NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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GGTI 2147
CAS:191102-87-1
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
Formula:
C28H30N4O3
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
470.56
Ref: TM-T25450
| 1mg | 495.00 € | ||
| 5mg | 1,111.00 € | ||
| 10mg | 1,454.00 € | ||
| 25mg | 1,882.00 € | ||
| 50mg | 2,262.00 € | ||
| 100mg | 2,945.00 € |
Estimated delivery in United States, on Wednesday 2 Jul 2025
ACHP Hydrochloride
CAS:406209-26-5
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an …
Formula:
C21H25ClN4O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
400.9
Ref: TM-T10237
| 1mg | 66.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 375.00 € | ||
| 50mg | 540.00 € | ||
| 100mg | 777.00 € | ||
| 500mg | 1,549.00 € | ||
| 1mL*10mM (DMSO) | 159.00 € |
Estimated delivery in United States, on Wednesday 2 Jul 2025
Demethyleneberberine chloride
CAS:16705-03-6
Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by …
Formula:
C19H18ClNO4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
359.8
Ref: TM-T78095
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 2 Jul 2025
IR-Crizotinib
CAS:2387927-74-2
IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) …
Formula:
C53H57Cl2FIN7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1024.88
Ref: TM-T82049
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 2 Jul 2025
Ginsenoside Rk1
CAS:494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formula:
C42H70O12
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T4S1499
| 5mg | 93.00 € |
Estimated delivery in United States, on Wednesday 2 Jul 2025
GSK840
CAS:2361146-30-5
GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the …
Formula:
C21H23N3O3
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
365.43
Ref: TM-T11501
| 1mg | 38.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 284.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Wednesday 2 Jul 2025
PROTAC IRAK4 degrader-8
CAS:2911615-06-8
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 …
Formula:
C43H50ClF2N11O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
874.38
Ref: TM-T79097
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 2 Jul 2025
NLRP3-IN-9
CAS:88039-46-7
NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.
Formula:
C12H13ClO3
Purity:
98.51%
Color and Shape:
Solid
Molecular weight:
240.68
Ref: TM-T28178
| 1mg | 42.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 645.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 2 Jul 2025
HOIPIN-8 sodium
CAS:2519537-70-1
HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.
Formula:
C23H15F2N4NaO3
Purity:
97.34%
Color and Shape:
Liquid
Molecular weight:
456.38
Ref: TM-T62826
| 1mg | 115.00 € | ||
| 5mg | 274.00 € | ||
| 10mg | 472.00 € | ||
| 25mg | 905.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 2,242.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
Ocadusertib
CAS:2382811-41-6
Ocadusertib is an effective inhibitor of the serine/threonine kinase receptor-interacting protein kinase 1 (RIPK1).
Formula:
C25H25N5O4
Color and Shape:
Solid
Molecular weight:
459.50
Ref: TM-T201183
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
TBK1/IKKε-IN-1
CAS:2058264-32-5
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
Formula:
C28H26N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
498.53
Ref: TM-T13097
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
BMS-066
CAS:914946-88-6
BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.
Formula:
C19H21N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
379.42
Ref: TM-T14669
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
Sabialimon P
CAS:2267333-96-8
Sabialimon P (compound 16), with an IC50 of 18.12 μM, functions as a NO release …
Formula:
C31H50O4
Color and Shape:
Solid
Molecular weight:
486.73
Ref: TM-T200238
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
GTCpFE
CAS:1588866-45-8
GTCpFE, a compound synthesized from Dimethyl fumarate (DMF) and Aspirin (ASA), inhibits IKKα/β in the …
Formula:
C22H20O8
Color and Shape:
Solid
Molecular weight:
412.39
Ref: TM-T200141
| 25mg | 1,539.00 € | ||
| 50mg | 1,941.00 € | ||
| 100mg | 2,451.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
Antiproliferative agent-22
CAS:1374305-45-9
Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 …
Formula:
C17H13N3O3
Purity:
99.20% - 99.30%
Color and Shape:
Solid
Molecular weight:
307.3
Ref: TM-T85699
| 1mg | 201.00 € | ||
| 5mg | 497.00 € | ||
| 10mg | 701.00 € | ||
| 25mg | 1,094.00 € | ||
| 50mg | 1,508.00 € | ||
| 100mg | 1,931.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
SBI-0640726
CAS:1321827-45-5
SBI-0640726, an eIF4G1 inhibitor, exhibits antiproliferative activity against melanoma. It disrupts the eIF4F translation initiation …
Formula:
C23H15ClN2O2
Color and Shape:
Solid
Molecular weight:
386.83
Ref: TM-T89836
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
NIK-IN-2
CAS:1202763-91-4
NIK-IN-2 (compound 1) is an effective inhibitor of NF-κB inducing kinase (NIK), exhibiting a pIC50 …
Formula:
C20H22N4O3
Color and Shape:
Liquid
Molecular weight:
366.41
Ref: TM-T201462
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
TNFα activity modulator 3
CAS:2248726-53-4
TNFα Activity Modulator 3 (example 6) is a molecule that regulates TNF activity by inhibiting …
Formula:
C27H24F2N6O2
Color and Shape:
Solid
Molecular weight:
502.52
Ref: TM-T89932
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
4-Octylphenol
CAS:1806-26-4
4-Octylphenol is an endocrine disruptor with gender-specific effects on male germ cells, significantly reducing the …
Formula:
C14H22O
Color and Shape:
Liquid
Molecular weight:
206.32
Ref: TM-T201798
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 30 Jul 2025
UBS109
CAS:1258513-40-4
UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast …
Formula:
C18H17N3O
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
291.35
Ref: TM-T88314
| 2mg | 38.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 254.00 € | ||
| 100mg | 389.00 € | ||
| 200mg | 566.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 30 Jul 2025
