NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Guaiacol
CAS:90-05-1
Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown …
Formula:
C7H8O2
Purity:
99.83%
Color and Shape:
Colourless To Pale Yellow Solid Crystalline
Molecular weight:
124.14
Ref: TM-T1301
| 10g | 39.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
α-Lipoic Acid
CAS:1077-28-7
α-Lipoic Acid, a sulfur-containing octanoic acid derivative, is biosynthesized from linoleic acid and used in …
Formula:
C8H14O2S2
Purity:
98.39%
Color and Shape:
Forms Yellowish Flakes Light Yellow To Yellow Powder
Molecular weight:
206.33
Ref: TM-T0200
| 1g | 34.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Sulindac
CAS:38194-50-2
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.
Formula:
C20H17FO3S
Purity:
99.32% - 99.49%
Color and Shape:
Yellow Solid
Molecular weight:
356.41
Ref: TM-T0459
| 50mg | 52.00 € | ||
| 100mg | 56.00 € | ||
| 200mg | 76.00 € | ||
| 500mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
TBK1/IKKε-IN-2
CAS:1292310-49-6
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
Formula:
C26H27N5O3
Purity:
98.89%
Color and Shape:
Solid
Molecular weight:
457.52
Ref: TM-T15559
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 476.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 827.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Molsidomine
CAS:25717-80-0
Molsidomine, an oral vasodilator, turns into linsidomine in the liver, releasing NO for prolonged effects.
Formula:
C9H14N4O4
Purity:
100% - 99.96%
Color and Shape:
Colorless Or White Crystalline Powder
Molecular weight:
242.23
Ref: TM-T0109
| 200mg | 35.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Aspirin
CAS:50-78-2
Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective …
Formula:
C9H8O4
Purity:
100%
Color and Shape:
White Solid Crystalline
Molecular weight:
180.16
Ref: TM-T0005
| 1g | 57.00 € | ||
| 5g | 94.00 € | ||
| 200mg | 37.00 € | ||
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
NIK SMI1
CAS:1660114-31-7
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits …
Formula:
C20H19N3O4
Purity:
99.04% - 99.99%
Color and Shape:
Solid
Molecular weight:
365.38
Ref: TM-T16290
| 1mg | 158.00 € | ||
| 5mg | 384.00 € | ||
| 10mg | 578.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,243.00 € | ||
| 100mg | 1,663.00 € | ||
| 1mL*10mM (DMSO) | 430.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
DCZ0415
CAS:2242470-43-3
DCZ0415: Potent TRIP13 inhibitor; combats myeloma in vitro, in vivo, and in drug-resistant patients; hinders …
Formula:
C23H20N2O2
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
356.42
Ref: TM-T10981
| 1mg | 52.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 576.00 € | ||
| 100mg | 854.00 € | ||
| 1mL*10mM (DMSO) | 125.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
5-Aminosalicylic Acid
CAS:89-57-6
5-ASA, an anti-inflammatory salicylate, treats inflammatory bowel disease, active part of sulphalazine.
Formula:
C7H7NO3
Purity:
97.88% - 99.98%
Color and Shape:
Purplish-Tan Solid Powder
Molecular weight:
153.14
Ref: TM-T0646
| 500mg | 49.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Sodium salicylate
CAS:54-21-7
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and …
Formula:
C7H5NaO3
Purity:
100% - 99.98%
Color and Shape:
White Solid Amorphous
Molecular weight:
160.11
Ref: TM-T0335
| 500mg | 49.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
IRAK4-IN-4
CAS:1850276-58-2
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is …
Formula:
C22H16N2O2
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
340.37
Ref: TM-T11673
| 1mg | 62.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 364.00 € | ||
| 50mg | 546.00 € | ||
| 100mg | 785.00 € | ||
| 200mg | 1,052.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
DRI-C21045
CAS:2101765-81-3
Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).
Formula:
C32H24N2O7S
Purity:
98.10%
Color and Shape:
Solid
Molecular weight:
580.61
Ref: TM-T11096
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 230.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 487.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Urolithin B
CAS:1139-83-9
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in …
Formula:
C13H8O3
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
212.2
Ref: TM-T13265
| 10mg | 46.00 € | ||
| 25mg | 77.00 € | ||
| 50mg | 120.00 € | ||
| 100mg | 187.00 € | ||
| 500mg | 464.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
4-Aminosalicylic acid
CAS:65-49-6
4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.
Formula:
C7H7NO3
Purity:
97.07%
Color and Shape:
Minute Crystals From Alc Solid
Molecular weight:
153.14
Ref: TM-T1296
| 1g | 34.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
RIPK1-IN-7
CAS:2300982-44-7
RIPK1-IN-7: Strong, selective RIPK1 inhibitor (Kd=4 nM, IC50=11 nM) with great antimetastasis effects in B16 …
Formula:
C25H22F3N5O2
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
481.47
Ref: TM-T12731
| 1mg | 89.00 € | ||
| 5mg | 209.00 € | ||
| 10mg | 318.00 € | ||
| 25mg | 493.00 € | ||
| 50mg | 682.00 € | ||
| 100mg | 909.00 € | ||
| 1mL*10mM (DMSO) | 225.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Baicalin
CAS:21967-41-9
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, …
Formula:
C21H18O11
Purity:
90.08% - 99.25%
Color and Shape:
Yellow Powder
Molecular weight:
446.36
Ref: TM-T2775
| 50mg | 41.00 € | ||
| 100mg | 50.00 € | ||
| 500mg | 64.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Ergolide
CAS:54999-07-4
Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.
Formula:
C17H22O5
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
306.35
Ref: TM-T13686
| 1mg | 73.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 238.00 € | ||
| 25mg | 387.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 721.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Sinomenine hydrochloride
CAS:6080-33-7
Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.
Formula:
C19H24ClNO4
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
365.851
Ref: TM-T2921
| 50mg | 44.00 € | ||
| 100mg | 56.00 € | ||
| 200mg | 72.00 € | ||
| 500mg | 103.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
GSK3145095
CAS:1622849-43-7
GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential …
Formula:
C20H17F2N5O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
397.38
Ref: TM-T15437
| 1mg | 94.00 € | ||
| 5mg | 241.00 € | ||
| 10mg | 337.00 € | ||
| 25mg | 541.00 € | ||
| 50mg | 711.00 € | ||
| 100mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 238.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Erdosteine
CAS:84611-23-4
Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects …
Formula:
C8H11NO4S2
Purity:
99.43% - 99.63%
Color and Shape:
White Or Almost White Crystalline Powder
Molecular weight:
249.31
Ref: TM-T1229
| 1g | 95.00 € | ||
| 100mg | 36.00 € | ||
| 500mg | 72.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
