Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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Dimethyl-bisphenol A
CAS:<p>DMBPA inhibits HIF-1α, promotes its degradation by detaching Hsp90, and reduces Vegfa mRNA expression.</p>Formula:C17H20O2Color and Shape:SolidMolecular weight:256.34TyK2-IN-2
CAS:<p>TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).</p>Formula:C16H18N6OPurity:98%Color and Shape:SolidMolecular weight:310.35SRI-42127
CAS:<p>SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR that inhibits tumor growth and reduces neuropathic pain following nerve injury.</p>Formula:C19H20N6OPurity:99.66%Color and Shape:SolidMolecular weight:348.4SIRT5 inhibitor 6
CAS:<p>SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.</p>Formula:C21H28N6O4SPurity:99.84%Color and Shape:SolidMolecular weight:460.55CTX-0124143
CAS:<p>CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.</p>Formula:C17H13FN2O3SPurity:99.16%Color and Shape:SolidMolecular weight:344.36NSD3-IN-2
CAS:<p>NSD3-IN-2: Potent NSD3 inhibitor, IC50 17.97μM, halts NSCLC growth (H460, H1299, H1650) with anticancer effects.</p>Formula:C17H15N5OSColor and Shape:SolidMolecular weight:337.4NSD3-IN-3
CAS:<p>"NSD3-IN-3, a potent anticancer agent, inhibits NSD3 (IC50: 1.86 μM) and hampers H460 lung cancer cell growth."</p>Formula:C15H17N5O2SColor and Shape:SolidMolecular weight:331.39PRMT5-IN-C17
CAS:<p>PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.</p>Formula:C18H17N3O4SColor and Shape:SolidMolecular weight:371.415WKS
CAS:<p>5WKS, or ZINC97756584, is a G9a inhibitor targeting H3K9me2 for gene silencing research in autoimmune diseases and tumors.</p>Formula:C24H36ClN5O2Purity:98%Color and Shape:SolidMolecular weight:462.03NC-III-49-1
CAS:<p>NC-III-49-1: potent BET inhibitor, binds BRD4/BRDT, inhibits cell growth, reduces c-Myc expression.</p>Formula:C44H50N4O11S2Color and Shape:SoildMolecular weight:875.02CL67
CAS:<p>CL67 is a hypoxia-inducible factor pathway inhibitor. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro.</p>Formula:C38H42N10O2Color and Shape:SolidMolecular weight:670.81HDAC-IN-44
CAS:<p>HDAC-IN-44 is an HDAC inhibitor (IC50: 61.2 nM) with strong anti-cancer effects.</p>Formula:C26H27BrN4O4Color and Shape:SolidMolecular weight:539.42PDAT
CAS:<p>PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.</p>Formula:C15H23N3Purity:98%Color and Shape:SolidMolecular weight:245.36TM6008
CAS:<p>TM6008 is an inhibitor of prolyl hydroxylase that protects against cell death after hypoxia.</p>Formula:C21H17N5O3Purity:98%Color and Shape:SolidMolecular weight:387.39BET bromodomain inhibitor 2
CAS:<p>BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).</p>Formula:C23H30N2O5SColor and Shape:SolidMolecular weight:446.56SKF 91488 dihydrochloride
CAS:<p>histamine N-methyltransferase inhibitor</p>Formula:C7H19Cl2N3SPurity:98%Color and Shape:SolidMolecular weight:248.22GDC-4379
CAS:<p>GDC-4379 is a JAK1 inhibitor that can be used to study asthma.</p>Formula:C21H18ClF2N7O3Color and Shape:SolidMolecular weight:489.86Y08175
CAS:<p>Y08175, a CBP Bromodomain inhibitor, IC50: 37 nM (AlphaScreen), 178.15 nM (HTRF). Useful in prostate cancer research.</p>Formula:C23H19FN4O5Color and Shape:SolidMolecular weight:450.42RSC-133
CAS:<p>promotes the reprogramming of human somatic cells to pluripotent stem cells</p>Formula:C18H15N3O2Purity:98%Color and Shape:SolidMolecular weight:305.33HDAC6-IN-10
CAS:<p>HDAC6-IN-10 is a potent HDAC6 inhibitor with 0.73 nM IC50, highly selective, and hinders multiple myeloma cell growth.</p>Formula:C21H20N4O4Color and Shape:SolidMolecular weight:392.41MAT2A inhibitor 3
CAS:<p>MAT2A inhibitor 3 can be used in the cancer research.</p>Formula:C16H14ClN3OColor and Shape:SolidMolecular weight:299.75MAT2A-IN-5
CAS:<p>MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.</p>Formula:C17H12ClF3N2OColor and Shape:SolidMolecular weight:352.74SIRT6-IN-1
CAS:<p>SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.</p>Formula:C19H14N4O5SColor and Shape:SolidMolecular weight:410.4JAK3i
CAS:<p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>Formula:C18H15FN4O3Purity:98.61% - 99.81%Color and Shape:SolidMolecular weight:354.34ABT-472
CAS:<p>ABT-472 is a novel PARP inhibitor</p>Formula:C20H28N4O5Color and Shape:SolidMolecular weight:404.46INCB054329 Racemate
CAS:<p>INCB054329 Racemate is an inhibitor of BET protein.</p>Formula:C19H16N4O3Purity:98%Color and Shape:SolidMolecular weight:348.36EML741
CAS:<p>EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b.</p>Formula:C31H49N5O2Purity:98%Color and Shape:SolidMolecular weight:523.75IHCH-3064
CAS:<p>IHCH-3064: dual-action cancer immunotherapy, A2AR affinity (Ki 2.2 nM), selective HDAC1 inhibitor (IC50 80.2 nM).</p>Formula:C25H21N9O2Color and Shape:SolidMolecular weight:479.49HDAC6-IN-6
CAS:<p>HDAC6-IN-6: Potent HDAC6 blocker, BBB-permeable, IC50: 0.025μM; inhibits AChE, Aβ 1-42 aggregation; promotes neurite growth, low neurotoxicity.</p>Formula:C20H15N3O2Color and Shape:SolidMolecular weight:329.35A2AAR/HDAC-IN-2
CAS:<p>A2AAR/HDAC-IN-2: potent dual A2AAR/HDAC inhib., Ki 10.3 nM, IC50 18.5 nM, anti-tumor potential.</p>Formula:C23H26N6O4Color and Shape:SolidMolecular weight:450.49NSC 698600
CAS:<p>NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].</p>Formula:C14H12N2O2SColor and Shape:SolidMolecular weight:272.32SPC-180002
CAS:<p>SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.</p>Formula:C18H23NO4Purity:98%Color and Shape:SolidMolecular weight:317.38JAK-IN-18
CAS:<p>"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."</p>Formula:C27H28F2N6O3Color and Shape:SolidMolecular weight:522.55Setin-1
CAS:<p>Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.</p>Formula:C29H21F3N2O2Purity:98%Color and Shape:SolidMolecular weight:486.48GSK 525768A
CAS:<p>GSK 525768A, the inactive enantiomer of GSK525762A, exhibits no activity towards BET.</p>Formula:C22H22ClN5O2Color and Shape:SolidMolecular weight:423.9OXFBD03
CAS:<p>OXFBD03 is the bromodomain and extra terminal domain bromodomain family member BRD4(1) inhibitor.</p>Formula:C20H19NO4Purity:98%Color and Shape:SolidMolecular weight:337.37LY 170198
CAS:<p>LY 170198 is a protein kinase C inhibitor.</p>Formula:C22H25N5O5Purity:98%Color and Shape:SolidMolecular weight:439.46HPCG
CAS:<p>HPCG is an inhibitor of HIF-1α prolyl hydroxylase.</p>Formula:C8H8N2O4Color and Shape:SolidMolecular weight:196.16DHPCC-9
CAS:<p>DHPCC-9 is an inhibitor of Pim kinase.</p>Formula:C15H10N2OColor and Shape:SolidMolecular weight:234.25DC_501
CAS:<p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>Formula:C25H23Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:452.38Sirtuin modulator 4
CAS:<p>Sirtuin modulator 4 inhibits SIRT1 (EC50: 51-100 μM), may extend cell life and prevent diseases like diabetes and cancer.</p>Formula:C18H10N2O2SColor and Shape:SolidMolecular weight:318.35DCE_254
CAS:<p>DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.</p>Formula:C21H17N9OSPurity:98%Color and Shape:SolidMolecular weight:443.48Langkamide
CAS:<p>Langkamide is a HIF-2 inhibitor with EC₅₀ values of 14.0 uM.</p>Formula:C16H17NO5Purity:98%Color and Shape:SolidMolecular weight:303.31I-BET151 dihydrochloride
CAS:<p>I-BET 151 dihydrochloride is a BET bromodomain inhibitor that prevents BET from recruiting to chromatin.</p>Formula:C23H23Cl2N5O3Purity:98%Color and Shape:SolidMolecular weight:488.37Vibsanin A
CAS:<p>Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.</p>Formula:C25H38O4Color and Shape:SolidMolecular weight:402.57BF1
CAS:<p>BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.</p>Formula:C12H12ClN3SColor and Shape:SolidMolecular weight:265.76Farnesylthiotriazole
CAS:<p>Farnesylthiotriazole is a persistent PKC activator agent.</p>Formula:C17H27N3SPurity:98%Color and Shape:SolidMolecular weight:305.48Tenovin-D3
CAS:<p>Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.</p>Formula:C22H27Cl3N4O3SPurity:98%Color and Shape:SolidMolecular weight:533.9ML399
CAS:<p>ML399 inhibits menin-MLL interaction, targeting MLL leukemia cells with selective, potent action.</p>Formula:C27H28FN3O2Purity:98%Color and Shape:SolidMolecular weight:445.53iBRD4-BD1
CAS:<p>iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.</p>Formula:C29H30F3N5OColor and Shape:SolidMolecular weight:521.58
