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Thyroid hormone receptor(THR)

Thyroid hormone receptor(THR)

Thyroid hormone receptors (THRs) are nuclear receptors that mediate the effects of thyroid hormones, which are critical for regulating metabolism, growth, and development. Modulation of THR activity is important in the treatment of thyroid disorders, metabolic syndromes, and certain cancers. THR agonists and antagonists are used in research to study the physiological and pathological roles of thyroid hormones. At CymitQuimica, we offer a wide range of high-quality thyroid hormone receptor modulators to support your research in endocrinology, metabolism, and hormone regulation.

Found 26 products of "Thyroid hormone receptor(THR)"

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  • PCO371
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    PCO371

    CAS:
    <p>PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-</p>
    Formula:C29H32F3N5O6S
    Purity:97.17% - 99.25%
    Color and Shape:Solid
    Molecular weight:635.65

    Ref: TM-T16442

  • 3,5-Diiodothyropropionic acid
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    3,5-Diiodothyropropionic acid

    CAS:
    <p>3,5-Diiodothyropropionic acid: thyroid hormone analog, boosts α-myosin mRNA, binds TRα1 &amp; TRβ1 (Ka: 2.40/M, 4.06/M).</p>
    Formula:C15H12I2O4
    Purity:98.42%
    Color and Shape:Solid
    Molecular weight:510.06

    Ref: TM-T13492

  • Osteostatin
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    Osteostatin

    CAS:
    <p>Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting</p>
    Formula:C27H41N9O8
    Color and Shape:Solid
    Molecular weight:619.67

    Ref: TM-T81592

  • NH-3
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    NH-3

    CAS:
    <p>NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.</p>
    Formula:C28H27NO6
    Purity:97.79% - 99.40%
    Color and Shape:Solid
    Molecular weight:473.52

    Ref: TM-T40548

  • Parathyroid hormone (1-34) (rat)
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    Parathyroid hormone (1-34) (rat)

    CAS:
    <p>Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.</p>
    Formula:C180H291N55O48S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4057.74

    Ref: TM-TP1964

  • DPC-AJ1951
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    DPC-AJ1951

    CAS:
    <p>Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).</p>
    Formula:C76H127N23O19
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1666.98

    Ref: TM-TP1906

  • CymitQuimica logo
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    THR-β agonist 2 diacetate

    <p>THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.</p>
    Color and Shape:Odour Solid

    Ref: TM-T207044

  • CymitQuimica logo
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    DPC-AJ1951 TFA

    <p>DPC-AJ1951 TFA is a 14 amino acid peptide, potent PTH/PPR agonist, tested in bone resorption assays.</p>
    Formula:C78H128F3N23O21
    Color and Shape:Solid
    Molecular weight:1781.02

    Ref: TM-T75942

  • Calcitonin, eel
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    Calcitonin, eel

    CAS:
    <p>Calcitonin from eel regulates calcium and is key in studying postmenopausal osteoporosis.</p>
    Formula:C146H241N43O47S2
    Purity:98%
    Color and Shape:White Powder
    Molecular weight:3414.91

    Ref: TM-TP1028

  • Prepro-TRH-(160-169)
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    Prepro-TRH-(160-169)

    CAS:
    <p>Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.</p>
    Formula:C54H75N11O18S
    Color and Shape:Solid
    Molecular weight:1198.3

    Ref: TM-T76496

  • Taltirelin
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    Taltirelin

    CAS:
    <p>Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in</p>
    Formula:C17H23N7O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:405.41

    Ref: TM-T7590

  • Eprotirome
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    Eprotirome

    CAS:
    <p>Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.</p>
    Formula:C18H17Br2NO5
    Purity:98.42% - 98.56%
    Color and Shape:Solid
    Molecular weight:487.14

    Ref: TM-T5360

  • REVERSE T3
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    REVERSE T3

    CAS:
    <p>Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.</p>
    Formula:C15H12I3NO4
    Purity:95.99% - 97.89%
    Color and Shape:Powder
    Molecular weight:650.97

    Ref: TM-T7578

  • Resmetirom
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    Resmetirom

    CAS:
    <p>Resmetirom (MGL-3196) is a THR-β agonist (EC50=0.21 μM), with high selectivity and oral activity. High-Quality, Low-Cost!</p>
    Formula:C17H12Cl2N6O4
    Purity:99.05% - >99.99%
    Color and Shape:Solid
    Molecular weight:435.22

    Ref: TM-T3595

  • Sobetirome
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    Sobetirome

    CAS:
    <p>Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).</p>
    Formula:C20H24O4
    Purity:98.08% - 98.25%
    Color and Shape:Solid
    Molecular weight:328.4

    Ref: TM-T5313

  • (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
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    (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate

    <p>D-Trp12,Tyr34-pTH(7-34) (bovine) is a PTH antagonist with a Ki of 69 nM in bovine kidneys.</p>
    Purity:96.84%
    Color and Shape:Liquid
    Molecular weight:N/A

    Ref: TM-T9691L

  • 3,3',5-Triiodothyronine-(tyrosine ring-13C6)
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    3,3',5-Triiodothyronine-(tyrosine ring-13C6)

    CAS:
    <p>3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.</p>
    Formula:C4C11H12I3NO4
    Color and Shape:Solid
    Molecular weight:656.93

    Ref: TM-TMID-0106

  • Azetirelin
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    Azetirelin

    CAS:
    <p>Azetirelin, as a TRH analog, has a more potent effect than TRH on the central nervous system.</p>
    Formula:C15H20N6O4
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:348.36

    Ref: TM-T30269

  • KAT681
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    KAT681

    CAS:
    <p>KAT681 is a liver selective thyromimetic.</p>
    Formula:C24H22FNNaO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.429

    Ref: TM-T15644

  • Glutaurine aceate
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    Glutaurine aceate

    <p>Glutaurine aceate containing glutamine and taurine residues is an orally active hormone of the parathyroid.</p>
    Formula:C9H18N2O8S
    Purity:98%
    Color and Shape:Soild
    Molecular weight:314.31

    Ref: TM-T25455L