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CCR

CCR

C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.

Found 136 products of "CCR"

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  • RS 504393
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    RS 504393

    CAS:
    <p>RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and &gt; 100 μM for human recombinant CCR2 and CCR1).</p>
    Formula:C25H27N3O3
    Purity:98.64% - 99.62%
    Color and Shape:Solid
    Molecular weight:417.5

    Ref: TM-T5384

  • BMS-813160
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    BMS-813160

    CAS:
    <p>BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.</p>
    Formula:C25H40N8O2
    Purity:99.66% - 99.79%
    Color and Shape:Solid
    Molecular weight:484.64

    Ref: TM-T4584

  • DAPTA
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    DAPTA

    CAS:
    <p>DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.</p>
    Formula:C35H56N10O15
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:856.88

    Ref: TM-T7624

  • Vercirnon sodium
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    Vercirnon sodium

    CAS:
    <p>Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.</p>
    Formula:C22H21ClN2NaO4S
    Color and Shape:Solid
    Molecular weight:467.92

    Ref: TM-T41016

  • AZD2098
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    AZD2098

    CAS:
    <p>AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.</p>
    Formula:C11H9Cl2N3O3S
    Purity:99.80% - >99.99%
    Color and Shape:Solid
    Molecular weight:334.18

    Ref: TM-T4300

  • Cenicriviroc
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    Cenicriviroc

    CAS:
    <p>Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.</p>
    Formula:C41H52N4O4S
    Purity:97.87%
    Color and Shape:Solid
    Molecular weight:696.94

    Ref: TM-TQ0297

  • INCB 3284
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    INCB 3284

    CAS:
    <p>INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.</p>
    Formula:C26H31F3N4O4
    Purity:97.81% - 99.42%
    Color and Shape:Solid
    Molecular weight:520.54

    Ref: TM-T11648

  • CymitQuimica logo
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    Carlumab

    CAS:
    <p>Carlumab is a high-affinity human monoclonal antibody that targets CCL2, suppressing the recruitment of monocytes/macrophages in the tumour microenvironment.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T76740

  • Tivumecirnon
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    Tivumecirnon

    CAS:
    <p>Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumour</p>
    Formula:C24H27Cl2F3N6O
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:543.41

    Ref: TM-T69834

  • BI-6901
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    BI-6901

    CAS:
    <p>BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.</p>
    Formula:C23H27N5O3S
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:453.56

    Ref: TM-T36478

  • CCR4 antagonist 3-1
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    CCR4 antagonist 3-1

    CAS:
    <p>CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with IC50 values of 1.7 μM and 6.4 μM, respectively.</p>
    Formula:C14H12N2S
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:240.32

    Ref: TM-T60336

  • CCR1 antagonist 9
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    CCR1 antagonist 9

    CAS:
    <p>CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.</p>
    Formula:C20H16FN5O3S
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:425.44

    Ref: TM-T10710

  • CCR8 antagonist 2
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    CCR8 antagonist 2

    CAS:
    <p>CCR8 antagonist 2 blocks CCR8 activity, mainly on Treg and Th2 cells, for treating related diseases. See WO2022000443A1, compound 220.</p>
    Formula:C23H30ClN3O3S
    Color and Shape:Solid
    Molecular weight:464.02

    Ref: TM-T62944

  • YM022
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    YM022

    CAS:
    <p>YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist.</p>
    Formula:C32H28N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:516.59

    Ref: TM-T17274

  • CCR2 antagonist 3
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    CCR2 antagonist 3

    CAS:
    <p>CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.</p>
    Formula:C17H25FN2O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:308.39

    Ref: TM-T10712

  • GW 766994
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    GW 766994

    CAS:
    <p>GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.</p>
    Formula:C21H24Cl2N4O3
    Purity:98.77%
    Color and Shape:Solid
    Molecular weight:451.35

    Ref: TM-T11521

  • CCR1 antagonist 7
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    CCR1 antagonist 7

    CAS:
    <p>CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].</p>
    Formula:C21H24ClN5O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.96

    Ref: TM-T10709

  • RPT193
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    RPT193

    CAS:
    <p>RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.</p>
    Formula:C27H34Cl3N5O2
    Color and Shape:Solid
    Molecular weight:566.95

    Ref: TM-T64013

  • ALK4290
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    ALK4290

    CAS:
    <p>ALK4290 (AKST4290), a potent oral CCR3 inhibitor with a Ki of 3.2 nM, may treat macular degeneration and Parkinsonism.</p>
    Formula:C27H34ClN5O3
    Color and Shape:Solid
    Molecular weight:512.04

    Ref: TM-T36620

  • CCX354
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    CCX354

    CAS:
    <p>CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.</p>
    Formula:C22H22ClN7O2
    Purity:99.82% - 99.82%
    Color and Shape:Solid
    Molecular weight:451.91

    Ref: TM-T15253