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PGE Synthase

PGE Synthase

Prostaglandin E synthase (PGE synthase) is an enzyme involved in the biosynthesis of prostaglandin E2 (PGE2), a lipid mediator that plays a key role in inflammation, pain, and fever. PGE2 is involved in various physiological processes, including immune responses, vascular function, and gastrointestinal health. Dysregulation of PGE2 production is associated with inflammatory diseases, cancer, and cardiovascular disorders. At CymitQuimica, we offer a selection of PGE synthase inhibitors and modulators to support your research in inflammation, pain management, and disease pathology.

Found 33 products for "PGE Synthase".

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  • Sinensetin
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    Sinensetin

    CAS:
    Sinensetin, a citrus flavone, has antiangiogenic, anti-inflammatory properties, and promotes fat formation and breakdown.
    Formula:C20H20O7
    Purity:97.74% - 99.8%
    Color and Shape:Solid
    Molecular weight:372.3686

    Ref: TM-T4S0227

  • hPGDS-IN-1
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    hPGDS-IN-1

    CAS:
    hPGDS-IN-1 is a hPGDS inhibitor.
    Formula:C22H20N6O3
    Purity:99.77% - >99.99%
    Color and Shape:White Solid
    Molecular weight:416.4326

    Ref: TM-T2681

  • (S)-Flurbiprofen
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    (S)-Flurbiprofen

    CAS:
    Esflurbiprofen is an inhibitor of COX-1 and COX-2.
    Formula:C15H13FO2
    Purity:99.99%
    Color and Shape:White Solid
    Molecular weight:244.2609

    Ref: TM-T5843L

  • Dehydroevodiamine
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    Dehydroevodiamine

    CAS:
    Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant
    Formula:C19H15N3O
    Purity:99.54%
    Color and Shape:Yellow Solid
    Molecular weight:301.3419

    Ref: TM-T2S2335

  • CAFESTOL
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    CAFESTOL

    CAS:
    Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.
    Formula:C20H28O3
    Purity:97.06% - 99.08%
    Color and Shape:Yellow Solid
    Molecular weight:316.4345

    Ref: TM-T5727

  • mPGES-1 Inhibitor-1
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    mPGES-1 Inhibitor-1

    CAS:
    mPGES-1 Inhibitor-1 is an mPGES-1 inhibitor with anti-inflammatory and analgesic activity, which can be used to study acute liver injury.
    Formula:C16H19ClN4O2
    Purity:96.84% - 98.75%
    Color and Shape:Solid
    Molecular weight:334.8

    Ref: TM-T28089

  • Clopirac
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    Clopirac

    CAS:
    Clopirac is a prostaglandin synthase inhibitor with anti-inflammatory activity.
    Formula:C14H14ClNO2
    Color and Shape:Solid
    Molecular weight:263.719

    Ref: TM-T60431

  • F092
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    F092

    CAS:
    F092 is a potent inhibitor of hematopoietic prostaglandin D synthetase (H-PGDS), which can be used to study allergic inflammation and vascular-related diseases.
    Formula:C20H17N5O2
    Purity:99.93%
    Color and Shape:Yellow Solid
    Molecular weight:359.38

    Ref: TM-T69730

  • Friluglanstat
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    Friluglanstat

    CAS:
    Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].
    Formula:C25H20ClF3N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:516.9

    Ref: TM-T79846

  • mPGES1-IN-3
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    mPGES1-IN-3

    CAS:
    mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .
    Formula:C24H16ClF5N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:538.85

    Ref: TM-T12100

  • mPGES1-IN-9
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    mPGES1-IN-9

    CAS:
    mPGES1-IN-9 (compound 1_8) is an mPGES1 inhibitor with an IC50 of 0.5 μM and is utilized in anti-inflammatory research.
    Formula:C25H18N4OS
    Color and Shape:Solid
    Molecular weight:422.502

    Ref: TM-T204717

  • PF-4693627
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    PF-4693627

    CAS:
    PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM).
    Formula:C26H29Cl2N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:502.43

    Ref: TM-T16504

  • α-Gracinoic acid
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    α-Gracinoic acid

    CAS:
    α-Gracinoic acid acts as an inhibitor of mPGES-1, exhibiting anti-inflammatory properties.
    Formula:C29H42O4
    Color and Shape:Solid
    Molecular weight:454.64

    Ref: TM-T200464