NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 444 products of "NF-κB"
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γ-Tocotrienol
CAS:<p>γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.</p>Formula:C28H42O2Purity:97.27% - 98.13%Color and Shape:SolidMolecular weight:410.63Ginsenoside Rk3
CAS:<p>Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.</p>Formula:C36H60O8Purity:99.33% - 99.88%Color and Shape:SolidMolecular weight:620.86MLN120B
CAS:<p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>Formula:C19H15ClN4O2Purity:98.92%Color and Shape:SolidMolecular weight:366.8PTP1B-IN-1
CAS:<p>PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)</p>Formula:C8H8N2O3SPurity:99.27%Color and Shape:SolidMolecular weight:212.23MD2-TLR4-IN-1
CAS:<p>MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.</p>Formula:C22H14Cl2N4OPurity:97.74%Color and Shape:SolidMolecular weight:421.28Rubiadin-1-methyl ether
CAS:<p>Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.</p>Formula:C16H12O4Purity:98.32%Color and Shape:SolidMolecular weight:268.26Rhynchophylline
CAS:<p>Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.</p>Formula:C22H28N2O4Purity:99.44% - 99.98%Color and Shape:Red Brown Or White Fine PowderMolecular weight:384.47ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Formula:C11H12O4Purity:97.79%Color and Shape:SolidMolecular weight:208.21GSK583
CAS:<p>GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).</p>Formula:C20H19FN4O2SPurity:98.68% - 99.81%Color and Shape:SolidMolecular weight:398.45Isovitexin
CAS:<p>1.</p>Formula:C21H20O10Purity:99.79% - 99.97%Color and Shape:SolidMolecular weight:432.38Denosumab
CAS:<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Formula:C6404H9912N1724O2004S50Purity:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Color and Shape:LiquidMolecular weight:144.71 kDaJTP 0819958 - HOIPIN-1
<p>JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.</p>Formula:C17H13NaO4Purity:99.95%Color and Shape:SolidMolecular weight:304.27Diethylmaleate
CAS:<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Formula:C8H12O4Purity:98%Color and Shape:Colourless LiquidMolecular weight:172.18Chelidonic acid
CAS:<p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>Formula:C7H4O6Purity:99.03%Color and Shape:SolidMolecular weight:184.1Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Formula:C141H210N32O44SPurity:98%Color and Shape:SolidMolecular weight:3089.43Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formula:C32H22O10Purity:98% - 99.72%Color and Shape:SolidMolecular weight:566.51AZD3264
CAS:<p>AZD3264 is a new type IKK2 inhibitor.</p>Formula:C21H23N5O4SPurity:98.98% - 99.17%Color and Shape:SolidMolecular weight:441.5Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84Rocaglamide
CAS:<p>Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.</p>Formula:C29H31NO7Purity:95.32% - 99.67%Color and Shape:SolidMolecular weight:505.56
