Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2553 products of "Chromatin/Epigenetics"
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HDAC/HSP90-IN-3
CAS:HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.Formula:C26H33N5O6Color and Shape:SolidMolecular weight:511.57JBI-589
CAS:JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis.Formula:C29H28FN5OColor and Shape:SolidMolecular weight:481.56XDM-CBP
CAS:XDM-CBP is an effective and selective CBP/p300 bromodomain inhibitor.Formula:C21H22N2O4Purity:98%Color and Shape:SolidMolecular weight:366.41JAK-IN-1
CAS:JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.Formula:C20H24N6O2Purity:98%Color and Shape:SolidMolecular weight:380.44INCB059872 tosylate
CAS:INCB059872: potent, selective oral LSD1 inhibitor, increasing tumor-suppressor gene expression by promoting H3K4 and H3K9 methylation.Formula:C37H50N2O9S2Color and Shape:SolidMolecular weight:730.932BRCA1-IN-2
CAS:BRCA1-IN-2 is a cell membrane-crossing BRCA1 protein-protein interaction (PPI) inhibitor with antitumor activity that acts by disrupting the interaction of BRCA1 (BRCT)2 with proteins.Formula:C26H33N4O7PPurity:98.04%Color and Shape:SolidMolecular weight:544.54PIN1 inhibitor 2
CAS:PIN1 inhibitor 2, compound 12, impedes PIN1, shows promise in breast cancer study, and has IC50 of 9.55 μM in MCF7 cells.Formula:C16H21N3S2Color and Shape:SolidMolecular weight:319.49CBB1007
CAS:CBB1007 is a potent, reversible, and substrate competitive LSD1 inhibitor (IC50: 5.27 μM for hLSD1).Formula:C27H34N8O4Purity:98%Color and Shape:SolidMolecular weight:534.61BY27
CAS:BY27 is a BET BD2 inhibitor with anticancer activity that inhibits BRD2, BRD3 and BRD4 and suppresses tumor growth.Formula:C22H21ClN6Purity:99.4% - 99.68%Color and Shape:SolidMolecular weight:404.89CAY10398
CAS:CAY10398 is a compound that serves as an isoform-selective inhibitor of histone deacetylase (HDAC1).Formula:C15H23N3O3Color and Shape:SolidMolecular weight:293.367KF21213
CAS:KF21213 shows a high affinity for the adenosine A2A receptors (Ki=3.0 nM). KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors.Formula:C19H22N4O3Purity:98%Color and Shape:SolidMolecular weight:354.4dBRD4-BD1
CAS:dBRD4-BD1 selectively inhibits and degrades BRD4 (DC50=280nM), upregulates BRD2/3, and aids in creating BRD4-specific probes.Formula:C50H53F3N8O9Color and Shape:SolidMolecular weight:967T-448 free base
CAS:T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).Formula:C17H20N4OSPurity:98%Color and Shape:SolidMolecular weight:328.43Tubulin/JAK2-IN-1
CAS:Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significantFormula:C22H20N6O3Color and Shape:SolidMolecular weight:416.43Compound SA91-0178
CAS:SA91-0178 (3-{[(1-methyl-2-oxo-1'-phenyl-1,2-dihydrospiro[indole-3,4'-piperidine]-5-carbonyl)amino]methyl}benzoic acid) is a specific METTL1 inhibitor and effectively alleviated tissue injury during septic inflammation.Formula:C28H27N3O4Molecular weight:469.54GSK3368715 hydrochloride
CAS:GSK3368715, a first-in-class, orally active, potent, and selective SAM-noncompetitive inhibitor of Type I Protein Arginine Methyltransferases (PRMTs), exhibits anti-tumor efficacy across multiple cancer models and alters exon usage with IC50 values in the lower nM range. It synergizes with GSK3326595 (Type II inhibitor) (Axon 3750) to inhibit tumor growth.Formula:C20H38N4O2·HClColor and Shape:SolidMolecular weight:403AMPK activator 7
CAS:AMPK activator 7 (I-3-24, EC50: 8.8 nM) targets AMPK-related disorders like type 2 diabetes and obesity.
Formula:C23H22F3N3O5Color and Shape:SolidMolecular weight:477.43ARTD3/PARP3-IN-1
CAS:ARTD3/PARP3-IN-1 is a non-selective inhibitor targeting diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3)/PARP3 [1].Formula:C17H16N4O2Color and Shape:SolidMolecular weight:308.33Lin281632
CAS:Lin281632 is an inhibitor of RNA binding protein Lin28 and bromodomain. Lin281632 promotes mESC differentiation.Formula:C15H15N5OPurity:99.84%Color and Shape:SolidMolecular weight:281.31Ref: TM-T27835
1mg34.00€5mg71.00€10mg101.00€25mg212.00€50mg340.00€100mg535.00€500mg1,144.00€1mL*10mM (DMSO)79.00€PARP7-probe-1
CAS:PARP7-probe-1: biotinylated, chemiluminescent PARP7 active site probe for research use.Formula:C36H49F3N8O5SColor and Shape:SolidMolecular weight:762.89
