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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 445 products of "NF-κB"

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  • Guaiacol
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    Guaiacol

    CAS:
    <p>Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.</p>
    Formula:C7H8O2
    Purity:99.95%
    Color and Shape:Colourless To Pale Yellow Solid Crystalline
    Molecular weight:124.14

    Ref: TM-T1301

  • GSK3145095
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    GSK3145095

    CAS:
    <p>GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.</p>
    Formula:C20H17F2N5O2
    Purity:99.50%
    Color and Shape:Solid
    Molecular weight:397.38

    Ref: TM-T15437

  • Ergolide
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    Ergolide

    CAS:
    <p>Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.</p>
    Formula:C17H22O5
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:306.35

    Ref: TM-T13686

  • DRI-C21045
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    DRI-C21045

    CAS:
    <p>Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).</p>
    Formula:C32H24N2O7S
    Purity:97.20%
    Color and Shape:Solid
    Molecular weight:580.61

    Ref: TM-T11096

  • Sulindac
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    Sulindac

    CAS:
    <p>Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.</p>
    Formula:C20H17FO3S
    Purity:99.09% - 99.15%
    Color and Shape:Yellow Solid
    Molecular weight:356.41

    Ref: TM-T0459

  • 4-Hydroxychalcone
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    4-Hydroxychalcone

    CAS:
    <p>4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.</p>
    Formula:C15H12O2
    Purity:99.75%
    Color and Shape:Yellow Powder
    Molecular weight:224.25

    Ref: TM-T3005

  • Indacaterol maleate
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    Indacaterol maleate

    CAS:
    <p>Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.</p>
    Formula:C28H32N2O7
    Purity:99.03% - 99.67%
    Color and Shape:Solid
    Molecular weight:508.56

    Ref: TM-T1239

  • Dihydroartemisinin
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    Dihydroartemisinin

    CAS:
    <p>Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!</p>
    Formula:C15H24O5
    Purity:98% - 99.41%
    Color and Shape:White Solid
    Molecular weight:284.35

    Ref: TM-T0607

  • Nimbolide
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    Nimbolide

    CAS:
    <p>Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.</p>
    Formula:C27H30O7
    Purity:95.84% - 99.4%
    Color and Shape:Solid
    Molecular weight:466.52

    Ref: TM-T16324

  • TBK1/IKKε-IN-2
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    TBK1/IKKε-IN-2

    CAS:
    <p>TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.</p>
    Formula:C26H27N5O3
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:457.52

    Ref: TM-T15559

  • Sulfasalazine
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    Sulfasalazine

    CAS:
    <p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>
    Formula:C18H14N4O5S
    Purity:98.00% - 99.28%
    Color and Shape:Minute Brownish-Yellow Crystals
    Molecular weight:398.39

    Ref: TM-T0907

  • Theophylline
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    Theophylline

    CAS:
    <p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>
    Formula:C7H8N4O2
    Purity:99.65% - 99.98%
    Color and Shape:White Solid Powder
    Molecular weight:180.16

    Ref: TM-T1083

  • Sodium salicylate
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    Sodium salicylate

    CAS:
    <p>Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.</p>
    Formula:C7H5NaO3
    Purity:99.36% - 99.92%
    Color and Shape:White Solid Amorphous
    Molecular weight:160.11

    Ref: TM-T0335

  • CDDO-dhTFEA
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    CDDO-dhTFEA

    CAS:
    <p>CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.</p>
    Formula:C33H45F3N2O3
    Purity:95.61% - 99.59%
    Color and Shape:Solid
    Molecular weight:574.72

    Ref: TM-T13604

  • Sinomenine hydrochloride
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    Sinomenine hydrochloride

    CAS:
    <p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>
    Formula:C19H24ClNO4
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:365.851

    Ref: TM-T2921

  • Lidocaine Hydrochloride hydrate
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    Lidocaine Hydrochloride hydrate

    CAS:
    <p>Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.</p>
    Formula:C14H22N2O·HCl·H2O
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:288.82

    Ref: TM-T1144L

  • Theophylline monohydrate
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    Theophylline monohydrate

    CAS:
    <p>Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium</p>
    Formula:C7H8N4O2·H2O
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:198.18

    Ref: TM-T1083L

  • Baicalin
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    Baicalin

    CAS:
    <p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>
    Formula:C21H18O11
    Purity:90.08% - 99.32%
    Color and Shape:Yellow Powder
    Molecular weight:446.36

    Ref: TM-T2775

  • DMAPT
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    DMAPT

    CAS:
    <p>DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in acute myeloid leukemia cells.</p>
    Formula:C17H27NO3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:293.4

    Ref: TM-T11060

  • AZ1495
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    AZ1495

    CAS:
    <p>AZ1495: oral IRAK4 inhibitor (IC50: 5 nM), IRAK1 (23 nM), treats MYD88L265P DLBCL.</p>
    Formula:C21H31N5O2
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:385.5

    Ref: TM-T14367