NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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BMS-345541 hydrochloride
CAS:547757-23-3
BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM …
Formula:
C14H18ClN5
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
291.78
Ref: TM-T8542
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 220.00 € | ||
| 50mg | 368.00 € | ||
| 100mg | 551.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
IKK 16
CAS:873225-46-8
IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK …
Formula:
C28H29N5OS
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
483.63
Ref: TM-T6176
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 398.00 € | ||
| 100mg | 593.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
GSK2983559 active metabolite
CAS:1423186-80-4
GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
Formula:
C21H22N4O4S2
Purity:
97.07% - 98.48%
Color and Shape:
Solid
Molecular weight:
458.55
Ref: TM-T5401
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 270.00 € | ||
| 50mg | 503.00 € | ||
| 100mg | 725.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
NF-κΒ activator 2
CAS:2375281-44-8
NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an …
Formula:
C16H11FN2O3
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
298.27
Ref: TM-T39924
| 1mg | 90.00 € | ||
| 2mg | 131.00 € | ||
| 5mg | 218.00 € | ||
| 10mg | 324.00 € | ||
| 25mg | 520.00 € | ||
| 50mg | 704.00 € | ||
| 100mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 240.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Eurycomalactone
CAS:23062-24-0
Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, …
Formula:
C19H24O6
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
348.39
Ref: TM-TN1637
| 1mg | 142.00 € | ||
| 5mg | 331.00 € | ||
| 10mg | 490.00 € | ||
| 25mg | 780.00 € | ||
| 50mg | 1,051.00 € | ||
| 1mL*10mM (DMSO) | 261.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
JSH-23
CAS:749886-87-1
JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 …
Formula:
C16H20N2
Purity:
98.03% - 99.67%
Color and Shape:
Solid
Molecular weight:
240.34
Ref: TM-T1930
| 1mg | 42.00 € | ||
| 2mg | 61.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 189.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 421.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
GS143
CAS:916232-21-8
GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.
Formula:
C28H19FN2O4
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
466.46
Ref: TM-T25465
| 2mg | 37.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 528.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Isodeoxyelephantopin
CAS:38927-54-7
Isodeoxyelephantopin can inhibit the growth of various tumor cells.
Formula:
C19H20O6
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
344.36
Ref: TM-TN1141
| 1mg | 253.00 € | ||
| 5mg | 629.00 € | ||
| 10mg | 893.00 € | ||
| 25mg | 1,318.00 € | ||
| 50mg | 1,756.00 € | ||
| 1mL*10mM (DMSO) | 636.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
IKKγ NBD Inhibitory Peptide acetate
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to …
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
N/A
Ref: TM-TP1615L
| 1mg | 128.00 € | ||
| 2mg | 170.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 870.00 € | ||
| 100mg | 1,179.00 € | ||
| 500mg | 2,377.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Vamorolone
CAS:13209-41-1
Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and …
Formula:
C22H28O4
Purity:
98.04%
Color and Shape:
Solid
Molecular weight:
356.46
Ref: TM-T17217
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 435.00 € | ||
| 200mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Robinin
CAS:301-19-9
Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP …
Formula:
C33H40O19
Purity:
98% - 98.91%
Color and Shape:
Solid
Molecular weight:
740.66
Ref: TM-T2S0265
| 1mg | 74.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 13 Jan 2025
Engeletin
CAS:572-31-6
1.
Formula:
C21H22O10
Purity:
99.72% - 99.99%
Color and Shape:
Solid
Molecular weight:
434.39
Ref: TM-T6S0840
| 5mg | 48.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 393.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Polygalasaponin F
CAS:882664-74-6
Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.
Formula:
C53H86O23
Purity:
98% - 99.83%
Color and Shape:
Solid
Molecular weight:
1091.24
Ref: TM-T3826
| 20mg | 96.00 € | ||
| 1mL*10mM (DMSO) | 118.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Embelin
CAS:550-24-3
Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked …
Formula:
C17H26O4
Purity:
97.07% - 99.88%
Color and Shape:
Solid
Molecular weight:
294.39
Ref: TM-T6485
| 10mg | 54.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 154.00 € | ||
| 100mg | 292.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Triptolide
CAS:38748-32-2
Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor …
Formula:
C20H24O6
Purity:
97.19% - 99.83%
Color and Shape:
White To Off-White Solid
Molecular weight:
360.4
Ref: TM-T2179
| 1mg | 44.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Barlerin
CAS:57420-46-9
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose …
Formula:
C19H28O12
Purity:
99.83% - ≥95%
Color and Shape:
Solid
Molecular weight:
448.42
Ref: TM-T5S1632
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 239.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 524.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
TBK1/IKKε-IN-5
CAS:1893397-65-3
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).
Formula:
C28H31N7O3
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
513.59
Ref: TM-T7951
| 1mg | 90.00 € | ||
| 5mg | 186.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 437.00 € | ||
| 50mg | 598.00 € | ||
| 100mg | 851.00 € | ||
| 200mg | 1,144.00 € | ||
| 1mL*10mM (DMSO) | 227.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Mollugin
CAS:55481-88-4
Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and …
Formula:
C17H16O4
Purity:
98.31% - ≥95%
Color and Shape:
Solid
Molecular weight:
284.31
Ref: TM-T3673
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 276.00 € | ||
| 500mg | 681.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Tyrosol
CAS:501-94-0
Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as …
Formula:
C8H10O2
Purity:
100% - 99.69%
Color and Shape:
Solid
Molecular weight:
138.16
Ref: TM-T2861
| 500mg | 79.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
PI-1840
CAS:1401223-22-0
PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on …
Formula:
C22H26N4O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
394.47
Ref: TM-T6941
| 5mg | 37.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 215.00 € | ||
| 100mg | 321.00 € | ||
| 200mg | 459.00 € | ||
| 1mL*10mM (DMSO) | 37.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
