RAAS
RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.
Found 86 products of "RAAS"
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Trans-Tranilast
CAS:Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It has been used for the treatment of allergic disorders such as atopic dermatitis.Formula:C18H17NO5Purity:99.41% - ≥95%Color and Shape:SolidMolecular weight:327.33Tasosartan
CAS:Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).Formula:C23H21N7OPurity:98.2% - 98.9%Color and Shape:SolidMolecular weight:411.46Ref: TM-T7797
1mg52.00€2mg77.00€5mg113.00€10mg177.00€25mg299.00€50mg447.00€100mg623.00€1mL*10mM (DMSO)124.00€Eprosartan Mesylate
CAS:Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.Formula:C23H24N2O4S·CH4O3SPurity:99.72% - 99.93%Color and Shape:A White To Off- White PowderMolecular weight:520.62Ref: TM-T2531
10mg46.00€25mg65.00€50mg80.00€100mg104.00€200mg161.00€500mg263.00€1mL*10mM (DMSO)46.00€VTP-27999 TFA
CAS:VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).Formula:C28H42ClF3N4O7Purity:98.84%Color and Shape:SolidMolecular weight:639.1Alamandine TFA
Alamandine TFA, a RAS peptide, binds MrgD receptors, has anti-hypertensive effects, and protects heart and kidneys.Formula:C42H63F3N12O11Purity:99.62%Color and Shape:SoildMolecular weight:969.02Azilsartan Medoxomil
CAS:Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adultsFormula:C30H24N4O8Purity:99.83%Color and Shape:SolidMolecular weight:568.53Ref: TM-T6219
1mg38.00€5mg84.00€10mg113.00€25mg200.00€50mg334.00€100mg467.00€200mg643.00€1mL*10mM (DMSO)90.00€Angiotensin III, human, mouse
CAS:Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).Formula:C46H66N12O9Purity:98.44%Color and Shape:SolidMolecular weight:931.09H-Val-Pro-Pro-OH
CAS:H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).Formula:C15H25N3O4Purity:98.23%Color and Shape:SolidMolecular weight:311.38A 779 TFA(159432-28-7 free base)
A 779 TFA is a potent antagonist of angiotensin-(1-7) receptor.Formula:C41H61F3N12O13Purity:99.55%Color and Shape:SolidMolecular weight:987.01Acein acetate
ACE ligand with Kd 2.79 nM, inactive on ACE up to 500 nM. Boosts NMDA/D-serine-induced dopamine release in striatum.Formula:C45H72N10O15Purity:99.43%Color and Shape:SolidMolecular weight:993.11Novokinin acetate
Novokinin acetate binds AT2 receptor (Ki=7 nM); antihypertensive effect blocked by PD123319.Formula:C41H65N11O9Purity:99.37%Color and Shape:SoildMolecular weight:856.02Ref: TM-T23077L
1mg132.00€2mg177.00€5mg289.00€10mg414.00€25mg642.00€50mg853.00€100mg1,161.00€200mg1,558.00€1mL*10mM (DMSO)462.00€SSAA09E2
CAS:SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-Formula:C16H20N4O2Purity:99.41%Color and Shape:SolidMolecular weight:300.36Ref: TM-T9109
1mg37.00€5mg75.00€10mg110.00€25mg245.00€50mg363.00€100mg515.00€200mg700.00€1mL*10mM (DMSO)84.00€Olodanrigan
CAS:Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation.Formula:C32H29NO5Purity:98.33%Color and Shape:SolidMolecular weight:507.58Aviptadil Acetate
CAS:Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs.Formula:C147H238N44O42S·C2H4O2Purity:>99.99%Color and Shape:SolidMolecular weight:3385.9Valsartan
CAS:Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.Formula:C24H29N5O3Purity:99.56% - 99.76%Color and Shape:White Solid PowderMolecular weight:435.52Angiotensin II 5-valine TFA
Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.Formula:C51H70F3N13O14Purity:99.69%Color and Shape:SolidMolecular weight:1146.18Azilsartan Methyl Ester
CAS:Azilsartan Methyl Ester, an angiotensin II blocker, inhibits [125I]AII binding to adrenal cortex; IC50: 0.44uM.Formula:C26H22N4O5Purity:99.87%Color and Shape:SolidMolecular weight:470.48Methyl candesartan
CAS:Methyl candesartan (Candesartan Methyl Ester) 是一种有效的血管紧张素2受体拮抗剂，可用于研究高血压。Formula:C25H22N6O3Purity:98.82%Color and Shape:SolidMolecular weight:454.48Losartan D4
CAS:Losartan D4 (DuP-753 D4) is a deuterated isotope of Losartan for isotopic tracing. Losartan is an angiotensin II receptor antagonist (IC50=20 nM).Formula:C22H23ClN6OPurity:98%Color and Shape:SolidMolecular weight:426.94VTP-27999
CAS:VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.Formula:C26H41ClN4O5Purity:98%Color and Shape:SolidMolecular weight:525.08Pratosartan
CAS:Pratosartan is a selective antagonist of angiotensin II receptor.Formula:C25H26N6OPurity:98%Color and Shape:SolidMolecular weight:426.51L162441
CAS:L162441 is an antagonist of Angiotensin type 1 receptor.Formula:C34H43N5O5SPurity:98%Color and Shape:SolidMolecular weight:633.8Pomisartan
CAS:Pomisartan (BIBR-363) is a small molecule angiotensin type 1 receptor (AT1R) antagonist that is used in the treatment of cardiovascular disease, studying heartFormula:C31H30N4O2Purity:>99.99%Color and Shape:SolidMolecular weight:490.6BMS 183920
CAS:BMS 183920 is a potent Angiotensin II Receptor antagonist that improves improves Caco-2 cell permeability in vivo.Formula:C26H19N5O3Purity:98.92%Color and Shape:SolidMolecular weight:449.46CGP48369
CAS:CGP48369 is a potent angiotensin II receptor antagonist with antihypertensive effects that enhances endothelium-dependent relaxation of coronary arteries inFormula:C26H30N6OPurity:99.27%Color and Shape:SolidMolecular weight:442.56UR-7247
CAS:UR-7247 is an orally active AT1 receptor antagonist with long-lasting effects, high protein binding, and potential application in cardiovascular pharmacology studies.Formula:C24H26N6O2Purity:100% - 98.88%Color and Shape:SolidMolecular weight:430.5ZD-6888 Hydrochloride
CAS:ZD-6888 Hydrochloride, an angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension.Formula:C25H26ClN5OPurity:98.61% - 99.60%Color and Shape:SolidMolecular weight:447.96L-162,313
CAS:L-162,313 is an ANG II receptor agonist, a nonpeptide that mimics the biological actions of angiotensin II and induces an increase in MAP.Formula:C30H38N4O4S2Purity:98.21%Color and Shape:SolidMolecular weight:582.78Buloxibutid
CAS:Buloxibutid: a novel AT2 receptor agonist, Ki=0.4 nM (AT2), 10 μM (AT1).Formula:C23H29N3O4S2Purity:98.24% - 98.58%Color and Shape:SolidMolecular weight:475.62Ref: TM-T14337
1mg47.00€5mg92.00€10mg145.00€25mg260.00€50mg409.00€100mg708.00€500mg1,423.00€1mL*10mM (DMSO)92.00€Terlakiren
CAS:Terlakiren (CP-80,794) is a renin inhibitor that inhibits the potency of human renin and can be used to study neurological disorders of the hypertensive type.Formula:C31H48N4O7SPurity:99.38%Color and Shape:SolidMolecular weight:620.8Ripisartan
CAS:Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.Formula:C23H22N8OPurity:98.52%Color and Shape:SolidMolecular weight:426.47CL-329167
CAS:CL-329167 (compound 12) is an orally active, competitive angiotensin II receptor antagonist (IC50=6 nM) suitable for hypertension research.Formula:C30H32N6O2Purity:99.08% - 99.42%Color and Shape:SolidMolecular weight:508.61KR31173
CAS:KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. When labeled with the 11C isotope, KR31173 can be used as a tracer for positron emission tomography (PET). In mice, KR31173 exhibits favorable biodistribution and pharmacological characteristics. It selectively binds to organs in CD-1 mice known to have a high density of AT1 angiotensin receptors.Formula:C31H30N8O2Color and Shape:SolidMolecular weight:546.62ACT 178882
CAS:ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).Formula:C33H38Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:647.03L162389
CAS:L162389 is an angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor and stimulates the conversion of phosphatidylinositol.Formula:C31H38N4O4SPurity:99.11% - 99.57%Color and Shape:SolidMolecular weight:562.72ZD 7155 hydrochloride
CAS:ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.Formula:C26H27ClN6OPurity:99.8%Color and Shape:SolidMolecular weight:474.98Ref: TM-T13390
1mg42.00€5mg88.00€10mg135.00€25mg235.00€50mg396.00€100mg635.00€200mg887.00€1mL*10mM (DMSO)90.00€
