DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
Found 472 products for "DNA Methyltransferase".
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rel-A-395 hydrochloride
CAS:rel-A-395 hydrochloride is the relative configuration of A-395 hydrochloride. A-395 is an antagonist of protein-protein interactions within the polycomb repressive complex 2 (PRC2). It inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 value of 18 nM.Formula:C26H36ClFN4O2SColor and Shape:SolidMolecular weight:523.11SARS-CoV-2 nsp14-IN-1
SARS-CoV-2 nsp14-IN-1 inhibits Nsp14 Mtase with an IC50 of 0.061 μM, affecting multiple substrates.Formula:C20H20N6O5SColor and Shape:SolidMolecular weight:456.48MRK-740-NC
CAS:MRK-740-NC is an inhibitor of the PRDM7/9 histone methyltransferase. Acting as the negative control compound for MRK-740, MRK-740-NC lacks inhibitory activity on PRDM7 and PRDM9 because the methylpyridine portion of MRK-740 is replaced with a phenyl group.Formula:C25H31N5O3Color and Shape:SolidMolecular weight:449.55NSD2-IN-5
CAS:NSD2-IN-5 (Compound 198) is an NSD2 inhibitor with an IC50 value ranging from 0.001 μM to 0.01 μM. It is utilized for cancer research.Formula:C27H25F2N9Molecular weight:513.56HbF inducer-1
HbF inducer-1 is a fetal hemoglobin inducer which is orally bioavailable.Formula:C18H19N3O3Color and Shape:SolidMolecular weight:325.36GSK3368715 dihydrochloride
CAS:GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is a PRMTs inhibitor , with anticancer activity, for the study of advanced solid tumors.Formula:C20H40Cl2N4O2Purity:99.66% - 99.66%Color and Shape:White SolidMolecular weight:439.46ORIC-944
CAS:ORIC-944 is an orally available, selective variant of PRC2 with anticancer activity for the study of prostate cancer.Formula:C26H25FN6OPurity:98.08%Color and Shape:Yellow SolidMolecular weight:456.52Ref: TM-T87073
1mg70.00€5mg137.00€1mL*10mM (DMSO)147.00€10mg197.00€25mg334.00€50mg434.00€100mg655.00€EZM0414
CAS:EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 with IC50 of 18 nM in SETD2 biochemical assay and IC50 of 34 nM in a cellular assay.Formula:C22H29FN4O2Purity:99.58%Color and Shape:SolidMolecular weight:400.49AMG-193
CAS:AMG-193 is an inhibitor of the MTA-PRMT5 complex and is used in the study of cancer, respiratory diseases and digestive disorders.Formula:C22H19F3N4O3Purity:99.92%Color and Shape:SolidMolecular weight:444.41Ref: TM-T85645
10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire1mg50.00€5mg99.00€1mL*10mM (DMSO)109.00€BRD0639
CAS:BRD0639 is a first-in-class PRMT5-substrate interaction inhibitor for PBM-dependent PRMT5 activity studies.Formula:C21H22ClN5O4SPurity:99.85%Color and Shape:SolidMolecular weight:475.95Sinefungin
CAS:Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viralFormula:C15H23N7O5Purity:98% - 98.12%Color and Shape:White SolidMolecular weight:381.39PROTAC EZH2 Degrader-1
CAS:PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.Formula:C54H67N7O8Color and Shape:White SolidMolecular weight:942.15
