NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 398 products of "NF-κB"
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Stachydrine
CAS:Stachydrine, found in leonurus herb, aids blood flow, blocks NF-κB pathway, and indicates citrus intake.
Formula:C7H13NO2Purity:99.94% - ≥95%Color and Shape:SolidMolecular weight:143.18Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Formula:C42H72O14Purity:99.42% - 99.65%Color and Shape:SolidMolecular weight:801.01Neochlorogenic acid
CAS:Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.Formula:C16H18O9Purity:99.12% - 99.54%Color and Shape:White PowderMolecular weight:354.31Ref: TM-T6S1538
1mg34.00€5mg71.00€10mg90.00€25mg147.00€50mg208.00€100mg309.00€200mg447.00€1mL*10mM (DMSO)77.00€Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Formula:C13H15NO2SPurity:99.76% - 99.94%Color and Shape:White SolidMolecular weight:249.33Ref: TM-T1934
2mg35.00€5mg50.00€10mg66.00€25mg85.00€50mg124.00€100mg197.00€200mg255.00€1mL*10mM (DMSO)62.00€BMS-345541
CAS:BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.Formula:C14H17N5Purity:99.36% - 99.74%Color and Shape:SolidMolecular weight:255.32Sulfuretin
CAS:Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.
Formula:C15H10O5Purity:98.91% - 99.86%Color and Shape:SolidMolecular weight:270.241-Caffeoylquinic acid
CAS:1-Caffeoylquinic acid: a lignin precursor with anti-influenza, antioxidant properties, and moderates post-meal glucose release.Formula:C16H18O9Purity:99.15% - 99.16%Color and Shape:SolidMolecular weight:354.31BEC hydrochloride
CAS:BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II.Formula:C5H12BNO4S·ClHPurity:98.65% - 99.28%Color and Shape:SolidMolecular weight:229.49Ref: TM-T6779
1mg39.00€5mg88.00€10mg153.00€25mg283.00€50mg464.00€100mg663.00€200mg919.00€1mL*10mM (DMSO)88.00€2,5-Dihydroxyacetophenone
CAS:2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.Formula:C8H8O3Purity:99.75%Color and Shape:Yellow PowderMolecular weight:152.15Triacetylresveratrol
CAS:Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.
Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formula:C27H30O14Purity:98.11% - 98.58%Color and Shape:SolidMolecular weight:578.52QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formula:C22H20N4OPurity:99.17% - 99.18%Color and Shape:White SolidMolecular weight:356.42Ref: TM-T6204
1mg43.00€2mg57.00€5mg93.00€10mg140.00€25mg188.00€50mg329.00€100mg490.00€200mg710.00€1mL*10mM (DMSO)93.00€TOMATIDINE HYDROCHLORIDE
CAS:Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.Formula:C27H46ClNO2Purity:99.75% - ≥95%Color and Shape:SolidMolecular weight:452.11IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormula:C22H23N5O8Purity:97.73%Color and Shape:SolidMolecular weight:485.45Ref: TM-T9010
1mg40.00€5mg96.00€10mg135.00€25mg226.00€50mg320.00€100mg434.00€200mg602.00€1mL*10mM (DMSO)131.00€Dendrophenol
CAS:Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.Formula:C17H20O5Purity:98.2% - 99.36%Color and Shape:SolidMolecular weight:304.34Ref: TM-T3S1707
1mg99.00€2mg138.00€5mg215.00€10mg319.00€25mg530.00€50mg755.00€100mg1,018.00€1mL*10mM (DMSO)234.00€SC-514
CAS:SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.
Formula:C9H8N2OS2Purity:99.88% - >99.99%Color and Shape:SolidMolecular weight:224.3Morusin
CAS:Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.Formula:C25H24O6Purity:98.68% - 99.8%Color and Shape:SolidMolecular weight:420.45CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Formula:C20H28O3Purity:97.06% - 99.08%Color and Shape:SolidMolecular weight:316.43EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Formula:C18H18ClMnN2O4Purity:98.39%Color and Shape:SolidMolecular weight:416.743'-Sialyllactose
CAS:3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.Formula:C23H39NO19Color and Shape:SolidMolecular weight:633.55
