CCR
C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.
Found 165 products for "CCR".
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BX471
CAS:BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.Formula:C21H24ClFN4O3Purity:98% - 99.98%Color and Shape:SolidMolecular weight:434.89R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Formula:C21H27NO4Purity:99.03% - 99.16%Color and Shape:Yellow SolidMolecular weight:357.4434Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Formula:C28H38F3N5O2Color and Shape:SolidMolecular weight:533.63RS102895
CAS:RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.Formula:C21H21F3N2O2Purity:97.64% - 99.80%Color and Shape:SolidMolecular weight:390.3988Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Formula:C19H20N2O3Purity:98.35% - 98.55%Color and Shape:SolidMolecular weight:324.3737PF-4136309
CAS:PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.Formula:C29H31F3N6O3Purity:98.85% - 99.47%Color and Shape:SolidMolecular weight:568.59Vicriviroc maleate
CAS:Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.Formula:C32H42F3N5O6Purity:98.16% - 98.37%Color and Shape:White SolidMolecular weight:649.701RE-640
CAS:NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.Formula:C20H16Cl2N4Purity:99.60% - 99.87%Color and Shape:White SolidMolecular weight:383.274RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purity:98.64% - 99.68%Color and Shape:SolidMolecular weight:417.5Cenicriviroc
CAS:Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.Formula:C41H52N4O4SPurity:97.87%Color and Shape:Yellow SolidMolecular weight:696.941SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Formula:C18H18N2O5Purity:99.59%Color and Shape:White SolidMolecular weight:342.35Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Formula:C22H21ClN2NaO4SColor and Shape:SolidMolecular weight:467.92C-021
CAS:C 021 dihydrochloride is a potent CCR4 antagonist.Formula:C27H41N5O2Purity:99.74% - 99.90%Color and Shape:White SolidMolecular weight:467.65AZD2098
CAS:AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.Formula:C11H9Cl2N3O3SPurity:99.75% - 99.94%Color and Shape:SolidMolecular weight:334.178INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Formula:C26H31F3N4O4Purity:97.81% - 99.46%Color and Shape:SolidMolecular weight:520.5439Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5)
Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) is a monoclonal antibody targeting mouse/human/rat CCL2/MCP-1, capable of blocking the CCL2 signalling pathway.Purity:95% - 99%Color and Shape:Transparent LiquidMolecular weight:~150 kDaCarlumab
CAS:Carlumab is a high-affinity human monoclonal antibody that targets CCL2, suppressing the recruitment of monocytes/macrophages in the tumour microenvironment.Purity:95%Color and Shape:Transparent LiquidMolecular weight:144.87 kDa (Predicted)Tivumecirnon
CAS:Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumourFormula:C24H27Cl2F3N6OPurity:99.88%Color and Shape:SolidMolecular weight:543.41Lanerkitug
Lanerkitug (BAY3375968) is a fully humanized anti-CCR8 IgG1 mAb that depletes CCR8+ Tregs via ADCC and ADCP, with potential in solid tumor therapy.Purity:95%Color and Shape:Odour LiquidMolecular weight:~148 kDaCafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour Liquid
