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Nrf2

Nrf2

Nrf2 is a transcription factor that regulates the expression of antioxidant proteins and detoxification enzymes, playing a pivotal role in cellular defense against oxidative stress and inflammation. Activation of Nrf2 signaling provides protection against various diseases, including cancer, neurodegeneration, and cardiovascular disorders. Nrf2 modulators are being explored for their potential therapeutic applications in reducing oxidative damage and inflammation. At CymitQuimica, we provide a range of high-quality Nrf2 pathway modulators to support your research in oxidative stress, inflammation, and disease prevention.

Found 79 products of "Nrf2"

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  • ML162
    Targetmol
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    ML162

    CAS:
    <p>ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C23H22Cl2N2O3S
    Purity:98.42% - 99.55%
    Color and Shape:Solid
    Molecular weight:477.4

    Ref: TM-T8970

  • Diroximel fumarate
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    Diroximel fumarate

    CAS:
    <p>Diroximel fumarate (Diroximel Fumarete), a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.</p>
    Formula:C11H13NO6
    Purity:99.8% - 99.88%
    Color and Shape:Solid
    Molecular weight:255.22

    Ref: TM-T4271

  • AT 14 acetate
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    AT 14 acetate

    TAT 14 acetate, a 14-mer peptide, activates Nrf2, has anti-inflammatory effects, and targets Keap1 without altering Nrf2 mRNA.
    Formula:C139H234N48O41
    Purity:96.9%
    Color and Shape:Solid
    Molecular weight:3233.64

    Ref: TM-TP2109L

  • 4-Octyl itaconate
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    4-Octyl itaconate

    CAS:
    <p>4-Octyl Itaconate is a cell-permeable derivative of Itaconate, an anti-inflammatory metabolite.</p>
    Formula:C13H22O4
    Purity:99.3% - 99.94%
    Color and Shape:Solid
    Molecular weight:242.31

    Ref: TM-T4580

  • Kinsenoside
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    Kinsenoside

    CAS:
    <p>Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.</p>
    Formula:C10H16O8
    Purity:99.2% - >99.99%
    Color and Shape:Solid
    Molecular weight:264.23

    Ref: TM-T3849

  • Artemisitene
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    Artemisitene

    CAS:
    <p>Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.</p>
    Formula:C15H20O5
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:280.32

    Ref: TM-T21065

  • CBR-470-1
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    CBR-470-1

    CAS:
    <p>CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.</p>
    Formula:C14H20ClNO4S2
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:365.9

    Ref: TM-T40063

  • L-Cystine dihydrochloride
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    L-Cystine dihydrochloride

    CAS:
    <p>L-Cystine dihydrochloride, a sulfur-based glutathione precursor, maintains GSH balance, used in cell culture.</p>
    Formula:C6H14Cl2N2O4S2
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:313.22

    Ref: TM-T60789

  • MIND4-17
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    MIND4-17

    CAS:
    <p>MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.</p>
    Formula:C20H15N5O3S
    Color and Shape:Solid
    Molecular weight:405.43

    Ref: TM-T69401

  • Nrf2-Activator-12G
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    Nrf2-Activator-12G

    CAS:
    <p>Nrf2-Activator-12G is a potent Nrf-2 activator.</p>
    Formula:C15H13ClO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.78

    Ref: TM-T24546

  • MSU38225
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    MSU38225

    CAS:
    <p>MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.</p>
    Formula:C21H19N3
    Color and Shape:Solid
    Molecular weight:313.4

    Ref: TM-T79146

  • (+)-DHMEQ
    Targetmol
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    (+)-DHMEQ

    CAS:
    <p>(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.</p>
    Formula:C13H11NO5
    Color and Shape:Solid
    Molecular weight:261.23

    Ref: TM-T13462

  • Dihydrolipoic acid
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    Dihydrolipoic acid

    CAS:
    <p>Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various reactive oxygen species at 0.01-0.5 mM.</p>
    Formula:C8H16O2S2
    Purity:97.51%
    Color and Shape:Yellow To Orange Liquid
    Molecular weight:208.34

    Ref: TM-T21233

  • Keap1-Nrf2-IN-12
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    Keap1-Nrf2-IN-12

    CAS:
    <p>eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.</p>
    Formula:C26H28N2O10S2
    Color and Shape:Solid
    Molecular weight:592.64

    Ref: TM-T64190

  • Keap1-Nrf2-IN-13
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    Keap1-Nrf2-IN-13

    CAS:
    <p>Keap1-Nrf2-IN-13 is a PPI inhibitor (IC50: 0.15 μM) that binds Keap1 strongly, useful for oxidative stress and inflammation research.</p>
    Formula:C28H32N2O10S2
    Color and Shape:Solid
    Molecular weight:620.69

    Ref: TM-T72706

  • Nrf2 activator-5
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    Nrf2 activator-5

    CAS:
    <p>Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.</p>
    Formula:C25H30Cl2O6
    Color and Shape:Solid
    Molecular weight:497.41

    Ref: TM-T63364

  • Keap1-Nrf2-IN-14
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    Keap1-Nrf2-IN-14

    CAS:
    <p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>
    Formula:C30H29NO8S
    Color and Shape:Solid
    Molecular weight:563.62

    Ref: TM-T63987

  • NXPZ-2
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    NXPZ-2

    CAS:
    <p>NXPZ-2, an oral Keap1-Nrf2 PPI inhibitor (Ki: 95 nM, EC50: 120-170 nM), may improve cognition and neuron health in AD.</p>
    Formula:C27H27N5O7S2
    Color and Shape:Solid
    Molecular weight:597.66

    Ref: TM-T64214

  • SPC-180002
    Targetmol
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    SPC-180002

    CAS:
    <p>SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.</p>
    Formula:C18H23NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:317.38

    Ref: TM-T79601

  • Stigmane B
    Targetmol
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    Stigmane B

    <p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>
    Formula:C21H30O4
    Color and Shape:Solid
    Molecular weight:346.46

    Ref: TM-T73201