Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.
Found 165 products of "Glucocorticoid Receptor"
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Spirorenone
CAS:Spirorenone (INN) is a novel aldosterone antagonist with anti-salt corticosteroid activity, used in metabolic disease research.Formula:C24H28O3Purity:98.28% - 99.84%Color and Shape:SolidMolecular weight:364.48Halobetasol
CAS:Halobetasol (Ulobetasol), a corticosteroid, is utilized in the research of severe localized psoriasis [1].Formula:C22H27ClF2O4Purity:98%Color and Shape:SolidMolecular weight:428.9Dagrocorat
CAS:Dagrocorat is a novel and dissociated agonist of glucocorticoid receptor.Formula:C29H29F3N2O2Purity:98%Color and Shape:SolidMolecular weight:494.55Glucocorticoid receptor agonist
CAS:Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist.Formula:C20H20F4N2O2Purity:98%Color and Shape:SolidMolecular weight:396.38Fosdagrocorat
CAS:Fosdagrocorat is an agonist of the dissociated glucocorticoid receptor.Formula:C29H30F3N2O5PColor and Shape:SolidMolecular weight:574.5311β-hydroxy Etiocholanolone
CAS:11β-Hydroxyetiocholanolone, a hydrocortisone metabolite, exhibits elevated fecal levels in giraffes (G. camelopardalis) and plains zebras (E. quagga) in response to environmental stress.Formula:C19H30O3Color and Shape:SolidMolecular weight:306.44RU28362
CAS:RU28362 is an agonist of glucocorticoid receptor.Formula:C23H28O3Color and Shape:SolidMolecular weight:352.4720α-dihydro Prednisolone
CAS:"20α-Dihydro Prednisolone, a prednisolone metabolite, is detected in cattle urine post-adrenocorticotropic hormone (ACTH) administration but absent in both naturally stressed and non-stressed cattle."Formula:C21H30O5Color and Shape:SolidMolecular weight:362.466Amebucort
CAS:Amebucort is a synthetic glucocorticoid corticosteroid. It may used for the research of inflammatory disorders.Formula:C28H40O7Purity:98%Color and Shape:SolidMolecular weight:488.61HP210
CAS:HP210, a selective glucocorticoid receptor modulator (SGRM), can suppress IL-1β and IL-6 mRNA expression, suggesting its utility in investigating inflammation-Formula:C22H19N3O2S2Purity:98%Color and Shape:SolidMolecular weight:421.54Baxdrostat
CAS:Baxdrostat is an aldosterone synthase inhibitor.Formula:C22H25N3O2Purity:99.8%Color and Shape:SolidMolecular weight:363.45Ref: TM-T61373
1mg71.00€5mg152.00€10mg236.00€25mg393.00€50mg550.00€100mg707.00€200mg982.00€1mL*10mM (DMSO)167.00€ORIC-101
CAS:ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.Formula:C34H47NO2Purity:98%Color and Shape:SolidMolecular weight:501.74LEO 134310
CAS:LEO 134310: Selective, non-steroidal GR agonist with 14 nM EC50, for topical skin disease treatment.Formula:C34H40N2O8Color and Shape:SolidMolecular weight:604.69GSK866
CAS:GSK866 is a selective glucocorticoid receptor agonist (SEGRA).Formula:C23H21Cl2F4N5O3Color and Shape:SolidMolecular weight:562.34Dazucorilant
CAS:Dazucorilant (CORT113176), a selective non-steroidal GR modulator, has high affinity with a K i <1 nM, useful for neurological research.Formula:C29H22F4N4O3SColor and Shape:SolidMolecular weight:582.57C108297
CAS:C108297: glucocorticoid modulator, combats diet obesity/inflammation, reduces appetite/lipid storage, boosts fat burn.Formula:C30H36FN3O4SPurity:98%Color and Shape:SolidMolecular weight:553.69Glucocorticoid receptor activator 1
CAS:Glucocorticoid Receptor Activator 1, a phenyl nitrogen-heterocyclic precursor, acts as an activator of the glucocorticoid receptor (GR). By activating GR, it downregulates the expression of pro-inflammatory genes stimulated by TNF, making it useful for inflammation research.Formula:C11H15Cl2NO2Color and Shape:SolidMolecular weight:264.15JTP-117968
CAS:JTP-117968: Non-steroidal SGRM, glucocorticoid receptor modulator, IC50 = 6.8 nM, offers better inhibitory/activatory balance.Formula:C31H31F3N2O2Color and Shape:SolidMolecular weight:520.59S-HP210
S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.Formula:C22H19N3O2S2Color and Shape:SolidMolecular weight:421.54Win 45164
CAS:Win 45164 is an orally active ligand for the glucocorticoid receptor (Glucocorticoid Receptor), exhibiting activity that inhibits the pituitary-adrenal axis. It enhances liver glycogen deposition and thymolysis in adrenalectomized male rats. Additionally, Win 45164 possesses anti-inflammatory properties and is applicable in research related to inflammation and neurological disorders.Formula:C26H27FN2O2Molecular weight:418.503
