocytosis, enhances tubulin networks, reduces p-tau & inflammation in AD; HDAC6 IC50: 5.6 nM.</p>Formula:C18H19FN2O2Color and Shape:SoildMolecular weight:314.35Dot1L-IN-7
CAS:<p>Dot1L-IN-7 (compound 25), a potent DOT1L inhibitor with an IC50 of 1.0 μM, selectively kills MLL-AF9, sparing E2A-HLF cells.</p>Formula:C23H27N9O2Color and Shape:SolidMolecular weight:461.52CeMMEC2
CAS:<p>CeMMEC2, a novel inhibitor of BRD4, binds both the first and the second bromodomain of BRD4.</p>Formula:C14H19N5Color and Shape:SolidMolecular weight:257.33(1S,2R)-Tranylcypromine hydrochloride
CAS:<p>(1S,2R)-Tranylcypromine hydrochloride ((1S,2R)-SKF 385), a potent antidepressant, functions by inhibiting both MAO and LSD1.</p>Formula:C9H12ClNColor and Shape:SolidMolecular weight:169.651Guadecitabine sodium
CAS:<p>Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .</p>Formula:C18H24N9NaO10PPurity:98%Color and Shape:SolidMolecular weight:580.407HDAC6-IN-46
CAS:<p>HDAC6-IN-46 (compound 12) is a selective inhibitor of histone deacetylase 6 (HDAC6), exhibiting an IC50 of 6.2 nM. It is utilized in research related to Alzheimer's disease.</p>Formula:C26H21N3O4Color and Shape:SolidMolecular weight:439.46HDAC3-IN-T326
CAS:<p>HDAC3-IN-T326: potent, selective HDAC3 inhibitor, boosts NF-κB acetylation, activates latent HIV gene expression.</p>Formula:C21H18N6O3SPurity:98%Color and Shape:SolidMolecular weight:434.47Gue1654
CAS:<p>Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.</p>Formula:C23H17N3OS3Purity:98.02% - 98.04%Color and Shape:SolidMolecular weight:447.6LSD1-IN-6
CAS:<p>LSD1-IN-6, a potent LSD1 inhibitor (IC50: 123 nM), enhances H3K4me2 without altering LSD1 expression. Reversible.</p>Formula:C15H13BrN2O3Purity:98%Color and Shape:SolidMolecular weight:349.18SC-9
CAS:<p>SC-9 is a protein kinase C activator.</p>Formula:C22H24ClNO2SPurity:98%Color and Shape:SolidMolecular weight:401.95PS432
CAS:<p>PS432 inhibits atypical PKCs, targets PIF-pocket, reduces tumors in mice sans side effects.</p>Formula:C25H19ClN2O5SPurity:98%Color and Shape:SolidMolecular weight:494.95SMYD2-IN-1
CAS:<p>SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).</p>Formula:C25H25Cl2F2N7O2Purity:98%Color and Shape:SolidMolecular weight:564.41Piribedil dihydrochloride
CAS:<p>dopamine agonist</p>Formula:C16H20Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:371.26Akt Inhibitor X
CAS:<p>Akt Inhibitor X is a cell-permeable and reversible inhibitor of Akt phosphorylation.</p>Formula:C20H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:344.88KDM5B-IN-3
CAS:<p>KDM5B-IN-3 inhibits KDM5B/JARID1B with IC50 of 9.32 μM, useful in gastric cancer studies.</p>Formula:C19H25ClN4O2Color and Shape:SolidMolecular weight:376.88DDP-38003 dihydrochloride
CAS:<p>DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).</p>Formula:C21H28Cl2N4OPurity:99.76%Color and Shape:SolidMolecular weight:423.38CID-4785700
CAS:<p>CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75</p>Formula:C22H23ClFN3O3Purity:98.16%Color and Shape:SolidMolecular weight:431.89Kgp-IN-1
CAS:<p>Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.</p>Formula:C19H24F4N4O3Purity:98%Color and Shape:SolidMolecular weight:432.41PARP-1/2-IN-1
CAS:<p>PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).</p>Formula:C24H27FN4O3Color and Shape:SolidMolecular weight:438.49NSC-636819
CAS:<p>NSC-636819 is a novel inhibitor of KDM4A/KDM4B.</p>Formula:C22H12Cl4N2O4Purity:98%Color and Shape:SolidMolecular weight:510.15M-110
CAS:<p>M-110 selectively targets PIM kinases, best at PIM-3 (IC50=47nM), and inhibits prostate cancer cell growth (IC50=0.6-0.9μM).</p>Formula:C22H28ClN5O3Purity:99.55%Color and Shape:SolidMolecular weight:445.94MI-1
CAS:<p>MI-1 inhibits Menin-MLL interaction with an IC 50 of 1.9 μM [1].</p>Formula:C19H25N5S2Color and Shape:SolidMolecular weight:387.57
