CymitQuimica logo
DNA Methyltransferase

DNA Methyltransferase

DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.

Found 422 products of "DNA Methyltransferase"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • 5WKS
    Targetmol
    + Info

    5WKS

    CAS:
    <p>5WKS, or ZINC97756584, is a G9a inhibitor targeting H3K9me2 for gene silencing research in autoimmune diseases and tumors.</p>
    Formula:C24H36ClN5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.03

    Ref: TM-T22250

  • PRMT5-IN-C17
    Targetmol
    + Info

    PRMT5-IN-C17

    CAS:
    <p>PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.</p>
    Formula:C18H17N3O4S
    Color and Shape:Solid
    Molecular weight:371.41

    Ref: TM-T69430

  • BIX-01338 hydrate
    Targetmol
    + Info

    BIX-01338 hydrate

    CAS:
    <p>BIX-01338 hydrate is an inhibitor of histone lysine methyltransferase.</p>
    Formula:C32H26F3N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:621.56

    Ref: TM-T10553

  • CMP-5 hydrochloride
    Targetmol
    + Info

    CMP-5 hydrochloride

    CAS:
    <p>CMP-5 hydrochloride: potent, selective PRMT5 inhibitor; inactive against PRMT1/4/7; blocks S2Me-H4R3 on histones.</p>
    Formula:C21H22ClN3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:351.87

    Ref: TM-T19243

  • Furamidine
    Targetmol
    + Info

    Furamidine

    CAS:
    <p>Furamidine is a PRMT1-selective, cell-permeable inhibitor (IC50: 9.4μM), also targeting TDP-1, and is an antiparasitic bisbenzamidine derivative.</p>
    Formula:C18H16N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:304.35

    Ref: TM-T11338

  • 6-Methyl-5-azacytidine
    Targetmol
    + Info

    6-Methyl-5-azacytidine

    CAS:
    <p>6-Methyl-5-azacytidine is a potent DNMT inhibitor.</p>
    Formula:C9H14N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:258.23

    Ref: TM-T10184

  • Dot1L-IN-7
    Targetmol
    + Info

    Dot1L-IN-7

    CAS:
    <p>Dot1L-IN-7 (compound 25), a potent DOT1L inhibitor with an IC50 of 1.0 μM, selectively kills MLL-AF9, sparing E2A-HLF cells.</p>
    Formula:C23H27N9O2
    Color and Shape:Solid
    Molecular weight:461.52

    Ref: TM-T62915

  • DS-437
    Targetmol
    + Info

    DS-437

    CAS:
    <p>DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.</p>
    Formula:C15H23N7O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:397.45

    Ref: TM-T15169

  • SGC6870
    Targetmol
    + Info

    SGC6870

    CAS:
    <p>SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.</p>
    Formula:C23H21BrN2O2S
    Color and Shape:Solid
    Molecular weight:469.39

    Ref: TM-T69580

  • UNC2327
    Targetmol
    + Info

    UNC2327

    CAS:
    <p>UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).</p>
    Formula:C14H17N5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.38

    Ref: TM-T24926

  • RSC-133
    Targetmol
    + Info

    RSC-133

    CAS:
    promotes the reprogramming of human somatic cells to pluripotent stem cells
    Formula:C18H15N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:305.33

    Ref: TM-T23271

  • DCE_42
    Targetmol
    + Info

    DCE_42

    CAS:
    <p>DCE_42 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.</p>
    Formula:C22H19N9O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:473.51

    Ref: TM-T27130

  • EZH2-IN-3
    Targetmol
    + Info

    EZH2-IN-3

    CAS:
    <p>EZH2-IN-3 is an inhibitor of EZH2 and EZH1 with selective impact on diffuse large B cell lymphoma cell growth.</p>
    Formula:C27H28ClN5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490

    Ref: TM-T25400

  • DC_C66
    Targetmol
    + Info

    DC_C66

    CAS:
    <p>DC_C66 selectively inhibits CARM1 with IC50 of 1.8μM; also affects PRMT1, 6, 5. It's cell-permeable.</p>
    Formula:C28H22NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:404.48

    Ref: TM-T10967

  • Dot1L-IN-5
    Targetmol
    + Info

    Dot1L-IN-5

    CAS:
    <p>Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein ( DOT1L ) with an IC 50 SPA DOT1L of 0.17 nM [1].</p>
    Formula:C23H19ClF2N8O5S
    Color and Shape:Solid
    Molecular weight:592.96

    Ref: TM-T11084

  • OTS186935 trihydrochloride
    Targetmol
    + Info

    OTS186935 trihydrochloride

    CAS:
    OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM).
    Formula:C25H29Cl4N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:573.34

    Ref: TM-T12344L

  • DM-01
    Targetmol
    + Info

    DM-01

    CAS:
    <p>DM-01 is a potent and selective inhibitor of EZH2.</p>
    Formula:C23H24F3N3O2
    Color and Shape:Solid
    Molecular weight:431.45

    Ref: TM-T62403

  • 2′-Deoxy-5-nitrocytidine
    Targetmol
    + Info

    2′-Deoxy-5-nitrocytidine

    CAS:
    <p>2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].</p>
    Formula:C9H12N4O6
    Color and Shape:Solid
    Molecular weight:272.21

    Ref: TM-T60476

  • RM65
    Targetmol
    + Info

    RM65

    CAS:
    <p>RM65 is an arginine methyltransferase inhibitor.</p>
    Formula:C34H32N2O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:596.76

    Ref: TM-T28545

  • SKF 91488 dihydrochloride
    Targetmol
    + Info

    SKF 91488 dihydrochloride

    CAS:
    <p>histamine N-methyltransferase inhibitor</p>
    Formula:C7H19Cl2N3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:248.22

    Ref: TM-T23367