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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2235 products of "Chromatin/Epigenetics"

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  • AZ505 ditrifluoroacetate
    Targetmol
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    AZ505 ditrifluoroacetate

    CAS:
    <p>AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).</p>
    Formula:C33H40Cl2F6N4O8
    Color and Shape:Solid
    Molecular weight:805.59

    Ref: TM-T10427

  • KDM4-IN-3
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    KDM4-IN-3

    CAS:
    <p>KDM4-IN-3 is a KDM4 inhibitor that is cell-permeable and kills prostate cancer cells at low micromolar concentrations.</p>
    Formula:C17H14N4O
    Color and Shape:Solid
    Molecular weight:290.32

    Ref: TM-T60593

  • GSK778
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    GSK778

    CAS:
    <p>GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.</p>
    Formula:C30H33N5O3
    Purity:98.42%
    Color and Shape:Solid
    Molecular weight:511.61

    Ref: TM-T9703

  • TPOP146
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    TPOP146

    CAS:
    <p>TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).</p>
    Formula:C27H35N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:481.58

    Ref: TM-T17147

  • GSK-J2
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    GSK-J2

    CAS:
    <p>GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.</p>
    Formula:C22H23N5O2
    Purity:97.55%
    Color and Shape:Solid
    Molecular weight:389.45

    Ref: TM-T11476

  • PROTAC EZH2 Degrader-1
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    PROTAC EZH2 Degrader-1

    CAS:
    <p>PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.</p>
    Formula:C54H67N7O8
    Color and Shape:Solid
    Molecular weight:942.15

    Ref: TM-T74602

  • (2R)-Octyl-α-hydroxyglutarate
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    (2R)-Octyl-α-hydroxyglutarate

    CAS:
    <p>(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.</p>
    Formula:C13H24O5
    Color and Shape:Solid
    Molecular weight:260.33

    Ref: TM-T19611

  • Itacitinib adipate
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    Itacitinib adipate

    CAS:
    <p>Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.</p>
    Formula:C32H33F4N9O5
    Color and Shape:Solid
    Molecular weight:699.66

    Ref: TM-T11687

  • Boc-Lys(Ac)-AMC
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    Boc-Lys(Ac)-AMC

    CAS:
    <p>Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).</p>
    Formula:C23H31N3O6
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:445.51

    Ref: TM-T36578

  • SGC-iMLLT
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    SGC-iMLLT

    CAS:
    <p>SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular target</p>
    Formula:C22H24N6O
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:388.47

    Ref: TM-T12886

  • CHZ868
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    CHZ868

    CAS:
    <p>CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.</p>
    Formula:C22H19F2N5O2
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:423.42

    Ref: TM-TQ0061

  • GSK9311
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    GSK9311

    CAS:
    <p>GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).</p>
    Formula:C24H31N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:437.53

    Ref: TM-T13715L

  • GSK2879552
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    GSK2879552

    CAS:
    <p>GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.</p>
    Formula:C23H28N2O2
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:364.48

    Ref: TM-T3677

  • Fenbendazole-d3
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    Fenbendazole-d3

    CAS:
    <p>Fenbendazole-d3 is a deuterated compound of Fenbendazole. Fenbendazole has a CAS number of 43210-67-9. Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.</p>
    Formula:C15H10D3N3O2S
    Color and Shape:Solid
    Molecular weight:302.37

    Ref: TM-TMIJ-0307

  • (±)-1,2-Diolein
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    (±)-1,2-Diolein

    CAS:
    <p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>
    Formula:C39H72O5
    Color and Shape:Solid
    Molecular weight:620.99

    Ref: TM-T40101

  • Pim-1/2 kinase inhibitor 1
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    Pim-1/2 kinase inhibitor 1

    CAS:
    <p>Orally active Pim-1/2 inhibitor blocks kinase phosphorylation; used in prostate cancer research.</p>
    Formula:C11H9NO3S
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:235.26

    Ref: TM-T9229

  • CX-6258 hydrochloride hydrate
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    CX-6258 hydrochloride hydrate

    CAS:
    <p>CX-6258 hydrochloride hydrate is a potent and selective inhibitor of pan-Pim kinase that acts on Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM) and Pim-3 (IC50: 16 nM</p>
    Formula:C26H27Cl2N3O4
    Color and Shape:Solid
    Molecular weight:516.42

    Ref: TM-T63589

  • (R)-GSK-3685032
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    (R)-GSK-3685032

    CAS:
    <p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>
    Formula:C22H24N6OS
    Color and Shape:Solid
    Molecular weight:420.54

    Ref: TM-T39648

  • 2'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
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    2'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride

    CAS:
    <p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>
    Formula:C9H13ClFN3O4
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:281.67

    Ref: TM-TNU0425

  • MS8511 hydrochloride
    Targetmol
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    MS8511 hydrochloride

    CAS:
    <p>MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics.</p>
    Formula:C28H42ClN5O3
    Color and Shape:Solid
    Molecular weight:532.12

    Ref: TM-T204198