Nrf2
Nrf2 is a transcription factor that regulates the expression of antioxidant proteins and detoxification enzymes, playing a pivotal role in cellular defense against oxidative stress and inflammation. Activation of Nrf2 signaling provides protection against various diseases, including cancer, neurodegeneration, and cardiovascular disorders. Nrf2 modulators are being explored for their potential therapeutic applications in reducing oxidative damage and inflammation. At CymitQuimica, we provide a range of high-quality Nrf2 pathway modulators to support your research in oxidative stress, inflammation, and disease prevention.
Found 82 products of "Nrf2"
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Monascin
CAS:Monascin: azaphilonoid in red-mold rice; anti-tumor and anti-inflammatory.Formula:C21H26O5Purity:98%Color and Shape:SolidMolecular weight:358.43Keap1-IN-1
Keap1-IN-1 (Compound 27) is an inhibitor of Keap1, functioning by covalently modifying the Cys151 residue on the BTB domain of KEAP1, thereby disrupting the interaction between Keap and Nrf. It enhances the mRNA expression of the antioxidant response element (ARE) dependent gene NQO1, with an EC50 of 160 nM, and exhibits cytotoxicity in U2OS cells, with an EC50 of 527 nM.Formula:C17H21Cl2N2O5PS3Color and Shape:SolidMolecular weight:531.434His-Pro
CAS:His-Pro is a dipeptide consisting of histidyl and proline.Formula:C11H16N4O3Purity:98%Color and Shape:SolidMolecular weight:252.2717-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
CAS:Aspirin-enhanced COX-2 metabolite of DHA, activates Nrf2 and PPARγ, inhibits inflammation, with EC50 ~200 nM, effective at 5-25 μM.Formula:C22H30O3Color and Shape:SolidMolecular weight:342.479Pterisolic acid B
Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.Formula:C20H26O4Color and Shape:SolidMolecular weight:330.424TAT 14
CAS:TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Formula:C137H230N48O39Purity:98%Color and Shape:SolidMolecular weight:3173.59TPNA10168
CAS:Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H9ClO2S2Color and Shape:SolidMolecular weight:248.75S217879
CAS:S217879 is a potent and selective activator of NRF2 that disrupts the KEAP1-NRF2 interaction, resulting in significant activation of the NRF2 pathway.Formula:C30H32N4O7SColor and Shape:SolidMolecular weight:592.67Keap1-Nrf2-IN-9
CAS:Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.Formula:C31H30N2O11S2Color and Shape:SolidMolecular weight:670.71Ac-LDEETGEFL-NH2
CAS:Ac-LDEETGEFL-NH2 is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factorFormula:C48H72N10O19Color and Shape:SolidMolecular weight:1093.144-P-PDOT
CAS:4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.Formula:C19H21NOPurity:99.91%Color and Shape:SolidMolecular weight:279.38CBR-470-2
CAS:CBR-470-2 activates NRF2 signaling, aiding in glycolysis research.Formula:C12H13Cl2NO6S2Color and Shape:SolidMolecular weight:402.26Dimethyl fumarate-d6
CAS:Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. can induces upregulation of antioxidant gene expression.Formula:C6H8O4Purity:98%Color and Shape:SolidMolecular weight:150.16KI696 isomer
CAS:KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Formula:C28H30N4O6SPurity:99.8%Color and Shape:SolidMolecular weight:550.63Ref: TM-T11758
1mg87.00€5mg264.00€10mg442.00€25mg892.00€50mg1,198.00€100mg1,575.00€1mL*10mM (DMSO)289.00€Anti-NFE2L2 Antibody (6K859)
Anti-NFE2L2 Antibody (6K859) is an antibody targeting NFE2L2. Anti-NFE2L2 Antibody (6K859) can be used in ELISA, IF.Color and Shape:Odour LiquidAnti-Phospho-NFE2L2 (Ser40) Antibody (6V851)
Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) is an antibody targeting Phospho-NFE2L2 (Ser40). Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidAnti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Purity:>95%Color and Shape:Odour LiquidI-152
CAS:Bepranemab (UCB 0107) is a humanized IgG monoclonal antibody against tau for the study of Alzheimer's disease (AD) and tau proteinopathies.Formula:C9H16N2O3S2Purity:98.36%Color and Shape:SolidMolecular weight:264.37ML334
CAS:ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.
Formula:C26H26N2O5Purity:98.06% - 98.06%Color and Shape:SolidMolecular weight:446.49ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurity:98.42% - 99.55%Color and Shape:SolidMolecular weight:477.4Ref: TM-T8970
1mg43.00€5mg85.00€10mg110.00€25mg215.00€50mg334.00€100mg467.00€200mg672.00€1mL*10mM (DMSO)92.00€
