DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
Found 422 products of "DNA Methyltransferase"
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Chlorogenic Acid
CAS:Formula:C16H18O9Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:354.31Caffeic Acid
CAS:Formula:C9H8O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:180.161-Hydrazinophthalazine Hydrochloride
CAS:Formula:C8H8N4·HClPurity:>99.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:196.645-Azacytidine
CAS:Formula:C8H12N4O5Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:244.21N-Phthalyl-L-tryptophan
CAS:Formula:C19H14N2O4Purity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Amber to Dark green powder to crystalineMolecular weight:334.33Genistein
CAS:Formula:C15H10O5Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:270.24(-)-Epigallocatechin Gallate Hydrate
CAS:Formula:C22H18O11·xH2OPurity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:458.38 (as Anhydrous)Zebularine
CAS:Formula:C9H12N2O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:228.20Procaine Hydrochloride
CAS:Formula:C13H20N2O2·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:272.77Decitabine
CAS:<p>Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.</p>Formula:C8H12N4O4Purity:98.06% - 99.87%Color and Shape:Physical Description Fine White Crystalline Powder Used As A DrugMolecular weight:228.214-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
CAS:Formula:C8H12N4O4Purity:98%Color and Shape:SolidMolecular weight:228.2053Ref: IN-DA002NLT
1g99.00€5g255.00€10g563.00€25gTo inquire50gTo inquire5mg30.00€100gTo inquire100mg31.00€250mg53.00€A-395
CAS:<p>A-395 blocks PRC2 (EZH2-EED-SUZ12) interactions, strongly inhibiting the complex with an IC50 of 18 nM.</p>Formula:C26H35FN4O2SPurity:98.43%Color and Shape:SolidMolecular weight:486.65Dihydro-5-azacytidine FA
<p>Dihydro-5-azacytidine FA (DHAC) is a pyrimidine analog that has antitumor activity, inhibits cell growth, inhibits DNA methylation, and may be used in the study of malignant mesothelioma.</p>Formula:C9H16N4O7Purity:>99.99%Color and Shape:SolidMolecular weight:292.255-Azacytidine
CAS:<p>5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.</p>Formula:C8H12N4O5Purity:99.31% - 99.79%Color and Shape:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:244.2(E)-3,4-dihydroxycinnamic acid
CAS:Formula:C9H8O4Purity:98%Color and Shape:SolidMolecular weight:180.1574(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate
CAS:Formula:C22H18O11Purity:98%Color and Shape:SolidMolecular weight:458.3717Ref: IN-DA00IK6L
1g22.00€5g24.00€10g31.00€1kg527.00€25g55.00€50g80.00€5kgTo inquire100g114.00€250g177.00€500g302.00€MAK683
CAS:<p>MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).</p>Formula:C20H17FN6OPurity:98.25% - 99.92%Color and Shape:SolidMolecular weight:376.39Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)
CAS:Formula:C8H9ClN4Purity:98%Color and Shape:SolidMolecular weight:196.6369(1S,3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic acid
CAS:Formula:C16H18O9Purity:98%Color and Shape:SolidMolecular weight:354.3087Ref: IN-DA00I681
1g30.00€5g52.00€10g75.00€1kgTo inquire25g153.00€100g489.00€250gTo inquire500gTo inquire50kg41,345.00€250mg26.00€2(1H)-Pyrimidinone, 1-β-D-ribofuranosyl-
CAS:Formula:C9H12N2O5Purity:98%Color and Shape:SolidMolecular weight:228.20204H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
CAS:Formula:C15H10O5Purity:97%Color and Shape:SolidMolecular weight:270.2369Ref: IN-DA00I8G3
1g26.00€5g24.00€10g31.00€1kg686.00€25g52.00€50g77.00€5kgTo inquire100g114.00€10kgTo inquire250g181.00€500g320.00€100mg26.00€BVT948
CAS:<p>BVT948 is a protein tyrosine phosphatase (PTP) inhibitor.It can also inhibit lysine methyltransferase SETD8 (KMT5A) and several cytochrome P450 (P450) isoforms.</p>Formula:C14H11NO3Purity:98.87%Color and Shape:SolidMolecular weight:241.24Diperodon hydrochloride
CAS:<p>Diperodon hydrochloride (Diperocaine) is a local anesthetic that can be broken down by serolytic enzymes to produce local anesthetic effects.</p>Formula:C22H28ClN3O4Purity:99.91%Color and Shape:SolidMolecular weight:433.934-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
CAS:Formula:C8H12N4O5Purity:98%Color and Shape:SolidMolecular weight:244.2047Procaine Hydrochloride
CAS:Formula:C13H21ClN2O2Purity:98%Color and Shape:SolidMolecular weight:272.7710Valemetostat
CAS:<p>Valemetostat (DS-3201) is a first-in-class EZH1/2 dual inhibitor, which can be used to study T-cell lymphoma.Cost-effective and quality-assured.</p>Formula:C26H34ClN3O4Purity:98.38% - 99.08%Color and Shape:SolidMolecular weight:488.02DC-05
CAS:<p>DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).</p>Formula:C25H25N3OPurity:98.95%Color and Shape:SolidMolecular weight:383.49N-Phthalyl-L-tryptophan
CAS:Formula:C19H14N2O4Purity:95%Color and Shape:SolidMolecular weight:334.3255EBI-2511
CAS:<p>EBI-2511 is a highly potent and orally active inhibitor of EZH2 (IC50: 6 nM in Pfeffiera cell lines).</p>Formula:C34H48N4O4Purity:99.74%Color and Shape:SolidMolecular weight:576.77Levetiracetam
CAS:<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Formula:C8H14N2O2Purity:99.67% - 99.86%Color and Shape:White Crystalline PowderMolecular weight:170.21iso-Azalansta
CAS:<p>(2R,4S)-Azalanstat (Iso-Azalansta) is a selective heme oxygenase (HO) inhibitor that is used in the study of cardiovascular disease.</p>Formula:C22H24ClN3O2SPurity:99.53% - 99.89%Color and Shape:SoildMolecular weight:429.96Tulmimetostat
CAS:<p>Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advanced</p>Formula:C28H36ClN3O5SPurity:98.04% - 99.872%Color and Shape:SolidMolecular weight:562.12Amodiaquine dihydrochloride dihydrate
CAS:<p>Amodiaquine dihydrochloride dihydrate (Amodiaquin hydrochloride) is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory effects</p>Formula:C20H28Cl3N3O3Purity:99.97%Color and Shape:SolidMolecular weight:464.82WDR5-47
CAS:<p>WDR5-47 is a potent small molecule to disturb the interaction of MLL1-WDR5 with IC50 value of 0.3μM.</p>Formula:C19H20ClFN4O3Purity:98.15%Color and Shape:SoildMolecular weight:406.84TB22
<p>TB22 is a non-nucleoside inhibitor of DOT1LR231Q with anticancer activity. It inhibits the malignant phenotype of lung cancer cells harboring the R231Q mutation via the MAPK/ERK signaling pathway, making it useful for lung cancer research.</p>Color and Shape:Odour SolidLarsucosterol Ammonium salt
CAS:<p>Larsucosterol ammonium salt is a derivative of 25HC3S. It is a DNMT inhibitor, a LXR antagonist, an endogenous epigenetic modulator of lipid metabolism.</p>Formula:C27H49NO5SPurity:>99.99% - >99.99%Color and Shape:SoildMolecular weight:499.75PRMT5-IN-9
CAS:<p>PRMT5-IN-9 is a novel PRMT5 inhibitor for treating cancer, with an IC 50 of 0.01 μM.</p>Formula:C25H23F3N6OColor and Shape:SolidMolecular weight:480.495UNC6852
CAS:<p>UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.</p>Formula:C43H48N10O6SPurity:96.64%Color and Shape:SolidMolecular weight:832.97EPZ-719
CAS:<p>EPZ-719: Potent SETD2 inhibitor, IC50=0.005μM, high selectivity, potential for targeted epigenetic therapy.</p>Formula:C22H31FN4O3SColor and Shape:SolidMolecular weight:450.57EZH2-IN-5
CAS:<p>EZH2-IN-5, potent EZH2 inhibitor; IC50: 1.52 nM (wild-type), 4.07 nM (Tyr641 mutant).</p>Formula:C26H37BrN4O2Color and Shape:SolidMolecular weight:517.512ML234
<p>ML234 is a dual inhibitor targeting EZH2/LSD1, with IC50 values of 0.09 and 0.12 μM, respectively. It demonstrates strong antiproliferative effects on prostate cancer cell lines LNCAP, PC3, and 22RV1. Additionally, ML234 inhibits tumor growth in a 22RV1 xenograft mouse model, showing potential as a research agent in prostate cancer therapeutics.</p>Color and Shape:Odour SolidPRMT5-IN-11
CAS:<p>PRMT5-IN-11 demonstrates potent structure-dependent inhibition against the protein methyltransferase PRMT5:MEP50 complex at submicromolar concentrations.</p>Formula:C13H17N5O4Color and Shape:SolidMolecular weight:307.31A-893
CAS:<p>A-893 is a cell-active inhibitor of Methyltransferase SMYD2 (IC 50 = 2.8 nM) .</p>Formula:C29H38Cl2N4O4Color and Shape:SolidMolecular weight:577.54UNC2399
CAS:<p>UNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC</p>Formula:C67H104N10O17SColor and Shape:SolidMolecular weight:1353.68C 21
CAS:<p>PRMT1 inhibitor, IC50=1.8μM; 5x more selective than PRMT6; >250x over PRMT3, CARM1.</p>Formula:C90H161ClN36O24Purity:98%Color and Shape:SolidMolecular weight:2166.94SGC3027
<p>SGC3027 is an inhibitor of histone methyltransferase,also is a first potent, selective and cell active chemical probe for PRMT7.</p>Formula:C41H47ClN6O6SPurity:98%Color and Shape:SolidMolecular weight:787.37Dot1L-IN-9
<p>Dot1L-IN-9 (Compound 12) is a DOT1L inhibitor with an IC50 of 125 nM. It effectively reduces H3K79 dimethylation and is utilized in leukemia research.</p>Color and Shape:Odour SolidXF056-132
CAS:<p>XF056-132 is a potent WDR5 (WD40 repeat domain protein 5) PROTAC degrader [1] .</p>Formula:C51H57F4N9O7SColor and Shape:SolidMolecular weight:1016.11
![4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA002NLT.webp&w=3840&q=75)
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