NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 406 products of "NF-κB"
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Guaiacol
CAS:Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.
Formula:C7H8O2Purity:99.95%Color and Shape:Colourless To Pale Yellow Solid CrystallineMolecular weight:124.14SN50 acetate (213546-53-3 free base)
SN50 acetate is a cell permeable inhibitor of NF-κB translocation.Formula:C131H234N36O31SPurity:99.86%Color and Shape:SolidMolecular weight:2841.55Sodium salicylate
CAS:Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Formula:C7H5NaO3Purity:99.36% - 99.92%Color and Shape:White Solid AmorphousMolecular weight:160.11DRI-C21045
CAS:Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).Formula:C32H24N2O7SPurity:97.20%Color and Shape:SolidMolecular weight:580.61Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Formula:C20H17FO3SPurity:99.09% - 99.15%Color and Shape:Yellow SolidMolecular weight:356.414-Hydroxychalcone
CAS:4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.Formula:C15H12O2Purity:99.75%Color and Shape:Yellow PowderMolecular weight:224.25Indacaterol maleate
CAS:Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Formula:C28H32N2O7Purity:99.03% - 99.67%Color and Shape:SolidMolecular weight:508.56Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!Formula:C15H24O5Purity:98% - 99.41%Color and Shape:White SolidMolecular weight:284.35Nimbolide
CAS:Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.Formula:C27H30O7Purity:95.84% - 99.4%Color and Shape:SolidMolecular weight:466.52Ref: TM-T16324
1mg67.00€5mg167.00€10mg289.00€25mg595.00€50mg820.00€100mg1,108.00€200mg1,440.00€1mL*10mM (DMSO)180.00€TBK1/IKKε-IN-2
CAS:TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.Formula:C26H27N5O3Purity:98.89%Color and Shape:SolidMolecular weight:457.52Ref: TM-T15559
1mg87.00€5mg178.00€10mg289.00€25mg462.00€50mg625.00€100mg802.00€1mL*10mM (DMSO)178.00€Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurity:98.00% - 99.28%Color and Shape:Minute Brownish-Yellow CrystalsMolecular weight:398.39Ergolide
CAS:Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.Formula:C17H22O5Purity:99.64%Color and Shape:SolidMolecular weight:306.35Ref: TM-T13686
1mg71.00€5mg139.00€10mg230.00€25mg374.00€50mg520.00€100mg697.00€1mL*10mM (DMSO)166.00€CDDO-dhTFEA
CAS:CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.Formula:C33H45F3N2O3Purity:95.61% - 99.59%Color and Shape:SolidMolecular weight:574.72Ref: TM-T13604
1mg70.00€2mg92.00€5mg153.00€10mg255.00€25mg512.00€50mg738.00€100mg1,035.00€500mg2,062.00€1mL*10mM (DMSO)187.00€Theophylline
CAS:Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFormula:C7H8N4O2Purity:99.65% - 99.98%Color and Shape:White Solid PowderMolecular weight:180.16Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Formula:C19H24ClNO4Purity:99.43%Color and Shape:SolidMolecular weight:365.85Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formula:C14H22N2O·HCl·H2OPurity:99.95%Color and Shape:SolidMolecular weight:288.82Theophylline monohydrate
CAS:Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calciumFormula:C7H8N4O2·H2OPurity:99.78%Color and Shape:SolidMolecular weight:198.18Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFormula:C21H18O11Purity:90.08% - 99.32%Color and Shape:Yellow PowderMolecular weight:446.36Ref: TM-T2775
1g80.00€2g102.00€5g152.00€50mg34.00€100mg49.00€200mg49.00€500mg55.00€1mL*10mM (DMSO)50.00€DMAPT
CAS:DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in acute myeloid leukemia cells.Formula:C17H27NO3Purity:99.91%Color and Shape:SolidMolecular weight:293.4IMD-0560
CAS:IMD-0560 is a novel inhibitor of IκB kinase β.Formula:C15H8BrF6NO2Purity:99.51%Color and Shape:SolidMolecular weight:428.12
