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Telomerase

Telomerase

Telomerase is an enzyme that adds repetitive nucleotide sequences to the ends of chromosomes, known as telomeres, thereby maintaining their length and protecting them from degradation. Telomerase activity is crucial for the indefinite proliferation of cells, particularly in stem cells and cancer cells. Inhibitors of telomerase are of great interest in cancer research, as they can limit the replicative potential of cancer cells, leading to cell death. Conversely, telomerase activators are explored for their potential in anti-aging therapies. At CymitQuimica, we provide a selection of high-quality telomerase inhibitors and activators to support your research in cancer biology, aging, and cellular immortality.

Found 33 products of "Telomerase"

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  • BIBR 1532

    CAS:
    <p>BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).</p>
    Formula:C21H17NO3
    Purity:98.49% - 98.90%
    Color and Shape:Solid
    Molecular weight:331.36
  • BCH001

    CAS:
    <p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>
    Formula:C20H15F3N2O5
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:420.34
  • TMPyP4 tosylate

    CAS:
    <p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>
    Formula:C72H66N8O12S4
    Purity:98.61% - 99.85%
    Color and Shape:Solid
    Molecular weight:1363.6
  • Abacavir sulfate

    CAS:
    <p>Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity</p>
    Formula:C14H18N6OH2O4S
    Purity:99.79% - 99.85%
    Color and Shape:White To Off-White Solid
    Molecular weight:335.38
  • RHPS4

    CAS:
    <p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>
    Formula:C22H17F2N2·CH3O4S
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:458.48
  • 360A

    CAS:
    <p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>
    Formula:C27H23N5O2
    Purity:98.68%
    Color and Shape:Solid
    Molecular weight:449.5
  • Hypericin

    CAS:
    <p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>
    Formula:C30H16O8
    Purity:99.05% - ≥98%
    Color and Shape:Red-Coloured Anthraquinone-Derivative
    Molecular weight:504.44
  • L-778123 hydrochloride

    CAS:
    <p>The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.</p>
    Formula:C22H21Cl2N5O
    Purity:93.93% - 98.51%
    Color and Shape:Solid
    Molecular weight:442.34
  • Cycloastragenol

    CAS:
    <p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>
    Formula:C30H50O5
    Purity:99.85% - 99.92%
    Color and Shape:Solid
    Molecular weight:490.71
  • Remodelin hydrobromide

    CAS:
    <p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>
    Formula:C15H15BrN4S
    Purity:97.22% - 99.84%
    Color and Shape:Solid
    Molecular weight:363.275
  • Antipsychotic agent 54

    CAS:
    <p>Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM).</p>
    Formula:C21H23FN2O4
    Purity:98.10%
    Color and Shape:Solid
    Molecular weight:386.42
  • 7-Deaza-2′-deoxyguanosine 5′-triphosphate

    CAS:
    <p>7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value of 11 μM [1].</p>
    Formula:C11H17N4O13P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.19
  • TERT activator-2

    CAS:
    <p>TERT activator-2 (Compound 1030) is an activator of telomerase reverse transcriptase (TERT), which enhances the expression levels of TERT within cells. TERT activator-2 is applicable to research related to cellular lifespan and telomere functions.</p>
    Formula:C21H22N2O2
    Color and Shape:Solid
    Molecular weight:334.412