Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.
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Dexamethasone
CAS:50-02-2
Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.
Formula:
C22H29FO5
Purity:
98% - 99.91%
Color and Shape:
Crystals From Ether (Ntp 1992)
Molecular weight:
392.46
Ref: TM-T1076
| 50mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Loteprednol etabonate
CAS:82034-46-6
Loteprednol etabonate (Lotemax) is an ophthalmic analog of the corticosteroid prednisolone with anti-inflammatory activity.
Formula:
C24H31ClO7
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
466.95
Ref: TM-T0181
| 10mg | 46.00 € | ||
| 25mg | 86.00 € | ||
| 50mg | 151.00 € | ||
| 100mg | 237.00 € | ||
| 200mg | 296.00 € | ||
| 500mg | 492.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Rofleponide
CAS:144459-70-1
Rofleponide is a synthetic glucocorticosteroid with a high affinity for the rat thymus glucocorticoid receptor.
Formula:
C25H34F2O6
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
468.53
Ref: TM-T34383
| 1mg | 246.00 € | ||
| 5mg | 606.00 € | ||
| 10mg | 863.00 € | ||
| 25mg | 1,296.00 € | ||
| 50mg | 1,746.00 € | ||
| 100mg | 2,364.00 € | ||
| 500mg | 4,612.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Miricorilant
CAS:1400902-13-7
Miricorilant (CORT 118335) is a glucocorticoid receptor modulator for the study of digestive and metabolic …
Formula:
C24H23F3N2O2
Purity:
98.62%
Color and Shape:
Solid
Molecular weight:
428.45
Ref: TM-T33393
| 1mg | 272.00 € | ||
| 5mg | 670.00 € | ||
| 10mg | 916.00 € | ||
| 25mg | 1,435.00 € | ||
| 50mg | 1,837.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
EX-A5386
CAS:2452396-89-1
EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM.
Formula:
C29H27FN4O2
Purity:
99.69%
Color and Shape:
Soild
Molecular weight:
482.55
Ref: TM-T67742
| 1mg | 87.00 € | ||
| 5mg | 200.00 € | ||
| 10mg | 302.00 € | ||
| 25mg | 504.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
NR3C1 Protein, Human, Recombinant (His)
NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene.
Color and Shape:
Liquid
Molecular weight:
10.95 kDa (predicted)
Ref: TM-TMPY-06836
| 100µg | 687.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Triamcinolone hexacetonide
CAS:5611-51-8
Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a GR agonist used in the study of …
Formula:
C30H41FO7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
532.64
Ref: TM-T17162
| 1mg | 44.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 411.00 € | ||
| 200mg | 605.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Hydrocortisone aceponate
CAS:74050-20-7
Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid used in the form of …
Formula:
C26H36O7
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
460.56
Ref: TM-T32114
| 10mg | 39.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 137.00 € | ||
| 200mg | 184.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Mirodenafil dihydrochloride
CAS:862189-96-6
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
Formula:
C26H39Cl2N5O5S
Purity:
99.27% - 99.64%
Color and Shape:
Solid
Molecular weight:
604.59
Ref: TM-TQ0126
| 5mg | 36.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 129.00 € | ||
| 100mg | 199.00 € | ||
| 500mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Velsecorat
CAS:1196509-60-0
Velsecorat (AZD7594) is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).
Formula:
C32H32F2N4O6
Purity:
99.35%
Color and Shape:
Solid
Molecular weight:
606.62
Ref: TM-TQ0225
| 1mg | 58.00 € | ||
| 2mg | 84.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 786.00 € | ||
| 1mL*10mM (DMSO) | 171.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Fluorometholone Acetate
CAS:3801-06-7
Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive …
Formula:
C24H31FO5
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
418.5
Ref: TM-T6503
| 25mg | 46.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 86.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Corticosterone
CAS:50-22-6
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is …
Formula:
C21H30O4
Purity:
97.25% - ≥95%
Color and Shape:
Solid
Molecular weight:
346.46
Ref: TM-T0948L
| 50mg | 53.00 € | ||
| 100mg | 67.00 € | ||
| 200mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(20S)-Protopanaxatriol
CAS:34080-08-5
(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor …
Formula:
C30H52O4
Purity:
95% - 99%
Color and Shape:
Solid
Molecular weight:
476.73
Ref: TM-T2810
| 5mg | 57.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 243.00 € | ||
| 100mg | 389.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Fluocinonide
CAS:356-12-7
Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin …
Formula:
C26H32F2O7
Purity:
100% - 99.51%
Color and Shape:
Solid
Molecular weight:
494.52
Ref: TM-T6502
| 25mg | 39.00 € | ||
| 50mg | 50.00 € | ||
| 100mg | 71.00 € | ||
| 200mg | 105.00 € | ||
| 500mg | 204.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AZD9977
CAS:1850385-64-6
AZD9977 is a novel, selective modulator of mineralocorticoid receptor .
Formula:
C20H18FN3O5
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
399.37
Ref: TM-T9022
| 1mg | 60.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 707.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Hydrocortisone hemisuccinate
CAS:2203-97-6
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.
Formula:
C25H34O8
Purity:
98.01% - 98.8%
Color and Shape:
Solid
Molecular weight:
462.53
Ref: TM-T4602
| 10mg | 36.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 66.00 € | ||
| 100mg | 85.00 € | ||
| 500mg | 181.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Actriol
CAS:547-81-9
Actriol (Epiestriol) is always used as Glucocorticoid Receptor agonist.
Formula:
C18H24O3
Purity:
95.35% - 95.35%
Color and Shape:
Solid
Molecular weight:
288.38
Ref: TM-T1683
| 1mg | 52.00 € | ||
| 5mg | 98.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Methylprednisolone succinate
CAS:2921-57-5
Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory …
Formula:
C26H34O8
Purity:
98.41% - 99.60%
Color and Shape:
White Or Almost-White Solid Powder
Molecular weight:
474.54
Ref: TM-T22367
| 25mg | 45.00 € | ||
| 50mg | 69.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Ciclesonide
CAS:126544-47-6
Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.
Formula:
C32H44O7
Purity:
100% - 99.94%
Color and Shape:
Solid
Molecular weight:
540.69
Ref: TM-T2526
| 10mg | 52.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 125.00 € | ||
| 100mg | 180.00 € | ||
| 500mg | 446.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Diflorasone
CAS:2557-49-5
Diflorasone is a synthetic glucocorticoid. It has anti-inflammatory and immunosuppressive effects by acting on gene …
Formula:
C22H28F2O5
Purity:
99.02% - 99.92%
Color and Shape:
Solid
Molecular weight:
410.45
Ref: TM-T2548
| 5mg | 42.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 75.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 128.00 € | ||
| 200mg | 174.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
