NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Oditrasertib
CAS:2252271-93-3
Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in …
Formula:
C14H15F2N3O2
Purity:
98.65% - 99.65%
Color and Shape:
Liquid
Molecular weight:
295.28
Ref: TM-T69726
| 1mg | 134.00 € | ||
| 5mg | 323.00 € | ||
| 10mg | 524.00 € | ||
| 25mg | 1,043.00 € | ||
| 50mg | 1,657.00 € | ||
| 100mg | 2,681.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Supercinnamaldehyde
CAS:70351-51-8
Supercinnamaldehyde is a potent activator of transient receptor potential ankyrin 1 (TRPA1), exhibiting an EC50 …
Formula:
C12H11NO2
Purity:
98.89%
Color and Shape:
Liquid
Molecular weight:
201.22
Ref: TM-T78082
| 1mg | 47.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 446.00 € | ||
| 100mg | 733.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Dimethoxycurcumin
CAS:160096-59-3
Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.
Formula:
C23H24O6
Purity:
96.05%
Color and Shape:
Solid
Molecular weight:
396.43
Ref: TM-T19853
| 5mg | 50.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 339.00 € | ||
| 200mg | 483.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
GSK840
CAS:2361146-30-5
GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the …
Formula:
C21H23N3O3
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
365.43
Ref: TM-T11501
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Demethyleneberberine chloride
CAS:16705-03-6
Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by …
Formula:
C19H18ClNO4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
359.8
Ref: TM-T78095
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Feb 2025
IRAK4-IN-28
CAS:2952532-92-0
IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a …
Formula:
C27H31N9O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
529.59
Ref: TM-T79337
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
IMD-vanillin
CAS:2928463-38-9
IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.
Formula:
C37H45N7O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
651.8
Ref: TM-T72926
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Antiproliferative agent-22
CAS:1374305-45-9
Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 …
Formula:
C17H13N3O3
Purity:
99.20% - 99.30%
Color and Shape:
Liquid
Molecular weight:
307.3
Ref: TM-T85699
| 1mg | 197.00 € | ||
| 5mg | 486.00 € | ||
| 10mg | 682.00 € | ||
| 25mg | 1,064.00 € | ||
| 50mg | 1,468.00 € | ||
| 100mg | 1,879.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
BMS-066
CAS:914946-88-6
BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.
Formula:
C19H21N7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
379.42
Ref: TM-T14669
| 25mg | 2,245.00 € | ||
| 50mg | 2,972.00 € | ||
| 100mg | 4,019.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
HOIPIN-8 sodium
CAS:2519537-70-1
HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.
Formula:
C23H15F2N4NaO3
Color and Shape:
Liquid
Molecular weight:
456.38
Ref: TM-T62826
| 1mg | 113.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 461.00 € | ||
| 25mg | 884.00 € | ||
| 50mg | 1,383.00 € | ||
| 100mg | 2,190.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
TBK1/IKKε-IN-1
CAS:2058264-32-5
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
Formula:
C28H26N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
498.53
Ref: TM-T13097
| 25mg | 2,238.00 € | ||
| 50mg | 2,974.00 € | ||
| 100mg | 4,021.00 € |
Estimated delivery in United States, on Monday 10 Mar 2025
GTCpFE
CAS:1588866-45-8
GTCpFE, a compound synthesized from Dimethyl fumarate (DMF) and Aspirin (ASA), inhibits IKKα/β in the …
Formula:
C22H20O8
Color and Shape:
Liquid
Molecular weight:
412.39
Ref: TM-T200141
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
SBI-0640726
CAS:1321827-45-5
SBI-0640726, an eIF4G1 inhibitor, exhibits antiproliferative activity against melanoma. It disrupts the eIF4F translation initiation …
Formula:
C23H15ClN2O2
Color and Shape:
Liquid
Molecular weight:
386.83
Ref: TM-T89836
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
Sabialimon P
CAS:2267333-96-8
Sabialimon P (compound 16), with an IC50 of 18.12 μM, functions as a NO release …
Formula:
C31H50O4
Color and Shape:
Liquid
Molecular weight:
486.73
Ref: TM-T200238
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
TNFα activity modulator 3
CAS:2248726-53-4
TNFα Activity Modulator 3 (example 6) is a molecule that regulates TNF activity by inhibiting …
Formula:
C27H24F2N6O2
Color and Shape:
Liquid
Molecular weight:
502.52
Ref: TM-T89932
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Mar 2025
Inulicin
CAS:33627-41-7
Inulicin (1-O-Acetylbritannilactone), an active compound isolated from Inula Britannica L, inhibits VEGF-mediated activation of Src …
Formula:
C17H24O5
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
308.37
Ref: TM-TQ0169
| 1mg | Discontinued | Request information | |
| 1ml | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information |
RI-962
CAS:2763831-53-2
RI-962 inhibits RIPK1 with 35.0 nM IC50, used in researching nervous and inflammatory diseases.
Formula:
C28H28N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
480.56
Ref: TM-T73493
| 5mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information |
