NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 389 products of "NF-κB"
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Rucaparib Phosphate
CAS:Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.Formula:C19H18FN3O·H3PO4Purity:99.37%Color and Shape:SolidMolecular weight:421.36Ref: TM-T6127
1mg35.00€2mg50.00€5mg74.00€1mL*10mM (DMSO)74.00€10mg109.00€25mg178.00€50mg235.00€100mg371.00€200mg553.00€Damascenone
CAS:Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.Formula:C13H18OPurity:99.81%Color and Shape:Colorless LiquidMolecular weight:190.2820(S)-Ginsenoside Rg3
CAS:20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.012,4-Diamino-6-hydroxypyrimidine
CAS:2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesisFormula:C4H6N4OPurity:99.82%Color and Shape:White Solid CrystalsMolecular weight:126.12Andrographolide
CAS:Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potentialFormula:C20H30O5Purity:99.39% - 99.97%Color and Shape:PowderMolecular weight:350.458-Deoxygartanin
CAS:8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it hasFormula:C23H24O5Purity:99.04% - 99.88%Color and Shape:SolidMolecular weight:380.43TAK-243
CAS:TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).Formula:C19H20F3N5O5S2Purity:98.09% - 98.93%Color and Shape:SolidMolecular weight:519.52Ref: TM-T16974
1mg46.00€2mg60.00€5mg90.00€1mL*10mM (DMSO)102.00€10mg142.00€25mg254.00€50mg434.00€100mg623.00€Caffeic Acid Phenethyl Ester
CAS:CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.Formula:C17H16O4Purity:99.18% - 99.35%Color and Shape:Less Transparent Liquid Colorless Transparent LiquidMolecular weight:284.31Betulinic acid
CAS:Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Formula:C30H48O3Purity:98.22% - 99.7%Color and Shape:White Crystalline PowderMolecular weight:456.70Indacaterol
CAS:Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.Formula:C24H28N2O3Purity:99.96%Color and Shape:SolidMolecular weight:392.49Rucaparib monocamsylate
CAS:Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.Formula:C29H34FN3O5SPurity:99.82%Color and Shape:SolidMolecular weight:555.66Tryptanthrin
CAS:Tryptanthrin is a natural DNA gyrase inhibitor.Formula:C15H8N2O2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:248.24Sauchinone
CAS:Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.Formula:C20H20O6Purity:99.12% - >99.99%Color and Shape:SolidMolecular weight:356.37Sanggenon C
CAS:Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.Formula:C40H36O12Purity:97.76% - 99.76%Color and Shape:SolidMolecular weight:708.71Ref: TM-T4S1615
1mg88.00€5mg178.00€10mg268.00€1mL*10mM (DMSO)269.00€25mg467.00€50mg665.00€100mg888.00€200mg1,234.00€HOMOPLANTAGININ
CAS:Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and showsFormula:C22H22O11Purity:97.63% - 99.66%Color and Shape:SolidMolecular weight:462.40SC75741
CAS:SC75741 is a potent P65 inhibitor with IC50 of 200 nMFormula:C29H23N7O2S2Purity:99.44% - 99.54%Color and Shape:SolidMolecular weight:565.67Ref: TM-T6661
1mg40.00€5mg73.00€1mL*10mM (DMSO)93.00€10mg105.00€25mg177.00€50mg281.00€100mg432.00€200mg618.00€Sulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Formula:C6H9NOS2Purity:97.55% - 99.67%Color and Shape:Slightly Yellowish LiquidMolecular weight:175.27Ref: TM-TL0016
1mg34.00€2mg46.00€1mL*10mM (DMSO)65.00€5mg66.00€10mg92.00€25mg167.00€50mg241.00€100mg359.00€200mg525.00€Ginsenoside Rg5
CAS:Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.Formula:C42H70O12Purity:98% - 99.65%Color and Shape:SolidMolecular weight:767.00Ref: TM-T6S1487
1mg107.00€5mg251.00€1mL*10mM (DMSO)341.00€10mg404.00€25mg665.00€50mg888.00€100mg1,251.00€WAY-169916
CAS:WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.Formula:C17H13F3N2O2Purity:98.63% - 98.64%Color and Shape:SolidMolecular weight:334.29Ref: TM-T8981
2mg39.00€5mg60.00€1mL*10mM (DMSO)89.00€10mg92.00€25mg187.00€50mg313.00€100mg450.00€200mg620.00€Astilbin
CAS:Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.Formula:C21H22O11Purity:97% - 99.86%Color and Shape:White PowderMolecular weight:450.39Ref: TM-T2794
5mg49.00€1mL*10mM (DMSO)49.00€10mg73.00€25mg133.00€50mg212.00€100mg316.00€200mg452.00€500mg737.00€
