Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2607 products of "Chromatin/Epigenetics"
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GW843682X
CAS:GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Formula:C22H18F3N3O4SPurity:99.92%Color and Shape:SolidMolecular weight:477.46Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formula:C28H40O8Purity:99.32% - 99.37%Color and Shape:SolidMolecular weight:504.61Ref: TM-T16526
1mg58.00€5mg160.00€10mg268.00€25mg530.00€50mg827.00€100mg1,314.00€200mg1,773.00€1mL*10mM (DMSO)170.00€TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purity:99.73%Color and Shape:SolidMolecular weight:547.96Ref: TM-T6039
1mg38.00€5mg80.00€10mg120.00€25mg216.00€50mg354.00€100mg512.00€200mg727.00€1mL*10mM (DMSO)96.00€DC-CPin7
CAS:DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].Formula:C19H22N2O5Color and Shape:SolidMolecular weight:358.39OICR-0547
CAS:OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.Formula:C28H29F3N4O4Purity:98%Color and Shape:SolidMolecular weight:542.55HIF-1α inhibitor-1
CAS:HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor.Formula:C15H11N3O4Color and Shape:SolidMolecular weight:297.27JAK-IN-10
CAS:JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.Formula:C20H18FN5O3SPurity:99.53%Color and Shape:SolidMolecular weight:427.45Ref: TM-T13571
1mg82.00€5mg167.00€10mg246.00€25mg405.00€50mg572.00€100mg772.00€500mg1,539.00€1mL*10mM (DMSO)178.00€NSC-311068
CAS:NSC-311068: A selective TET1 inhibitor, reducing 5hmC and AML cell viability with high TET1.Formula:C10H6N4O4SColor and Shape:SolidMolecular weight:278.24HDAC6-IN-11
CAS:HDAC6-IN-11 (Compound 9) is a cancer cell growth blocker, selectively inhibiting HDAC6 (>300-fold) with an IC50 of 20.7 nM.Formula:C19H16N2O4Color and Shape:SolidMolecular weight:336.34Bisindolylmaleimide II
CAS:protein kinase C (PKC) inhibitorFormula:C27H26N4O2Purity:98%Color and Shape:SolidMolecular weight:438.52PNZ5
CAS:PNZ5, an isoxazole-based pan-BET inhibitor, demonstrates potent activity and high selectivity comparable to the established (+)-JQ1, exhibiting a dissociationFormula:C20H18N2O2Purity:99.51% - 99.61%Color and Shape:SolidMolecular weight:318.37Ref: TM-T12513
1mg109.00€5mg243.00€10mg355.00€25mg532.00€50mg750.00€100mg1,009.00€200mg1,369.00€1mL*10mM (DMSO)240.00€LSD1-IN-12
CAS:LSD1-IN-12 (compound 2) is an effective inhibitor of LSD1, demonstrating inhibitory Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-BFormula:C16H16N2OColor and Shape:SolidMolecular weight:252.31ZLD10A
CAS:ZLD10A is a highly potent and selective small molecule inhibitor of EZH2.Formula:C37H48N4O4Purity:98%Color and Shape:SolidMolecular weight:612.8SMYD2-IN-1
CAS:SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).Formula:C25H25Cl2F2N7O2Purity:98%Color and Shape:SolidMolecular weight:564.41SRTCX1002
CAS:SRTCX1002 is a SIRT1 Activator Suppressing Inflammatory Responses through Promotion of p65 Deacetylation and NF-κB Activity inhibitor.Formula:C21H19N5O2SPurity:98%Color and Shape:SolidMolecular weight:405.47WAY-260022
CAS:WAY-260022 is the norepinephrine transporter inhibitor.Formula:C21H31F3N2O2Purity:97.61% - 99.41%Color and Shape:SolidMolecular weight:400.48HDAC-IN-45
CAS:HDAC-IN-45, a small HDAC blocker, forms H-bonds with Y303 and shows anticancer properties; IC50 for HDAC1/2/3: 0.108/0.585/0.563 μM.Formula:C25H20ClFN8OColor and Shape:SolidMolecular weight:502.93NSC-636819
CAS:NSC-636819 is a novel inhibitor of KDM4A/KDM4B.Formula:C22H12Cl4N2O4Purity:98%Color and Shape:SolidMolecular weight:510.15PU141
CAS:PU141 is a novel inhibitor of histone acetyltransferase (HAT).Formula:C14H9F3N2OSPurity:98%Color and Shape:SolidMolecular weight:310.29CHIC35
CAS:CHIC-35 is a selective deacetylase SIRT1 inhibitor.Formula:C14H15ClN2OColor and Shape:SolidMolecular weight:262.73OTS186935 trihydrochloride
CAS:OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM).Formula:C25H29Cl4N5O2Purity:98%Color and Shape:SolidMolecular weight:573.34ET-JQ1-OH
CAS:ET-JQ1-OH is an allele-specific BET inhibitor.Formula:C21H21ClN4O2SColor and Shape:SolidMolecular weight:428.93dBRD9-A
CAS:Potent BRD9 degrader that binds selectively, fully degrades BRD9 at low doses, and hinders synovial sarcoma growth in vitro and in mice.Formula:C42H49N7O8Color and Shape:SolidMolecular weight:779.88PB118
PB118 clears Aβ, boosts phagocytosis, enhances tubulin networks, reduces p-tau & inflammation in AD; HDAC6 IC50: 5.6 nM.Formula:C18H19FN2O2Color and Shape:SoildMolecular weight:314.35PARP-1/2-IN-1
CAS:PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).Formula:C24H27FN4O3Color and Shape:SolidMolecular weight:438.49CID-4785700
CAS:CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75Formula:C22H23ClFN3O3Purity:98.16%Color and Shape:SolidMolecular weight:431.89Ref: TM-T71740
1mg315.00€5mg873.00€10mg1,080.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,419.00€Y02224
CAS:Y02224 is a BET inhibitor. It shows the reasonable antiproliferative effect on leukemia cells.Formula:C20H17BrN2O4SPurity:98%Color and Shape:SolidMolecular weight:461.33Dot1L-IN-5
CAS:Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein ( DOT1L ) with an IC 50 SPA DOT1L of 0.17 nM [1].Formula:C23H19ClF2N8O5SColor and Shape:SolidMolecular weight:592.96Kgp-IN-1
CAS:Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.Formula:C19H24F4N4O3Purity:98%Color and Shape:SolidMolecular weight:432.41HDAC3-IN-T326
CAS:HDAC3-IN-T326: potent, selective HDAC3 inhibitor, boosts NF-κB acetylation, activates latent HIV gene expression.Formula:C21H18N6O3SPurity:98%Color and Shape:SolidMolecular weight:434.47PS432
CAS:PS432 inhibits atypical PKCs, targets PIF-pocket, reduces tumors in mice sans side effects.Formula:C25H19ClN2O5SPurity:98%Color and Shape:SolidMolecular weight:494.95SIRT5 inhibitor 4
CAS:SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.Formula:C18H15N3O4SPurity:99.97%Color and Shape:SolidMolecular weight:369.39NCD38
CAS:NCD38 is a potent, selective LSD1 inhibitor.Formula:C37H37ClF3N3O4Purity:98.21% - 98.86%Color and Shape:SolidMolecular weight:680.16Helenalin Acetate
CAS:Helenalin Acetate: anti-inflammatory, anti-cancer, hinders C/EBPß and p300 cooperation.Formula:C17H20O5Purity:98%Color and Shape:SolidMolecular weight:304.34DM-01
CAS:DM-01 is a potent and selective inhibitor of EZH2.Formula:C23H24F3N3O2Color and Shape:SolidMolecular weight:431.45(1S,2R)-Tranylcypromine hydrochloride
CAS:(1S,2R)-Tranylcypromine hydrochloride ((1S,2R)-SKF 385), a potent antidepressant, functions by inhibiting both MAO and LSD1.Formula:C9H12ClNColor and Shape:SolidMolecular weight:169.651Akt Inhibitor X
CAS:Akt Inhibitor X is a cell-permeable and reversible inhibitor of Akt phosphorylation.Formula:C20H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:344.88Gue1654
CAS:Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.Formula:C23H17N3OS3Purity:98.02% - 98.04%Color and Shape:SolidMolecular weight:447.6Aurora A/PKC-IN-1
CAS:Aurora A/PKC-IN-1 inhibits AurA (IC50: 6.9 nM), PKCα (IC50: 16.9 nM), and hinders breast cancer cell growth and spread.Formula:C16H14N6OSe2Color and Shape:SolidMolecular weight:464.24JAK-IN-11
CAS:JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.Formula:C23H22FN5O4SPurity:99.75%Color and Shape:SolidMolecular weight:483.52BI-9321
CAS:BI-9321: Selective NSD3-PWWP1 antagonist, Kd 166 nM. Inactive against NSD2-PWWP1/NSD3-PWWP2.Formula:C22H21FN4Purity:98%Color and Shape:SolidMolecular weight:360.43BNS
CAS:BNS is a potent, prolyl-hydroxylase 2 (PHD2)-selective inhibitor.Formula:C18H16N2O6S2Purity:98%Color and Shape:SolidMolecular weight:420.46IACS-9571
CAS:IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).Formula:C32H42N4O8SPurity:98%Color and Shape:SolidMolecular weight:642.76F-amidine
CAS:F-amidine is a bioavailable irreversible PAD4 inactivator.Formula:C14H19FN4O2Color and Shape:SolidMolecular weight:294.32Tyk2-IN-5
CAS:Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).Formula:C21H19FN8O2Purity:98%Color and Shape:SolidMolecular weight:434.43HDAC1-IN-4
CAS:HDAC1-IN-4 is a potent inhibitor of Plasmodium falciparum HDAC1 (PfHDAC1) with low cytotoxicity and antimalarial effects (IC50<5 nM).Formula:C21H24BrClN6O2Color and Shape:SolidMolecular weight:507.82HDAC/NAMPT-IN-1
CAS:HDAC/NAMPT-IN-1 (compound 39h) simultaneously inhibits HDAC and NAMPT, exhibiting IC 50 values ranging from 0.72 to 37081 nM for HDAC and 1618 nM for NAMPT [1].Formula:C19H21N5O2Color and Shape:SolidMolecular weight:351.4UNC0379 TFA
CAS:UNC0379 TFA inhibits SETD8 (IC50: 7.3 μM), selective for 15+ methyltransferases.Formula:C25H36F3N5O4Color and Shape:SolidMolecular weight:527.589NR-160
CAS:NR-160 is a selective HDAC6 inhibitor (IC50=0.03μM), weaker on HDAC1-4,8, toxic to 7 cancer lines, boosts bortezomib and anthracycline effects.Formula:C25H21F3N6O3Color and Shape:SolidMolecular weight:510.47NCGC00247743
CAS:NCGC00247743 is an inhibitor of histone lysine demethylase KDM4.Formula:C24H29N3O2Purity:98%Color and Shape:SolidMolecular weight:391.51
