Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2440 products of "Chromatin/Epigenetics"
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Vafidemstat
CAS:Vafidemstat (ORY-2001) is a lysine-histone demethylase (LSD1)/MAO-B inhibitor for the study of neurological disorders.Formula:C19H20N4O2Purity:99.53%Color and Shape:SolidMolecular weight:336.39GRK2 Inhibitor 2
CAS:GRK2 Inhibitor 2 (Compound 8h), with an IC50 of 19 nM for GRK2 and 137 nM for Aurora-A, enhances β-AR-mediated cAMP accumulation in GRK2-overexpressing HEK293Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.36GSK737
CAS:GSK737 is a dual inhibitor of BRD4 BD1 and BD2, exhibiting pIC50 values of 5.3 and 7.3, respectively.Formula:C20H21N5O2Purity:98%Color and Shape:SolidMolecular weight:363.41MAK683-CH2CH2COOH
CAS:MAK683-CH2CH2COOH, an EED-targeting chemical, serves as a foundation for EED degrader-1 and PROTAC EED degrader-2 design.Formula:C23H21FN6O3Purity:98%Color and Shape:SolidMolecular weight:448.45MS67
CAS:MS67 selectively degrades WDR5 with a 63 nM Kd, has anticancer effects, and is inactive against other protein classes.Formula:C52H59F4N9O7SColor and Shape:SolidMolecular weight:1030.14PHD-IN-1
CAS:<p>PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of ≤5 nM.</p>Formula:C24H23N7O2Purity:98%Color and Shape:SolidMolecular weight:441.49PIM1-IN-1
CAS:PIM1-IN-1 inhibits PIM1/3 with IC50s: PIM1 (7 nM), PIM2 (5530 nM), PIM3 (70 nM); it has anti-cancer properties.Formula:C25H30N8O2Purity:98%Color and Shape:SolidMolecular weight:474.56Sirt2-IN-5
CAS:Sirt2-IN-5 is a potent inhibitor of SIRT2.Formula:C26H27Cl2N5O3Color and Shape:SolidMolecular weight:528.43BET-IN-16
CAS:BET-IN-16 (Comp I), a bromodomain and extra-terminal (BET) inhibitor, demonstrates anticancer activity by impeding the growth of prostate cancer cells.Formula:C31H25N5O3Purity:98%Color and Shape:SolidMolecular weight:515.56KDM2B-IN-1
CAS:KDM2B-IN-1: Potent, specific KDM2B histone demethylase inhibitor for hyperproliferative disease research.Formula:C21H30N4O2SColor and Shape:SolidMolecular weight:402.56BRD-IN-3
CAS:BRD-IN-3 is a highly potent PCAF bromodomain (BRD) inhibitor (IC50: 7 nM). It also exhibits activity against GCN5 and FALZ.Formula:C21H25N5O3Purity:98%Color and Shape:SolidMolecular weight:395.45GNE-049
CAS:GNE-049 is a highly selective CBP inhibitor (IC50=1.1 nM) that blocks prostate cancer cell proliferation.Formula:C27H32F2N6O2Purity:98.67%Color and Shape:SolidMolecular weight:510.58RTS-V5
CAS:RTS-V5 is a dual inhibitor of HDAC/proteasome (IC50s: 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively).Formula:C27H35N5O6Purity:98%Color and Shape:SolidMolecular weight:525.6GSK-3484862
CAS:Gsk-3484862 is a non covalent inhibitor of DNA methyltransferase DNMT1 with anticancer activity.Formula:C19H19N5OSPurity:99.87% - 99.963%Color and Shape:SolidMolecular weight:365.45Ref: TM-T11469
1mg50.00€5mg119.00€10mg187.00€25mg335.00€50mg512.00€100mg730.00€500mg1,473.00€1mL*10mM (DMSO)215.00€DY-46-2
CAS:DY-46-2 is a DNMT3A inhibitor (IC50: 0.39 ± 0.23 μM) with anticancer activity and is used in cancer and tumor research.Formula:C19H22N6O5SPurity:99.12% - 99.12%Color and Shape:SolidMolecular weight:446.48CW 008
CAS:CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs).a PKA activator.Formula:C21H14F2N6O2Purity:97.39%Color and Shape:SolidMolecular weight:420.37GSK-A
CAS:GSK-A is a Histone Lysine Methyltransferase EZH2 inhibitor.Formula:C21H25N5O2Color and Shape:SolidMolecular weight:379.46FM-479
CAS:<p>FM-479, a structural analog of FM-381, lacks inhibition of JAK3/kinases within 100-300 nM, serving as FM-381's negative control.</p>Formula:C25H26N6O2Purity:98%Color and Shape:SolidMolecular weight:442.523BY27
CAS:BY27 is a BET BD2 inhibitor with anticancer activity that inhibits BRD2, BRD3 and BRD4 and suppresses tumor growth.Formula:C22H21ClN6Purity:99.4% - 99.68%Color and Shape:SolidMolecular weight:404.89CBP/p300-IN-21
CAS:CBP/p300-IN-21 (Compound 5d), a selective inhibitor of CBP/p300 with IC50 values of 0.07 μM for p300 and 1.755 μM for CBP, reduces H3K18Ac levels and inhibitsFormula:C19H16ClNO4Purity:98%Color and Shape:SolidMolecular weight:357.79
