Androgen Receptor
The androgen receptor (AR) is a nuclear hormone receptor that is activated by binding to androgens, such as testosterone and dihydrotestosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, as well as in the regulation of several physiological processes, including muscle growth, libido, and bone density. Androgen receptor inhibitors are widely studied in the context of prostate cancer, where AR signaling is often upregulated. At CymitQuimica, we offer a range of high-quality androgen receptor modulators to support your research in endocrinology, cancer biology, and hormone regulation.
Found 229 products of "Androgen Receptor"
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BMS-986365
CAS:BMS-986365 (CC-94676) is an orally available, selective and highly potent AR degrader with potential anticancer activity that inhibits AR signaling and suppresses tumor growth for the study of prostate cancer.Formula:C41H45F3N8O5SPurity:98.69% - 99.96%Color and Shape:SoildMolecular weight:818.91ORM-15341
CAS:ORM-15341 is a potent and full antagonist for human AR (hAR)( with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells)Formula:C19H17ClN6O2Purity:98.01%Color and Shape:SolidMolecular weight:396.83Vosilasarm
CAS:RAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.Formula:C20H16ClN5O2Purity:99.01% - 99.6%Color and Shape:A Crystalline SolidMolecular weight:393.82Topilutamide
CAS:Topilutamide (Fluridil) is a topical nonsteroidal antiandrogen.Formula:C13H11F6N3O5Purity:98.77% - 99.24%Color and Shape:SolidMolecular weight:403.23Ref: TM-T13184
1mg52.00€5mg113.00€10mg178.00€25mg371.00€50mg583.00€100mg830.00€200mg1,134.00€1mL*10mM (DMSO)124.00€Nilutamide
CAS:Nilutamide, a nonsteroidal anti-androgen, treats prostate cancer by blocking androgen receptors, not affecting other hormone receptors.Formula:C12H10F3N3O4Purity:98.67% - 99.78%Color and Shape:Crystalline SolidMolecular weight:317.22Chlormadinone acetate
CAS:Chlormadinone acetate (Gestafortin) is an orally active synthetic progestational hormone used often in combinations as an oral contraceptive.Formula:C23H29ClO4Purity:98.11% - 98.97%Color and Shape:Crystals From Menthanol Or Ether Crystalline SolidMolecular weight:404.93Bicalutamide
CAS:Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting theFormula:C18H14F4N2O4SPurity:98% - 99.87%Color and Shape:Off-White Crystalline SolidMolecular weight:430.37Ligandrol
CAS:Ligandrol is a novel nonsteroidal, oral SARM that binds to the androgen receptor with high affinity (Ki: 1 nM) and selectivity.Formula:C14H12F6N2OPurity:99.94% - >99.99%Color and Shape:SolidMolecular weight:338.253,3'-Diindolylmethane
CAS:3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.Formula:C17H14N2Purity:99.09%Color and Shape:SolidMolecular weight:246.31Zanoterone
CAS:Zanoterone is an AR antagonist (androgen receptor).Zanoterone has antitumor activity for the treatment of genitourinary disorders and oncological disorders and
Formula:C23H32N2O3SPurity:99.03% - 99.92%Color and Shape:SoildMolecular weight:416.58Allylestrenol
CAS:Allylestrenol (Gestanin) is a synthetic steroid with progestational activity.Formula:C21H32OPurity:>99.99%Color and Shape:White Crystalline PowderMolecular weight:300.48Luxdegalutamide
CAS:Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades theFormula:C45H54FN7O6Purity:99.95%Color and Shape:SolidMolecular weight:807.95UT-155
CAS:UT-155 is a selective and potent antagonist of the androgen receptor (AR) (Ki: 267 nM for UT-155 binding to AR-LBD).Formula:C20H15F4N3O2Purity:98.94%Color and Shape:SolidMolecular weight:405.35Ref: TM-T13272
1mg58.00€5mg128.00€10mg197.00€25mg315.00€50mg429.00€100mg610.00€200mg825.00€1mL*10mM (DMSO)141.00€Flutamide
CAS:Flutamide (SCH 13521) is an antiandrogen with about the same potency as cyproterone in rodent and canine species.Formula:C11H11F3N2O3Purity:99.6% - 99.96%Color and Shape:SolidMolecular weight:276.21UT-34
CAS:UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wildFormula:C15H12F4N4O2Purity:98.12%Color and Shape:SolidMolecular weight:356.27Ref: TM-T13273
1mg50.00€5mg113.00€10mg177.00€25mg334.00€50mg505.00€100mg782.00€1mL*10mM (DMSO)124.00€Adrenocorticotropic hormone TFA
Adrenocorticotropic hormone TFA is an adrenocorticotropic hormone involved in neurohormonal regulation of the body.Purity:99.71%Color and Shape:Odour SolidN-Desmethyl-Apalutamide
CAS:N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.Formula:C20H13F4N5O2SPurity:98.6%Color and Shape:SolidMolecular weight:463.41Ref: TM-T12146
1mg111.00€5mg245.00€10mg354.00€25mg532.00€50mg735.00€100mg982.00€200mg1,333.00€1mL*10mM (DMSO)264.00€Ostarine
CAS:Ostarine (MK-2866) is a non-steroidal SARM mimicking testosterone to boost muscle growth, libido, fertility, and may help prevent muscle wasting in cancer.Formula:C19H14F3N3O3Purity:99.69% - 99.90%Color and Shape:SolidMolecular weight:389.33AS-601811
CAS:AS-601811 is a bio-active chemical.Formula:C15H17NOPurity:98.05% - 99.58%Color and Shape:SolidMolecular weight:227.3Adrenosterone
CAS:Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.Formula:C19H24O3Purity:98.13% - 98.29%Color and Shape:SolidMolecular weight:300.39Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formula:C24H32O4SPurity:99.87%Color and Shape:White PowderMolecular weight:416.57SK33
CAS:SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.Formula:C20H13F9N2O3Purity:99.55%Color and Shape:SolidMolecular weight:500.31Ref: TM-T12928
1mg34.00€5mg71.00€10mg110.00€25mg212.00€50mg340.00€100mg550.00€200mg780.00€1mL*10mM (DMSO)90.00€AR antagonist 1
CAS:AR antagonist 1 is a potent antagonist of the androgen receptor.Formula:C15H19ClN2OPurity:99.07%Color and Shape:SolidMolecular weight:278.78Ref: TM-T10359
1mg57.00€5mg118.00€10mg170.00€25mg279.00€50mg371.00€100mg522.00€200mg710.00€1mL*10mM (DMSO)112.00€Andarine
CAS:Andarine (GTx-007) (S-4) is an active partial agonist and an investigational selective androgen receptor modulator (SARM).Formula:C19H18F3N3O6Purity:99.88%Color and Shape:Pale Yellow SolidMolecular weight:441.36Cyproterone acetate
CAS:Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues andFormula:C24H29ClO4Purity:98.43% - 99.83%Color and Shape:Crystals From Diisopropyl Ether OdourMolecular weight:416.94ACP-105
CAS:ACP-105 is a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgenFormula:C16H19ClN2OPurity:99.89%Color and Shape:SolidMolecular weight:290.79Ref: TM-T14116
2mg38.00€5mg58.00€10mg90.00€25mg164.00€50mg226.00€100mg325.00€200mg455.00€1mL*10mM (DMSO)65.00€Medroxyprogesterone Acetate
CAS:Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. Farlutin is a long-acting contraceptive.Formula:C24H34O4Purity:99.05% - 99.44%Color and Shape:White PowderMolecular weight:386.522,2,5,7,8-Pentamethyl-6-Chromanol
CAS:2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation andFormula:C14H20O2Purity:98.72%Color and Shape:SolidMolecular weight:220.31Proxalutamide
CAS:Proxalutamide is a potent antagonist of the androgen receptor (AR).Formula:C24H19F4N5O2SPurity:99.11%Color and Shape:SolidMolecular weight:517.5Ref: TM-T15445
1mg79.00€5mg168.00€10mg258.00€25mg508.00€50mg777.00€100mg1,132.00€200mg1,516.00€1mL*10mM (DMSO)192.00€Octinoxate
CAS:Octinoxate (Octyl 4-methoxycinnamate) is an organic compound that is used is in sunscreens and other cosmetics to absorb UV-B rays from the sun.Formula:C18H26O3Purity:99.93%Color and Shape:Less To Pale Yellow Viscous Liquid (Ntp 1992) Physical Description Colorless To Pale Yellow Viscous Liquid (Ntp 1992)Molecular weight:290.40BWA-6047
BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC-type degrader (AR: DC50= 3.7 nM; AR-V7: DC50= 3.0 nM; GSPT1: DC50= 1.2 nM). It facilitates the ubiquitination and degradation of AR/AR-V7 and, through molecular glue properties, induces a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 is applicable in prostate cancer research.Formula:C42H46ClN5O7Color and Shape:SolidMolecular weight:767.30858Nuclear Receptor Compound Library
A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
Color and Shape:Odour SolidARD-2585
CAS:ARD-2585 is an orally active and selective androgen receptor PROTAC degrader with anticancer activity for the study of prostate cancer.Formula:C41H43ClN8O5Color and Shape:SolidMolecular weight:763.28Tibolone
CAS:Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for theFormula:C21H28O2Purity:99.70% - 99.71%Color and Shape:White To Off-White Crystalline PowderMolecular weight:312.45TD-802
CAS:TD-802, an AR-targeting PROTAC with microsomal stability, shows promise for castration-resistant prostate cancer.Formula:C52H61ClN10O6Color and Shape:SolidMolecular weight:957.56K2-B4-5e
K2-B4-5e is a PROTAC compound designed to target the degradation of BRD4 and androgen receptor (AR) through a KLHDC2-based E3 ligase mechanism. It effectively induces rapid and potent degradation of BET family proteins and AR within cells.Formula:C52H49ClN8O6SMolecular weight:948.31843Cl-4AS-1
CAS:steroidal androgen receptor agonistFormula:C26H33ClN2O2Purity:98%Color and Shape:SolidMolecular weight:441.01Dipropyl phthalate
CAS:Dipropyl phthalate is a weak androgen receptor inhibitor, and can be used in biochemical experiments and drug synthesis.Formula:C14H18O4Purity:98.62%Color and Shape:SolidMolecular weight:250.29PROTAC AR Degrader-9
PROTAC AR Degrader-9 (Compound c6) is a PROTAC-based degrader specifically targeting the androgen receptor. It effectively degrades the androgen receptor in human dermal papilla cells (HDPC) with a DC50 of 262.38 nM. Additionally, this compound enhances the expression of paracrine factors, such as TGF-β1 and β-catenin, thereby promoting hair regeneration in mouse models. [Pink: ligand for target protein AR ligand-38; Black: linker; Blue: ligand for E3 ligase Cereblon]Formula:C43H49ClN6O5Color and Shape:SolidMolecular weight:765.3399,10-Dihydrophenanthrene
CAS:9,10-Dihydrophenanthrene has inhibitory activity against the androgen receptor and can be used in related research in the field of life sciences.Formula:C14H12Purity:98.76%Color and Shape:SolidMolecular weight:180.25ODM-204
CAS:ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).Formula:C20H21F3N4Purity:98%Color and Shape:SolidMolecular weight:374.40Adrenocorticotropic hormone
CAS:ACTH, a polypeptide, is secreted by the pituitary gland and regulates cortisol and androgen.Color and Shape:SolidLambertianic acid
CAS:Lambertianic acid is a bioactive chemical that has anti-allergic and antibacterial effects.Formula:C20H28O3Purity:98%Color and Shape:SolidMolecular weight:316.441ARD-69
ARD-69, a potent PROTAC, degrades AR in prostate cancer, with low DC50 values in AR+ cell lines, and suppresses AR gene expression.Formula:C62H74ClFN8O7SColor and Shape:SolidMolecular weight:1129.83Faznolutamide
CAS:Faznolutamide is an antiandrogen agent [1] [2] .Formula:C19H17FN4O2SColor and Shape:SolidMolecular weight:384.43PROTAC AR Degrader-4 TFA
PROTAC AR Degrader-4: IAP ligand, linker, AR binder; it's a SNIPER that degrades AR non-genetically.Formula:C45H68F3N3O11Color and Shape:SolidMolecular weight:884.03Inocoterone acetate
CAS:Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models.Formula:C18H26O3Color and Shape:SolidMolecular weight:290.40Linuron
CAS:Linuron herbicide disrupts photosynthesis and acts as an androgen receptor antagonist.Formula:C9H10Cl2N2O2Purity:99.08%Color and Shape:White Crystalline Solid Linuron Is A Colorless Crystals Non Corrosive Used As An HerbicideMolecular weight:249.09LO-4-25
LO-4-25 is a covalent degrader targeting the androgen receptor (AR) and its splice variant AR-V7. It covalently binds to the E3 ubiquitin ligase CUL4 DCAF16, facilitating the ubiquitination of both AR and AR-V7, which are then recognized and degraded by the proteasome, leading to reduced protein levels of AR and AR-V7 in cells. LO-4-25 is promising for research on androgen-independent prostate cancer.Color and Shape:Odour Solid3-Cl-Pyridine-amide-acrylaldehyde-piperazine
3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.Color and Shape:Odour Solid
