Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.
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Deoxycorticosterone acetate
CAS:56-47-3
Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection.
Formula:
C23H32O4
Purity:
99% - 99.81%
Color and Shape:
White Solid
Molecular weight:
372.5
Ref: TM-T3033
| 50mg | 48.00 € | ||
| 100mg | 55.00 € | ||
| 200mg | 78.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Cortodoxone
CAS:152-58-9
Cortodoxone (11-Desoxycortisol) is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of …
Formula:
C21H30O4
Purity:
99.26% - 99.87%
Color and Shape:
Solid
Molecular weight:
346.46
Ref: TM-T2748
| 20mg | 47.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Canrenoate potassium
CAS:2181-04-6
Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity.
Formula:
C22H29KO4
Purity:
97.39% - 98.28%
Color and Shape:
Light Yellow To Tan Powder
Molecular weight:
396.56
Ref: TM-T3096
| 100mg | 34.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AL 082D06
CAS:256925-03-8
AL 082D06 (D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding …
Formula:
C23H24ClN3O2
Purity:
99.06% - ≥95%
Color and Shape:
Solid
Molecular weight:
409.91
Ref: TM-T1749
| 5mg | 50.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 154.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 338.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Fludrocortisone acetate
CAS:514-36-3
Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the …
Formula:
C23H31FO6
Purity:
96.92% - 98.03%
Color and Shape:
Crystalline Solid
Molecular weight:
422.49
Ref: TM-T1666
| 100mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Vamorolone
CAS:13209-41-1
Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and …
Formula:
C22H28O4
Purity:
98.04%
Color and Shape:
Solid
Molecular weight:
356.46
Ref: TM-T17217
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 435.00 € | ||
| 200mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Beclometasone
CAS:4419-39-0
Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent …
Formula:
C22H29ClO5
Purity:
99.41% - 99.68%
Color and Shape:
White To Off-White Crystalline Powder
Molecular weight:
408.92
Ref: TM-T8777
| 1ml | 54.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
LY404039
CAS:635318-11-5
LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
Formula:
C7H9NO6S
Purity:
99% - 99.16%
Color and Shape:
Solid
Molecular weight:
235.22
Ref: TM-T6022
| 10mg | 50.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 166.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Apararenone
CAS:945966-46-1
Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat …
Formula:
C17H17FN2O4S
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
364.39
Ref: TM-T14301
| 2mg | 41.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 178.00 € | ||
| 100mg | 257.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Finerenone
CAS:1050477-31-0
Finerenone (BAY-948862) is a selective and orally nonsteroidal antagonist of the mineralocorticoid receptor (MR). Cost …
Formula:
C21H22N4O3
Purity:
99.45% - 99.72%
Color and Shape:
Solid
Molecular weight:
378.42
Ref: TM-T21395
| 1mg | 37.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 348.00 € | ||
| 100mg | 555.00 € | ||
| 200mg | 630.00 € | ||
| 500mg | 924.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Osilodrostat
CAS:928134-65-0
Osilodrostat (LCI699) is a potent inhibitor of human 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2).Cost-effective and …
Formula:
C13H10FN3
Purity:
98% - 99.12%
Color and Shape:
Solid
Molecular weight:
227.24
Ref: TM-T4277
| 1mg | 51.00 € | ||
| 2mg | 66.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 193.00 € | ||
| 50mg | 374.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Fluorometholone
CAS:426-13-1
Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery.
Formula:
C22H29FO4
Purity:
98.21%
Color and Shape:
Solid
Molecular weight:
376.46
Ref: TM-T3316
| 25mg | 52.00 € | ||
| 50mg | 70.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Fluticasone furoate
CAS:397864-44-7
Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.
Formula:
C27H29F3O6S
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
538.58
Ref: TM-T21404
| 4g | 2,663.00 € | ||
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 134.00 € | ||
| 100mg | 183.00 € | ||
| 200mg | 272.00 € | ||
| 500mg | 464.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
AZD9567
CAS:1893415-00-3
AZD9567: potent, selective SGRM, oral, IC50=3.8nM, effective in SCW joint inflammation.
Formula:
C27H28F2N4O3
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
494.53
Ref: TM-T14386
| 1mg | 198.00 € | ||
| 5mg | 503.00 € | ||
| 10mg | 724.00 € | ||
| 25mg | 1,103.00 € | ||
| 50mg | 1,476.00 € | ||
| 100mg | 1,977.00 € | ||
| 1mL*10mM (DMSO) | 560.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Glucocorticoid receptor agonist-1
CAS:2166375-82-0
Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM[1].
Formula:
C35H39NO6
Purity:
99.51%
Color and Shape:
Liquid
Molecular weight:
569.69
Ref: TM-T37908
| 1mg | 210.00 € | ||
| 5mg | 525.00 € | ||
| 10mg | 737.00 € | ||
| 25mg | 1,142.00 € | ||
| 50mg | 1,551.00 € | ||
| 100mg | 2,098.00 € | ||
| 500mg | 4,194.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
PF-3882845
CAS:1023650-66-9
PF-3882845, a high affinity MR antagonist (IC50=2.7 nM) for hypertension, also targets progesterone receptor (IC50: …
Formula:
C24H22ClN3O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
419.9
Ref: TM-T16502
| 1mg | 94.00 € | ||
| 5mg | 189.00 € | ||
| 10mg | 280.00 € | ||
| 25mg | 475.00 € | ||
| 50mg | 794.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
GSK9027
CAS:1229096-88-1
GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than …
Formula:
C27H19F4N3O2S
Purity:
99.36%
Color and Shape:
Solid
Molecular weight:
525.52
Ref: TM-T22818
| 1mg | 59.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 198.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 600.00 € | ||
| 100mg | 828.00 € | ||
| 500mg | 1,663.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Dexamethasone palmitate
CAS:14899-36-6
DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist …
Formula:
C38H59FO6
Purity:
98.08%
Color and Shape:
Solid
Molecular weight:
630.87
Ref: TM-T15102
| 10mg | 49.00 € | ||
| 25mg | 71.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 150.00 € | ||
| 200mg | 216.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
HP210
CAS:728039-52-9
HP210, a selective glucocorticoid receptor modulator (SGRM), can suppress IL-1β and IL-6 mRNA expression, suggesting …
Formula:
C22H19N3O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
421.54
Ref: TM-T78073
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
N-Demethyl Mifepristone
CAS:104004-96-8
N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for …
Formula:
C28H33NO2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
415.57
Ref: TM-T80652
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
