Nrf2
Nrf2 is a transcription factor that regulates the expression of antioxidant proteins and detoxification enzymes, playing a pivotal role in cellular defense against oxidative stress and inflammation. Activation of Nrf2 signaling provides protection against various diseases, including cancer, neurodegeneration, and cardiovascular disorders. Nrf2 modulators are being explored for their potential therapeutic applications in reducing oxidative damage and inflammation. At CymitQuimica, we provide a range of high-quality Nrf2 pathway modulators to support your research in oxidative stress, inflammation, and disease prevention.
Found 84 products for "Nrf2".
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4-P-PDOT
CAS:4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.Formula:C19H21NOPurity:99.91%Color and Shape:White SolidMolecular weight:279.38Nrf2 activator-1
CAS:Nrf2 activator-1 activates Nrf2; used for COPD, asthma, ALI, ARDS, pulmonary fibrosis research.Formula:C30H34N4O6SPurity:97.8%Color and Shape:SolidMolecular weight:578.679Fraxinellone analog 1
Fraxinellone analog 1 (compound 2) is an effective and rapid activator of the Nrf2-mediated antioxidative defense system, providing protection against glutamate-mediated excitotoxicity. It induces the expression of antioxidative genes Gpx4, Sod1, and Nqo1. Additionally, Fraxinellone analog 1 exerts neuroprotective effects and modulates oxidative stress and inflammation, making it suitable for research on neurodegenerative diseases.Color and Shape:Odour SolidAnticonvulsant agent 10
Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.Color and Shape:Odour SolidKeap1/Nrf2/ARE activator 1
Keap1/Nrf2/ARE activator 1 (compound HT-3) functions as an activator of the Keap1/Nrf2/ARE pathway. This compound has antioxidant properties and offers neuroprotective effects.Formula:C19H20O6Color and Shape:SolidMolecular weight:344.12599Keap1-Nrf2-IN-23
CAS:Keap1-Nrf2-IN-23 (compound 56) acts as an inhibitor of the Keap1–Nrf2 PPI (IC50=16.0 nM). It exhibits a Kd value of 3.07 nM when binding to Keap1 and demonstrates oral activity.Formula:C30H31ClN4O5Color and Shape:SolidMolecular weight:563.04Nrf2 activator 18
Nrf2 activator 18 (Compound 11a) is an orally active activator of the Keap1/Nrf2/HO-1 signaling pathway, promoting Nrf2 nuclear translocation and enhancing antioxidant effects. It inhibits IL-6 release with an IC50 of 4.816 μM. In a mouse model of PM2.5-induced lung injury, Nrf2 activator 18 demonstrates anti-inflammatory activity.Formula:C23H24FN3OColor and Shape:SolidMolecular weight:377.45TAT 14
CAS:TAT 14: a 14-mer peptide Nrf2 activator, anti-inflammatory, boosts Nrf2 protein, targets Keap1, no effect on mRNA.Formula:C137H230N48O39Purity:98%Color and Shape:SolidMolecular weight:3173.59Keap1-Nrf2-IN-27
Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.Color and Shape:Odour SolidS217879
CAS:S217879 is a potent and selective activator of NRF2 that disrupts the KEAP1-NRF2 interaction, resulting in significant activation of the NRF2 pathway.Formula:C30H32N4O7SColor and Shape:SolidMolecular weight:592.67KI696 isomer
CAS:KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases.Formula:C28H30N4O6SPurity:99.98%Color and Shape:White SolidMolecular weight:550.626Dimethyl fumarate-D6
CAS:Dimethyl fumarate-D6 is a deuterium labeled Dimethyl fumarate (T0492). can induces upregulation of antioxidant gene expression.Formula:C6H8O4Purity:98%Color and Shape:SolidMolecular weight:150.1623Anti-NFE2L2 Antibody (6K859)
Anti-NFE2L2 Antibody (6K859) is an antibody targeting NFE2L2. Anti-NFE2L2 Antibody (6K859) can be used in ELISA, IF.Color and Shape:Odour LiquidAnti-Phospho-NFE2L2 (Ser40) Antibody (6V851)
Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) is an antibody targeting Phospho-NFE2L2 (Ser40). Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) can be used in ELISA, WB, IHC, IF.Color and Shape:Odour LiquidAnti-NFE2L2 Antibody (9K94)
Anti-NFE2L2 Antibody (9K94) is a Mouse antibody targeting NFE2L2. Anti-NFE2L2 Antibody (9K94) can be used in ELISA, WB, IHC, IF, FCM.Purity:>95%Color and Shape:Odour LiquidI-152
CAS:Bepranemab (UCB 0107) is a humanized IgG monoclonal antibody against tau for the study of Alzheimer's disease (AD) and tau proteinopathies.Formula:C9H16N2O3S2Purity:98.36%Color and Shape:SolidMolecular weight:264.37CBR-470-2
CAS:CBR-470-2 activates NRF2 signaling, aiding in glycolysis research.Formula:C12H13Cl2NO6S2Color and Shape:SolidMolecular weight:402.271Dibenzoylmethane (Standard)
CAS:Dibenzoylmethane (Standard) is the standard substance of Dibenzoylmethane, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments.Formula:C15H12O2Molecular weight:224.2546ML334
CAS:ML334 (LH601A) is an NRF2 activator that inhibits cardiac fibroblast activation and proliferation ameliorating myocardial infarction-induced cardiac fibrosis.Formula:C26H26N2O5Purity:98.06% - 98.06%Color and Shape:SolidMolecular weight:446.495Diroximel fumarate
CAS:Diroximel fumarate (Diroximel Fumarete), a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.Formula:C11H13NO6Purity:99.8% - 99.88%Color and Shape:SolidMolecular weight:255.224
