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Sirtuin

Sirtuin

Sirtuins are a family of NAD+-dependent deacetylases that play a critical role in regulating cellular processes such as DNA repair, aging, metabolism, and stress resistance. Sirtuins influence DNA repair by deacetylating proteins involved in the repair pathways, thereby modulating their activity. Sirtuin inhibitors and activators are valuable tools in research on aging, cancer, and metabolic diseases, where the regulation of DNA repair and cellular longevity is of interest. At CymitQuimica, we offer a range of high-quality sirtuin modulators to support your research in DNA repair, cellular aging, and metabolic regulation.

Found 86 products of "Sirtuin"

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  • DCHC
    Targetmol
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    DCHC

    CAS:
    DCHC is an activator of SIRT1, but it does not induce SIRT1 expression. This compound can be utilized in studies related to mitochondrial damage.
    Formula:C15H8Cl2O3
    Color and Shape:Solid
    Molecular weight:307.128

    Ref: TM-T204498

    10mg
    To inquire
    50mg
    To inquire
  • SIRT-IN-6
    Targetmol
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    SIRT-IN-6

    CAS:
    SIRT-IN-6 (Compound 14) is a pan-inhibitor of SIRT1/2/3 with an IC50 value of >50 μM. It shows potential as a research agent for studies involving metabolic disorders, inflammation, cancer, and neurodegenerative diseases.
    Formula:C7H4ClN3OS
    Color and Shape:Solid
    Molecular weight:213.644

    Ref: TM-T204971

    10mg
    To inquire
    50mg
    To inquire
  • SIRT1-IN-5
    Targetmol
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    SIRT1-IN-5

    CAS:
    SIRT1-IN-5 (215) is a modulator of NAD-dependent deacetylase SIRT1 with potential applications in cancer and cellular signaling research.
    Formula:C21H17N3O3S
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:391.44

    Ref: TM-T204465

    1mg
    190.00€
    5mg
    471.00€
    10mg
    662.00€
    25mg
    1,036.00€
    50mg
    1,429.00€
    100mg
    1,821.00€
  • SIRT6 activator 2
    Targetmol
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    SIRT6 activator 2

    CAS:
    SIRT6 activator2 (compound 31) is a sirtuin6 activator known for its anti-lipid accumulation properties. It significantly downregulates LXR, SREBP-1c, and their target genes, making it valuable for research into lipid metabolism-related diseases.
    Formula:C23H23N3O6
    Color and Shape:Solid
    Molecular weight:437.45

    Ref: TM-T200625

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • Sirtuin-IN-2
    Targetmol
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    Sirtuin-IN-2

    Sirtuin-IN-2 (compound 20) is an inhibitor of Sirtuin5, a key target in leukemia and breast cancer.
    Formula:C28H46N8O6S
    Color and Shape:Solid
    Molecular weight:622.78

    Ref: TM-T201797

    10mg
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    50mg
    To inquire
  • MDL-811
    Targetmol
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    MDL-811

    CAS:

    MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine residues 9, 18, and 56 (H3K9Ac, H3K18Ac, and H3K56Ac),

    Formula:C25H25BrCl2FN3O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:681.42

    Ref: TM-T81831

    5mg
    Discontinued
    50mg
    Discontinued
    Discontinued product