NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 389 products of "NF-κB"
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Praeruptorin A
CAS:Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulinFormula:C21H22O7Purity:99.63% - 99.65%Color and Shape:SolidMolecular weight:386.4Tenuigenin
CAS:Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.Formula:C30H45ClO6Purity:98.9% - 99.53%Color and Shape:SolidMolecular weight:537.13Ref: TM-T3907
2mg34.00€5mg50.00€10mg73.00€25mg105.00€50mg152.00€100mg215.00€200mg318.00€1mL*10mM (DMSO)63.00€Tectochrysin
CAS:Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.Formula:C16H12O4Purity:99.26%Color and Shape:SolidMolecular weight:268.26INH14
CAS:INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).Formula:C15H16N2OPurity:95.41%Color and Shape:SolidMolecular weight:240.3Picroside II
CAS:Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.Formula:C23H28O13Purity:98% - 99.83%Color and Shape:SolidMolecular weight:512.46Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Formula:C36H56O8Purity:98.55% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:616.83Handelin
CAS:Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.Formula:C32H40O8Purity:99.02% - 99.345%Color and Shape:SolidMolecular weight:552.66Sciadopitysin
CAS:Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.Formula:C33H24O10Purity:98.67% - 99.17%Color and Shape:SolidMolecular weight:580.54Ref: TM-T5S2129
1mg49.00€5mg89.00€10mg154.00€25mg288.00€50mg432.00€100mg620.00€500mg1,279.00€1mL*10mM (DMSO)123.00€Okanin
CAS:Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.Formula:C15H12O6Purity:95.19% - 99.4%Color and Shape:SolidMolecular weight:288.25Ref: TM-TN2008
1mg84.00€5mg245.00€10mg295.00€25mg497.00€50mg710.00€100mg964.00€1mL*10mM (DMSO)207.00€Schisantherin A
CAS:Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.Formula:C30H32O9Purity:98% - 99.989Color and Shape:SolidMolecular weight:536.57Esculentoside H
CAS:Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.Formula:C48H76O21Purity:98.04% - 99.3%Color and Shape:SolidMolecular weight:989.1Isoliquiritin apioside
CAS:Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51Ginsenoside Re
CAS:Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purity:99.12% - >99.99%Color and Shape:White PowderMolecular weight:947.15Ref: TM-T2872
2mg34.00€5mg48.00€10mg63.00€25mg92.00€50mg138.00€100mg197.00€200mg290.00€1mL*10mM (DMSO)65.00€Suberosin
CAS:Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.Formula:C15H16O3Purity:97.08% - 99.26%Color and Shape:SolidMolecular weight:244.29Ref: TM-T5795
2mg37.00€5mg54.00€10mg93.00€25mg167.00€50mg241.00€100mg359.00€200mg525.00€1mL*10mM (DMSO)56.00€NDMC101
CAS:NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.Formula:C13H9ClFNO2Purity:99.89%Color and Shape:SolidMolecular weight:265.67BMS-345541 hydrochloride
CAS:BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).Formula:C14H18ClN5Purity:99.13%Color and Shape:SolidMolecular weight:291.78Ref: TM-T8542
1mg38.00€2mg50.00€5mg82.00€10mg119.00€25mg212.00€50mg356.00€100mg533.00€1mL*10mM (DMSO)52.00€NF-κΒ activator 2
CAS:NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.Formula:C16H11FN2O3Purity:98.12%Color and Shape:SolidMolecular weight:298.27Ref: TM-T39924
1mg94.00€2mg136.00€5mg226.00€10mg335.00€25mg538.00€50mg730.00€100mg938.00€1mL*10mM (DMSO)249.00€Eurycomalactone
CAS:Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.Formula:C19H24O6Purity:99.48% - 99.87%Color and Shape:SolidMolecular weight:348.39JSH-23
CAS:JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.Formula:C16H20N2Purity:98.03% - 99.67%Color and Shape:SolidMolecular weight:240.34Ref: TM-T1930
1mg40.00€2mg54.00€5mg88.00€10mg113.00€25mg177.00€50mg268.00€100mg408.00€1mL*10mM (DMSO)87.00€GS143
CAS:GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.Formula:C28H19FN2O4Purity:97.67%Color and Shape:SolidMolecular weight:466.46Ref: TM-T25465
2mg35.00€5mg55.00€10mg87.00€25mg161.00€50mg245.00€100mg358.00€200mg520.00€1mL*10mM (DMSO)57.00€
