NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 445 products of "NF-κB"
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Rocaglamide
CAS:<p>Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.</p>Formula:C29H31NO7Purity:95.32% - 99.67%Color and Shape:SolidMolecular weight:505.56Curculigoside
CAS:<p>1.</p>Formula:C22H26O11Purity:99.85%Color and Shape:SolidMolecular weight:466.44Ethacrynic acid
CAS:<p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。</p>Formula:C13H12Cl2O4Purity:98.61% - 99.85%Color and Shape:Crystals Physical Description White Solid (Ntp 1992)Molecular weight:303.14Quinoclamine
CAS:<p>Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.</p>Formula:C10H6ClNO2Purity:99.13% - 99.28%Color and Shape:Orange PowderMolecular weight:207.617,4'-Dihydroxyflavone
CAS:<p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>Formula:C15H10O4Purity:99.39% - 99.6%Color and Shape:SolidMolecular weight:254.24Rucaparib
CAS:<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formula:C19H18FN3OPurity:98.24% - 99.80%Color and Shape:SolidMolecular weight:323.36Geranylgeraniol
CAS:<p>Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.</p>Formula:C20H34OPurity:99.17% - ≥98%Color and Shape:SolidMolecular weight:290.48Adelmidrol
CAS:<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36GSK2982772
CAS:<p>GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.</p>Formula:C20H19N5O3Purity:99.27% - 99.31%Color and Shape:SolidMolecular weight:377.4IRAK inhibitor 1
CAS:<p>IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).</p>Formula:C17H19N5Purity:97.5% - 99.89%Color and Shape:SolidMolecular weight:293.3714-Deoxy-11,12-didehydroandrographolide
CAS:<p>14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.</p>Formula:C20H28O4Purity:99.13% - 99.93%Color and Shape:SolidMolecular weight:332.43Rucaparib Phosphate
CAS:<p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>Formula:C19H18FN3O·H3PO4Purity:99.37%Color and Shape:SolidMolecular weight:421.36Damascenone
CAS:<p>Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.</p>Formula:C13H18OPurity:98.03%Color and Shape:Colorless LiquidMolecular weight:190.28IQ-1S free acid
CAS:<p>IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.</p>Formula:C15H9N3OPurity:97.92% - 99.05%Color and Shape:SolidMolecular weight:247.2520(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.012,4-Diamino-6-hydroxypyrimidine
CAS:<p>2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis</p>Formula:C4H6N4OPurity:99.82%Color and Shape:White Solid CrystalsMolecular weight:126.12Andrographolide
CAS:<p>Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential</p>Formula:C20H30O5Purity:99.39% - 99.97%Color and Shape:PowderMolecular weight:350.458-Deoxygartanin
CAS:<p>8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has</p>Formula:C23H24O5Purity:99.04% - 99.88%Color and Shape:SolidMolecular weight:380.43TAK-243
CAS:<p>TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).</p>Formula:C19H20F3N5O5S2Purity:98.09% - 98.93%Color and Shape:SolidMolecular weight:519.52Caffeic Acid Phenethyl Ester
CAS:<p>CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.</p>Formula:C17H16O4Purity:99.18% - 99.35%Color and Shape:Less Transparent Liquid Colorless Transparent LiquidMolecular weight:284.31
