NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Rubiadin-1-methyl ether
CAS:7460-43-7
Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.
Formula:
C16H12O4
Purity:
98.32%
Color and Shape:
Solid
Molecular weight:
268.26
Ref: TM-T4237
| 1mg | 48.00 € | ||
| 5mg | 154.00 € | ||
| 10mg | 264.00 € | ||
| 25mg | 449.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Rhynchophylline
CAS:76-66-4
Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory …
Formula:
C22H28N2O4
Purity:
99.44%
Color and Shape:
Red Brown Or White Fine Powder
Molecular weight:
384.47
Ref: TM-T6S0659
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 183.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
ETHYL CAFFEATE
CAS:102-37-4
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in …
Formula:
C11H12O4
Purity:
97.79%
Color and Shape:
Solid
Molecular weight:
208.21
Ref: TM-T5681
| 10mg | 48.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 188.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GSK583
CAS:1346547-00-9
GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).
Formula:
C20H19FN4O2S
Purity:
98.68% - 99.06%
Color and Shape:
Solid
Molecular weight:
398.45
Ref: TM-T3537
| 1mg | 50.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 190.00 € | ||
| 25mg | 319.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 690.00 € | ||
| 500mg | 1,444.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Isovitexin
CAS:38953-85-4
1.
Formula:
C21H20O10
Purity:
98.24% - 99.79%
Color and Shape:
Solid
Molecular weight:
432.38
Ref: TM-T6S1371
| 1mg | 52.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 411.00 € | ||
| 100mg | 597.00 € | ||
| 500mg | 1,225.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Denosumab
CAS:615258-40-7
Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK …
Formula:
C6404H9912N1724O2004S50
Purity:
98.4% (SEC-HPLC) - 99.90%
Color and Shape:
Liquid
Molecular weight:
144.71 kDa
Ref: TM-T9917
| 1mg | 170.00 € | ||
| 5mg | 510.00 € | ||
| 10mg | 737.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
JTP 0819958 - HOIPIN-1
JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.
Formula:
C17H13NaO4
Purity:
95.08%
Color and Shape:
Solid
Molecular weight:
304.27
Ref: TM-T8951
| 1mg | 39.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 523.00 € | ||
| 500mg | 1,159.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Diethylmaleate
CAS:141-05-9
Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting …
Formula:
C8H12O4
Purity:
98%
Color and Shape:
Colourless Liquid
Molecular weight:
172.18
Ref: TM-T21480
| 100mg | 48.00 € | ||
| 200mg | 74.00 € | ||
| 500mg | 122.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Chelidonic acid
CAS:99-32-1
Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory …
Formula:
C7H4O6
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
184.1
Ref: TM-T5558
| 50mg | 39.00 € | ||
| 100mg | 52.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Ac2-26 acetate
Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).
Formula:
C141H210N32O44S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
3089.43
Ref: TM-TP1373L
| 1mg | 301.00 € | ||
| 5mg | 815.00 € | ||
| 10mg | 1,220.00 € | ||
| 25mg | 2,197.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Sinomenine
CAS:115-53-7
Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the …
Formula:
C19H23NO4
Purity:
99.02% - 99.89%
Color and Shape:
White Powder
Molecular weight:
329.39
Ref: TM-T2726
| 100mg | 55.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
ISOGINKGETIN
CAS:548-19-6
ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.
Formula:
C32H22O10
Purity:
98% - 99.72%
Color and Shape:
Solid
Molecular weight:
566.51
Ref: TM-T4S21320
| 5mg | 52.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
AZD3264
CAS:1609281-86-8
AZD3264 is a new type IKK2 inhibitor.
Formula:
C21H23N5O4S
Purity:
98.98% - 99.17%
Color and Shape:
Solid
Molecular weight:
441.5
Ref: TM-T6771
| 1mg | 52.00 € | ||
| 2mg | 70.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 805.00 € | ||
| 500mg | 1,605.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Astaxanthin
CAS:472-61-7
Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used …
Formula:
C40H52O4
Purity:
95.17% - 99.79%
Color and Shape:
Needles From Acetone/Light Petroleum Solid
Molecular weight:
596.84
Ref: TM-T3138
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 131.00 € | ||
| 100mg | 187.00 € | ||
| 500mg | 462.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Rocaglamide
CAS:84573-16-0
Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.
Formula:
C29H31NO7
Purity:
95.32% - 98.46%
Color and Shape:
Solid
Molecular weight:
505.56
Ref: TM-TQ0131
| 500µg | 160.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Curculigoside
CAS:85643-19-2
1.
Formula:
C22H26O11
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
466.44
Ref: TM-T6S1966
| 1mg | 47.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 226.00 € | ||
| 100mg | 340.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Ethacrynic acid
CAS:58-54-8
Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。
Formula:
C13H12Cl2O4
Purity:
100% - 99.15%
Color and Shape:
Crystals Physical Description White Solid (Ntp 1992)
Molecular weight:
303.14
Ref: TM-T4564
| 25mg | 37.00 € | ||
| 50mg | 52.00 € | ||
| 100mg | 70.00 € | ||
| 500mg | 145.00 € | ||
| 1mL*10mM (DMSO) | 38.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Schisantherin A
CAS:58546-56-8
Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.
Formula:
C30H32O9
Purity:
98% - 99.85%
Color and Shape:
Solid
Molecular weight:
536.57
Ref: TM-T2913
| 20mg | 66.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
Necrostatin 2 racemate
CAS:852391-15-2
Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.
Formula:
C13H12ClN3O2
Purity:
98% - 99.50%
Color and Shape:
Solid
Molecular weight:
277.71
Ref: TM-T7504
| 1mg | 65.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 527.00 € | ||
| 100mg | 743.00 € | ||
| 500mg | 1,510.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GSK872 HCl(1346546-69-7 free base)
CAS:2703752-81-0
GSK872 HCl(1346546-69-7 free base) (GSK2399872A) is an effective and specific RIP3 kinase inhibitor.
Formula:
C19H18ClN3O2S2
Purity:
99%
Color and Shape:
Solid
Molecular weight:
419.94
Ref: TM-T4074L
| 1mg | 37.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
