CymitQuimica logo
DNA Methyltransferase

DNA Methyltransferase

DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.

Found 422 products of "DNA Methyltransferase"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • PRMT5-IN-10
    Targetmol
    + Info

    PRMT5-IN-10

    CAS:
    <p>PRMT5-IN-10 exhibits promising structure-dependent inhibitory effect on the protein methyltransferase PRMT5:MEP50 complex.</p>
    Formula:C13H17N5O4
    Color and Shape:Solid
    Molecular weight:307.31

    Ref: TM-T60725

  • EZH2-IN-7
    Targetmol
    + Info

    EZH2-IN-7

    CAS:
    <p>EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.</p>
    Formula:C31H37D2N5O3S
    Color and Shape:Solid
    Molecular weight:563.75

    Ref: TM-T73246

  • 5-Aza-4'-thio-2'-deoxycytidine
    Targetmol
    + Info

    5-Aza-4'-thio-2'-deoxycytidine

    CAS:
    <p>5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].</p>
    Formula:C8H12N4O3S
    Color and Shape:Solid
    Molecular weight:244.27

    Ref: TM-T85478

  • Lobelane Hydrochloride
    Targetmol
    + Info

    Lobelane Hydrochloride

    CAS:
    <p>Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.</p>
    Formula:C22H30ClN
    Color and Shape:Solid
    Molecular weight:343.93

    Ref: TM-T25750

  • Fagaronine chloride
    Targetmol
    + Info

    Fagaronine chloride

    CAS:
    <p>Fagaronine chloride is a potent inhibitor of Topoisomerases I.</p>
    Formula:C21H20ClNO4
    Color and Shape:Solid
    Molecular weight:385.84

    Ref: TM-T27301

  • DC_501
    Targetmol
    + Info

    DC_501

    CAS:
    <p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>
    Formula:C25H23Cl2N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.38

    Ref: TM-T23968

  • Prospasmine
    Targetmol
    + Info

    Prospasmine

    CAS:
    <p>Prospasmine is an anticholinergic.</p>
    Formula:C17H28ClNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:313.87

    Ref: TM-T25995

  • Setin-1
    Targetmol
    + Info

    Setin-1

    CAS:
    <p>Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.</p>
    Formula:C29H21F3N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:486.48

    Ref: TM-T26188

  • DCE_254
    Targetmol
    + Info

    DCE_254

    CAS:
    <p>DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.</p>
    Formula:C21H17N9OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:443.48

    Ref: TM-T27129

  • GSK926
    Targetmol
    + Info

    GSK926

    CAS:
    <p>GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.</p>
    Formula:C29H35N7O2
    Color and Shape:Solid
    Molecular weight:513.63

    Ref: TM-T25470

  • Arazine
    Targetmol
    + Info

    Arazine

    CAS:
    <p>Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.</p>
    Formula:C20H33NO3S
    Purity:90%
    Color and Shape:Solid
    Molecular weight:367.55

    Ref: TM-T10363

  • JNJ-7925476 free base
    Targetmol
    + Info

    JNJ-7925476 free base

    CAS:
    <p>JNJ-7925476 is an TRI antidepressant agent.</p>
    Formula:C20H19N
    Purity:98%
    Color and Shape:Solid
    Molecular weight:273.37

    Ref: TM-T24211

  • (R)-OR-S1
    Targetmol
    + Info

    (R)-OR-S1

    CAS:
    <p>(R)-OR-S1 is a SAM-competitive, highly selective, orally bioavailable dual inhibitor of EZH1/2.</p>
    Formula:C26H34BrN3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:532.47

    Ref: TM-T23575

  • MS453
    Targetmol
    + Info

    MS453

    CAS:
    <p>MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.</p>
    Formula:C20H27N5O3
    Color and Shape:Solid
    Molecular weight:385.46

    Ref: TM-T28116

  • S-Aristeromycinylhomocysteine
    Targetmol
    + Info

    S-Aristeromycinylhomocysteine

    CAS:
    <p>S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.</p>
    Formula:C15H22N6O4S
    Color and Shape:Solid
    Molecular weight:382.44

    Ref: TM-T26177

  • ZLD10A
    Targetmol
    + Info

    ZLD10A

    CAS:
    <p>ZLD10A is a highly potent and selective small molecule inhibitor of EZH2.</p>
    Formula:C37H48N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:612.8

    Ref: TM-T29232

  • LEM-14-1189
    Targetmol
    + Info

    LEM-14-1189

    CAS:
    <p>LEM-14-1189 inhibits NSD1/2/3 (IC50: 418/111/60 μM), targets nuclear receptors, and may treat cancer and blood diseases.</p>
    Formula:C35H34N6O5S2
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:682.81

    Ref: TM-T72979

  • Valemetostat tosylate
    Targetmol
    + Info

    Valemetostat tosylate

    CAS:
    <p>Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.</p>
    Formula:C33H42ClN3O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:660.22

    Ref: TM-T13279

  • MM-102
    Targetmol
    + Info

    MM-102

    CAS:
    <p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>
    Formula:C35H49F2N7O4
    Purity:98.77% - 99.99%
    Color and Shape:Solid
    Molecular weight:669.8

    Ref: TM-T6333

  • EPZ032597
    Targetmol
    + Info

    EPZ032597

    CAS:
    <p>EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and prevent and treat pancreatic cancer</p>
    Formula:C20H23N7O
    Purity:99.70%
    Color and Shape:Solid
    Molecular weight:377.44

    Ref: TM-T70087