NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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E3330
CAS:136164-66-4
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
Formula:
C21H30O6
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
378.46
Ref: TM-T6823
| 1mg | 50.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 494.00 € | ||
| 100mg | 716.00 € | ||
| 200mg | 1,004.00 € | ||
| 500mg | 1,476.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
DHMEQ racemate
CAS:287194-38-1
DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.
Formula:
C13H11NO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
261.23
Ref: TM-T11018
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Gue1654
CAS:397290-30-1
Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of …
Formula:
C23H17N3OS3
Purity:
98.02% - 98.31%
Color and Shape:
Solid
Molecular weight:
447.6
Ref: TM-T27502
| 1mg | 79.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 239.00 € | ||
| 25mg | 553.00 € | ||
| 50mg | 981.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
NF-κB-IN-11
CAS:2768833-35-6
NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and …
Formula:
C19H18O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
326.34
Ref: TM-T79671
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
IMD-catechol
CAS:2928463-39-0
IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.
Formula:
C31H34N6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
538.64
Ref: TM-T72927
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
SP-100030
CAS:154563-54-9
SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.
Formula:
C14H5ClF9N3O
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
437.65
Ref: TM-T24816
| 1mg | 36.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 239.00 € | ||
| 50mg | 371.00 € | ||
| 100mg | 534.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
GSK319347A
CAS:862812-98-4
GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be …
Formula:
C22H19N3O5S2
Purity:
98.42%
Color and Shape:
Solid
Molecular weight:
469.53
Ref: TM-T15558
| 1mg | 74.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 526.00 € | ||
| 50mg | 893.00 € | ||
| 100mg | 1,204.00 € | ||
| 1mL*10mM (DMSO) | 338.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Zharp2-1
CAS:2772600-18-5
Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be …
Formula:
C19H18N3O2PS
Purity:
99.41%
Color and Shape:
Liquid
Molecular weight:
383.4
Ref: TM-T79600
| 5mg | 67.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 479.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Lobeglitazone Sulfate
CAS:763108-62-9
Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used …
Formula:
C24H26N4O9S2
Purity:
98.69%
Color and Shape:
Solid
Molecular weight:
578.61
Ref: TM-T27841
| 1mg | 109.00 € | ||
| 5mg | 258.00 € | ||
| 10mg | 414.00 € | ||
| 25mg | 660.00 € | ||
| 50mg | 983.00 € | ||
| 100mg | 1,437.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Zabedosertib
CAS:1931994-81-8
Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.
Formula:
C20H21F3N4O4S
Purity:
98.48%
Color and Shape:
Liquid
Molecular weight:
470.47
Ref: TM-T37076
| 1mg | 42.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 442.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
SZM679
SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, …
Formula:
C27H18F5N3O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
591.51
Ref: TM-T73511
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
AP-1/NF-κB activation inhibitor 1
CAS:188936-12-1
AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation …
Formula:
C13H11F3N4O4
Purity:
100% - 99.74%
Color and Shape:
Liquid
Molecular weight:
344.25
Ref: TM-T9656
| 1mg | 72.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 215.00 € | ||
| 25mg | 351.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 724.00 € | ||
| 500mg | 1,470.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
IMD-biphenylA
CAS:2928463-40-3
IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties …
Formula:
C35H33N5O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
555.67
Ref: TM-T72869
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Selnoflast
CAS:2260969-36-4
Selnoflast (RO-7486967) is an orally active, potent and selective NLRP3 inhibitor for the study of …
Formula:
C20H29N3O3S
Purity:
100% - 99.82%
Color and Shape:
Liquid
Molecular weight:
391.53
Ref: TM-T61786
| 1mg | 128.00 € | ||
| 2mg | 180.00 € | ||
| 5mg | 301.00 € | ||
| 10mg | 502.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,548.00 € | ||
| 100mg | 2,546.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
IMD-biphenylB
CAS:2928463-41-4
IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.
Formula:
C35H33N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
571.67
Ref: TM-T72870
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
CID-2858522
CAS:758679-97-9
CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).
Formula:
C28H39N3O3
Purity:
96.11%
Color and Shape:
Solid
Molecular weight:
465.63
Ref: TM-TQ0305
| 1mg | 41.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 219.00 € | ||
| 50mg | 325.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
NFATc1-IN-1
CAS:1912422-56-0
NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.
Formula:
C13H8F2INO2
Purity:
99.64%
Color and Shape:
Liquid
Molecular weight:
375.11
Ref: TM-T61531
| 5mg | 51.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 346.00 € | ||
| 500mg | 807.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
RIP1 kinase inhibitor 5
CAS:2428422-17-5
RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by …
Formula:
C13H17F2NO2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
257.28
Ref: TM-T79042
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
Penehyclidine hydrochloride
CAS:151937-76-7
Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.
Formula:
C20H30ClNO2
Purity:
99.7%
Color and Shape:
Liquid
Molecular weight:
351.91
Ref: TM-T61233
| 1mg | 137.00 € | ||
| 5mg | 331.00 € | ||
| 10mg | 489.00 € | ||
| 25mg | 787.00 € | ||
| 50mg | 1,050.00 € | ||
| 1mL*10mM (DMSO) | 338.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
NLRP3-IN-13
CAS:1704638-35-6
NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study …
Formula:
C19H15N3O3S
Purity:
98.82%
Color and Shape:
Liquid
Molecular weight:
365.41
Ref: TM-T73018
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 643.00 € | ||
| 100mg | 1,018.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
