NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Ginsenoside Rk3
CAS:364779-15-7
Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.
Formula:
C36H60O8
Purity:
99.33% - 99.88%
Color and Shape:
Solid
Molecular weight:
620.86
Ref: TM-T6S1495
| 1mg | 83.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 417.00 € | ||
| 50mg | 616.00 € | ||
| 100mg | 878.00 € | ||
| 1mL*10mM (DMSO) | 281.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
MLN120B
CAS:783348-36-7
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).
Formula:
C19H15ClN4O2
Purity:
98.92%
Color and Shape:
Solid
Molecular weight:
366.8
Ref: TM-TQ0306
| 1mg | 49.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 323.00 € | ||
| 50mg | 557.00 € | ||
| 100mg | 759.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Rubiadin-1-methyl ether
CAS:7460-43-7
Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.
Formula:
C16H12O4
Purity:
98.32%
Color and Shape:
Solid
Molecular weight:
268.26
Ref: TM-T4237
| 1mg | 47.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 439.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Rhynchophylline
CAS:76-66-4
Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory …
Formula:
C22H28N2O4
Purity:
99.44%
Color and Shape:
Red Brown Or White Fine Powder
Molecular weight:
384.47
Ref: TM-T6S0659
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 181.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
ETHYL CAFFEATE
CAS:102-37-4
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in …
Formula:
C11H12O4
Purity:
97.79%
Color and Shape:
Solid
Molecular weight:
208.21
Ref: TM-T5681
| 10mg | 48.00 € | ||
| 25mg | 80.00 € | ||
| 50mg | 120.00 € | ||
| 100mg | 185.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
GSK583
CAS:1346547-00-9
GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).
Formula:
C20H19FN4O2S
Purity:
98.68% - 99.06%
Color and Shape:
Solid
Molecular weight:
398.45
Ref: TM-T3537
| 1mg | 50.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 314.00 € | ||
| 50mg | 456.00 € | ||
| 100mg | 678.00 € | ||
| 500mg | 1,412.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Isovitexin
CAS:38953-85-4
1.
Formula:
C21H20O10
Purity:
98.24% - 99.79%
Color and Shape:
Solid
Molecular weight:
432.38
Ref: TM-T6S1371
| 1mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 587.00 € | ||
| 500mg | 1,198.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Denosumab
CAS:615258-40-7
Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK …
Formula:
C6404H9912N1724O2004S50
Purity:
99.90% - SDS-PAGE:95.4%;SEC-HPLC:98.4%
Color and Shape:
Solid
Molecular weight:
147 kDa
Ref: TM-T9917
| 1mg | 171.00 € | ||
| 5mg | 502.00 € | ||
| 10mg | 720.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
JTP 0819958 - HOIPIN-1
JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.
Formula:
C17H13NaO4
Purity:
95.08%
Color and Shape:
Solid
Molecular weight:
304.27
Ref: TM-T8951
| 5mg | 44.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 304.00 € | ||
| 200mg | 436.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Diethylmaleate
CAS:141-05-9
Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting …
Formula:
C8H12O4
Purity:
98%
Color and Shape:
Colourless Liquid
Molecular weight:
172.18
Ref: TM-T21480
| 100mg | 48.00 € | ||
| 200mg | 74.00 € | ||
| 500mg | 120.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Chelidonic acid
CAS:99-32-1
Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory …
Formula:
C7H4O6
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
184.1
Ref: TM-T5558
| 50mg | 39.00 € | ||
| 100mg | 52.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Ac2-26 acetate
Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).
Formula:
C141H210N32O44S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
3089.43
Ref: TM-TP1373L
| 1mg | 300.00 € | ||
| 5mg | 809.00 € | ||
| 10mg | 1,213.00 € | ||
| 25mg | 2,183.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Sinomenine
CAS:115-53-7
Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the …
Formula:
C19H23NO4
Purity:
99.02% - 99.89%
Color and Shape:
White Powder
Molecular weight:
329.39
Ref: TM-T2726
| 100mg | 59.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
ISOGINKGETIN
CAS:548-19-6
ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.
Formula:
C32H22O10
Purity:
98% - 99.72%
Color and Shape:
Solid
Molecular weight:
566.51
Ref: TM-T4S21320
| 5mg | 52.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
AZD3264
CAS:1609281-86-8
AZD3264 is a new type IKK2 inhibitor.
Formula:
C21H23N5O4S
Purity:
98.98% - 99.17%
Color and Shape:
Solid
Molecular weight:
441.5
Ref: TM-T6771
| 2mg | 44.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 291.00 € | ||
| 100mg | 466.00 € | ||
| 200mg | 637.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
GSK2983559 active metabolite
CAS:1423186-80-4
GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
Formula:
C21H22N4O4S2
Purity:
97.07% - 98.48%
Color and Shape:
Solid
Molecular weight:
458.55
Ref: TM-T5401
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 270.00 € | ||
| 50mg | 503.00 € | ||
| 100mg | 725.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
NF-κΒ activator 2
CAS:2375281-44-8
NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an …
Formula:
C16H11FN2O3
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
298.27
Ref: TM-T39924
| 1mg | 90.00 € | ||
| 2mg | 131.00 € | ||
| 5mg | 218.00 € | ||
| 10mg | 324.00 € | ||
| 25mg | 520.00 € | ||
| 50mg | 704.00 € | ||
| 100mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 240.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Eurycomalactone
CAS:23062-24-0
Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, …
Formula:
C19H24O6
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
348.39
Ref: TM-TN1637
| 1mg | 142.00 € | ||
| 5mg | 331.00 € | ||
| 10mg | 490.00 € | ||
| 25mg | 780.00 € | ||
| 50mg | 1,051.00 € | ||
| 1mL*10mM (DMSO) | 261.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
JSH-23
CAS:749886-87-1
JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 …
Formula:
C16H20N2
Purity:
98.03% - 99.67%
Color and Shape:
Solid
Molecular weight:
240.34
Ref: TM-T1930
| 1mg | 42.00 € | ||
| 2mg | 61.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 189.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 421.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
GS143
CAS:916232-21-8
GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.
Formula:
C28H19FN2O4
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
466.46
Ref: TM-T25465
| 2mg | 37.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 528.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
