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CCR

CCR

C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.

Found 136 products of "CCR"

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  • Plozalizumab
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    Plozalizumab

    CAS:
    <p>Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of</p>
    Purity:96.4%
    Color and Shape:Liquid
    Molecular weight:146.02 kDa

    Ref: TM-T77118

  • SQA1
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    SQA1

    CAS:
    <p>SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.</p>
    Formula:C22H26N4O5
    Color and Shape:Solid
    Molecular weight:426.47

    Ref: TM-T88146

  • 2-Methoxyhydroquinone
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    2-Methoxyhydroquinone

    CAS:
    <p>2-Methoxyhydroquinone inhibits MAO-A and MAO-B and reduces TNF-α-induced CCL2 production, a precursor for synthesising the Hsp90 inhibitor Geldanamycin.</p>
    Formula:C7H8O3
    Purity:98.25%
    Color and Shape:Solid
    Molecular weight:140.14

    Ref: TM-T203475

  • WAY-639418
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    WAY-639418

    CAS:
    <p>WAY-639418 has potential anti-inflammatory and anti-HIV activity and can be used to study CCR5-mediated inflammatory and immunomodulatory diseases.</p>
    Formula:C17H16ClN5
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:325.8

    Ref: TM-T9942

  • Vercirnon
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    Vercirnon

    CAS:
    <p>Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.</p>
    Formula:C22H21ClN2O4S
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:444.93

    Ref: TM-T17225

  • DAPTA
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    DAPTA

    CAS:
    <p>DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.</p>
    Formula:C35H56N10O15
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:856.88

    Ref: TM-T7624

  • BMS-813160
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    BMS-813160

    CAS:
    <p>BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.</p>
    Formula:C25H40N8O2
    Purity:99.66% - 99.79%
    Color and Shape:Solid
    Molecular weight:484.64

    Ref: TM-T4584

  • AZD-4818
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    AZD-4818

    CAS:
    <p>AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.</p>
    Formula:C27H32Cl2N2O7
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:567.46

    Ref: TM-T30258

  • Vicriviroc maleate
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    Vicriviroc maleate

    CAS:
    <p>Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.</p>
    Formula:C32H42F3N5O6
    Purity:98.16% - 98.37%
    Color and Shape:Solid
    Molecular weight:649.7

    Ref: TM-T3435

  • Vercirnon sodium
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    Vercirnon sodium

    CAS:
    <p>Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.</p>
    Formula:C22H21ClN2NaO4S
    Color and Shape:Solid
    Molecular weight:467.92

    Ref: TM-T41016

  • Cenicriviroc
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    Cenicriviroc

    CAS:
    <p>Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.</p>
    Formula:C41H52N4O4S
    Purity:97.87%
    Color and Shape:Solid
    Molecular weight:696.94

    Ref: TM-TQ0297

  • Bindarit
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    Bindarit

    CAS:
    <p>Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.</p>
    Formula:C19H20N2O3
    Purity:98.35% - 98.55%
    Color and Shape:Solid
    Molecular weight:324.37

    Ref: TM-T6413

  • RE-640
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    RE-640

    CAS:
    <p>NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.</p>
    Formula:C20H16Cl2N4
    Purity:99.60% - 99.87%
    Color and Shape:Solid
    Molecular weight:383.27

    Ref: TM-T3188

  • 7,4'-Dihydroxyflavone
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    7,4'-Dihydroxyflavone

    CAS:
    <p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>
    Formula:C15H10O4
    Purity:99.39% - 99.6%
    Color and Shape:Solid
    Molecular weight:254.24

    Ref: TM-TN1273

  • RS102895
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    RS102895

    CAS:
    <p>RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.</p>
    Formula:C21H21F3N2O2
    Purity:97.64% - 99.80%
    Color and Shape:Solid
    Molecular weight:390.4

    Ref: TM-TQ0283

  • CCR2 antagonist 4 hydrochloride
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    CCR2 antagonist 4 hydrochloride

    CAS:
    <p>CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).</p>
    Formula:C21H22Cl2F3N3O2
    Color and Shape:Solid
    Molecular weight:476.32

    Ref: TM-T19230

  • PF-4136309
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    PF-4136309

    CAS:
    <p>PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.</p>
    Formula:C29H31F3N6O3
    Purity:98.85% - 99.47%
    Color and Shape:Solid
    Molecular weight:568.59

    Ref: TM-T3430

  • RS 504393
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    RS 504393

    CAS:
    <p>RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and &gt; 100 μM for human recombinant CCR2 and CCR1).</p>
    Formula:C25H27N3O3
    Purity:98.64% - 99.62%
    Color and Shape:Solid
    Molecular weight:417.5

    Ref: TM-T5384

  • ZK 756326
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    ZK 756326

    CAS:
    <p>ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.</p>
    Formula:C21H28N2O3
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:356.46

    Ref: TM-T3360

  • SB297006
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    SB297006

    CAS:
    <p>SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.</p>
    Formula:C18H18N2O5
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:342.35

    Ref: TM-T4674