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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 445 products of "NF-κB"

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  • Vamorolone
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    Vamorolone

    CAS:
    <p>Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.</p>
    Formula:C22H28O4
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:356.46

    Ref: TM-T17217

  • Robinin
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    Robinin

    CAS:
    <p>Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.</p>
    Formula:C33H40O19
    Purity:98.78% - 99.13%
    Color and Shape:Solid
    Molecular weight:740.66

    Ref: TM-T2S0265

  • Engeletin
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    Engeletin

    CAS:
    <p>1.</p>
    Formula:C21H22O10
    Purity:99.72% - 99.99%
    Color and Shape:Solid
    Molecular weight:434.39

    Ref: TM-T6S0840

  • Polygalasaponin F
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    Polygalasaponin F

    CAS:
    <p>Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.</p>
    Formula:C53H86O23
    Purity:98% - 99.83%
    Color and Shape:Solid
    Molecular weight:1091.24

    Ref: TM-T3826

  • Embelin
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    Embelin

    CAS:
    <p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>
    Formula:C17H26O4
    Purity:97.07% - 99.88%
    Color and Shape:Solid
    Molecular weight:294.39

    Ref: TM-T6485

  • Triptolide
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    Triptolide

    CAS:
    <p>Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.</p>
    Formula:C20H24O6
    Purity:97.19% - 99.97%
    Color and Shape:White To Off-White Solid
    Molecular weight:360.4

    Ref: TM-T2179

  • Barlerin
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    Barlerin

    CAS:
    <p>Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose deprivation-induced injury</p>
    Formula:C19H28O12
    Purity:99.83% - ≥95%
    Color and Shape:Solid
    Molecular weight:448.42

    Ref: TM-T5S1632

  • TBK1/IKKε-IN-5
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    TBK1/IKKε-IN-5

    CAS:
    <p>TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).</p>
    Formula:C28H31N7O3
    Purity:98.77%
    Color and Shape:Solid
    Molecular weight:513.59

    Ref: TM-T7951

  • Mollugin
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    Mollugin

    CAS:
    <p>Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.</p>
    Formula:C17H16O4
    Purity:99.87% - ≥95%
    Color and Shape:Solid
    Molecular weight:284.31

    Ref: TM-T3673

  • Tyrosol
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    Tyrosol

    CAS:
    <p>Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present most</p>
    Formula:C8H10O2
    Purity:99.24% - 99.86%
    Color and Shape:Solid
    Molecular weight:138.16

    Ref: TM-T2861

  • PI-1840
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    PI-1840

    CAS:
    <p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>
    Formula:C22H26N4O3
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:394.47

    Ref: TM-T6941

  • SM-7368
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    SM-7368

    CAS:
    <p>The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.</p>
    Formula:C10H5ClN4O5S
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:328.69

    Ref: TM-T22115

  • IRAK-1-4 Inhibitor I
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    IRAK-1-4 Inhibitor I

    CAS:
    <p>IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.</p>
    Formula:C20H21N5O4
    Purity:98% - 99.89%
    Color and Shape:Solid
    Molecular weight:395.41

    Ref: TM-T2457

  • Tomatidine
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    Tomatidine

    CAS:
    <p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>
    Formula:C27H45NO2
    Purity:99.94% - 99.98%
    Color and Shape:Solid
    Molecular weight:415.65

    Ref: TM-TMA0507

  • 11-​Keto-​β-​boswellic acid
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    11-​Keto-​β-​boswellic acid

    CAS:
    <p>11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.</p>
    Formula:C30H46O4
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:470.68

    Ref: TM-TN1182

  • RIPA-56
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    RIPA-56

    CAS:
    <p>RIPA-56 is an inhibitor of RIP1</p>
    Formula:C13H19NO2
    Purity:99.53% - 99.93%
    Color and Shape:Solid
    Molecular weight:221.3

    Ref: TM-T7795

  • Zimlovisertib
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    Zimlovisertib

    CAS:
    <p>Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4).</p>
    Formula:C18H20FN3O4
    Purity:98.21%
    Color and Shape:Solid
    Molecular weight:361.37

    Ref: TM-TQ0167

  • Malachite green oxalate
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    Malachite green oxalate

    CAS:
    <p>Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.</p>
    Formula:C23H25N2·C2HO4C2H2O4
    Color and Shape:Dark Green Crystals With A Metallic Luster
    Molecular weight:463.51

    Ref: TM-TD0099

  • Sarsasapogenin
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    Sarsasapogenin

    CAS:
    <p>Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.</p>
    Formula:C27H44O3
    Purity:90% - 99.73%
    Color and Shape:White Or Off-Withe Powder
    Molecular weight:416.64

    Ref: TM-T2733

  • Obtusifolin
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    Obtusifolin

    CAS:
    <p>Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.</p>
    Formula:C16H12O5
    Purity:99.78% - 99.99%
    Color and Shape:Solid
    Molecular weight:284.26

    Ref: TM-T4S0969